Searched for: author:"Giagka, V."
(1 - 14 of 14)
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Kawasaki, S. (author), Giagka, V. (author), de Haas, M (author), Louwerse, M. (author), Henneken, V (author), van Heesch, C. (author), Dekker, R. (author)
Vagus nerve stimulators currently on the market can treat epilepsy and depression. Recent clinical trials show the potential for vagus nerve stimulation (VNS) to treat epilepsy, autoimmune disease, and traumatic brain injury. As we explore the benefits of VNS, it is expected that more possibilities for a new treatment will emerge in the future....
conference paper 2019
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Bakhshaee Babaroud, N. (author), Kluba, M.M. (author), Dekker, R. (author), Serdijn, W.A. (author), Giagka, V. (author)
Active implantable medical devices have been developed for diagnosis, monitoring and treatment of large variety of neural disorders. Since the mechanical properties of these devices need to be matched to the tissue, soft materials, such as polymers are often preferred as a substrate [1]. Parylene is a good candidate, as it is highly...
abstract 2019
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Malissovas, Anastasios (author), Serdijn, W.A. (author), Giagka, V. (author)
As the era of Bioelectronic medicines (BEms) evolves, new technological challenges are generated, including miniaturized devices that are encapsulated with flexible materials and energized by wireless power transmission (WPT) techniques. Among them, magnetostatic, also known as inductive, and ultrasound (US) are the most viable candidates for...
abstract 2019
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Wardhana, Gandhika K (author), Serdijn, W.A. (author), Vollebregt, S. (author), Giagka, V. (author), Vollebregt, Sten (author)
Neural interface in the form of microelectrodes are used to monitor and treat spinal cord injury and other neurological disorders by the means of recording and stimulation. Despite of the apparent result of these electrical interventions, understanding of the mechanism behind neural stimulation is still inadequate. The use of optical monitoring...
abstract 2019
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Martins da Ponte, R. (author), Huang, C. (author), Giagka, V. (author), Serdijn, W.A. (author)
Optogenetics is a neuromodulation method that holds great potential for the realization of advanced neuroprostheses due to its precise spatial-temporal control of neuronal activity [1]. The development of novel optogenetic implants (optrodes) may open new doors to investigate complex brain circuitry and chronical brain disorders, such as...
abstract 2019
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Martins da Ponte, R. (author), Giagka, V. (author), Serdijn, W.A. (author)
Incubators in cell cultures are used to grow and maintain cells under optimal temperature alongside other key variables, such as pH, humidity, atmospheric conditions etc. As enzymatic activity and protein synthesis proceed optimally at 37.5 oC, a temperature rise can cause protein denaturation, whereas a drop in temperature can slow down...
abstract 2019
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Nanbakhsh, K. (author), Serdijn, W.A. (author), Giagka, V. (author)
The main goal of bioelectronic medicine is to, one day, replace conventional chemical drugs with miniaturized implants. This way, tiny electrical pulses will be locally delivered to a small group of neurons in order to influence and modify biological functions. Developing such implants, however, has brought many new challenges both in the...
abstract 2019
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Pak, A. (author), Serdijn, W.A. (author), Giagka, V. (author)
Electronic components in the form of application-specific integrated circuits (ASICs) establishing the communication between the body and the implant, such as stimulation and recording, have, nowadays, become essential elements for current and future generations of implantable devices, as medicine is looking into substituting its traditional...
abstract 2019
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Martins da Ponte, R. (author), Giagka, V. (author), Serdijn, W.A. (author)
This paper reports on the design and fabrication of a time-mode signal-processing in situ temperature sensor customized for an organ-on-a-chip (OOC) application. The circuit was fabricated using an in-house integrated circuit (IC) technology that requires only seven lithographic steps and is compatible with MEMS fabrication process. The...
conference paper 2018
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Tacchetti, Lucia (author), Serdijn, W.A. (author), Giagka, V. (author)
This paper presents the design of a neurostimulator performing biphasic ultra-high-frequency electrical stimulation while being driven from ultrasound energy. Unlike conventional constant current or constant voltage stimulators or state-of-the-art ultra-high-frequency stimulators, the system does not convert the input AC signal into regulated...
conference paper 2018
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Olafsdottir, Gudrun Erla (author), Serdijn, W.A. (author), Giagka, V. (author)
This paper presents the design and fabrication of an implantable control unit intended for epidural spinal cord stimulation (ESCS) in rats. The device offers full programmability over stimulation parameters and delivers a constant current to an electrode array to be located within the spinal canal. It implements an adaptive voltage compliance...
conference paper 2018
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Giagka, V. (author), Serdijn, W.A. (author)
Patients suffering from conditions such as paralysis, diabetes or rheumatoid arthritis could in the future be treated in a personalised manner using bioelectronic medicines (BEms) (Nat Rev Drug Discov 13:399–400, 2013, Proc Natl Acad Sci USA 113:8284–9, 2016, J Intern Med 282:37–45, 2017). To deliver this personalised therapy based on...
journal article 2018
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Giagka, V. (author), Demosthenous, A. (author), Donaldson, N. (author)
Epidural spinal cord electrical stimulation (ESCS) has been used as a means to facilitate locomotor recovery in spinal cord injured humans. Electrode arrays, instead of conventional pairs of electrodes, are necessary to investigate the effect of ESCS at different sites. These usually require a large number of implanted wires, which could lead to...
journal article 2015
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Giagka, V. (author), Demosthenous, Andreas (author), Donaldson, N (author)
Epidural spinal cord electrical stimulation (ESCS) has been used as a means to facilitate locomotor recovery in spinal cord injured humans. Electrode arrays, instead of conventional pairs of electrodes, are necessary to investigate the effect of ESCS at different sites. These usually require a large number of implantedwires,which could lead to...
journal article 2015
Searched for: author:"Giagka, V."
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