Improved estimation of the temporal decay function of in vivo metabolite signals

MRI-scanners enable non-invasive, in vivo quantitation of metabolites in, e.g., the brain of a patient. Among other things, this requires adequate estimation of the unknown temporal decay function of the complex-valued signal emanating from the metabolites. We propose a method to render a current decay estimator more simple, accurate, and robust...

Dynamic MR-Imaging with Radial Scanning, a Post-Acquisition Keyhole Approach

A new method for 2D/3D dynamic MR-Imaging with radial scanning is proposed. It exploits the inherent strong oversampling in the centre of k-space, which holds crucial temporal information of the contrast evolution. It is based on (1) a rearrangement of (novel 3D) isotropic distributions of trajectories during the scan according to the desired...

Error-Bars in Semi-Parametric Estimation

In in vivo metabolite-quantitation with a magnetic resonance spectroscopy (MRS) scanner, the model function of the attendant MRS signal is often only partly known. This unfavourable condition requires semi-parametric estimation. In the present study the unknown part is the form of the decay function of the MRS signal. The lack of knowledge is...