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Hards, Kiel (author), McMillan, D.G.G. (author), Schurig-Briccio, Lici A. (author), Gennis, Robert B. (author), Lill, Holger (author), Bald, Dirk (author), Cook, Gregory M. (author)
Bedaquiline (BDQ), an inhibitor of the mycobacterial F<sub>1</sub>F<sub>o</sub>-ATP synthase, has revolutionized the antitubercular drug discovery program by defining energy metabolism as a potent new target space. Several studies have recently suggested that BDQ ultimately causes mycobacterial cell death through a phenomenon known as...
journal article 2018