"uuid","repository link","title","author","contributor","publication year","abstract","subject topic","language","publication type","publisher","isbn","issn","patent","patent status","bibliographic note","access restriction","embargo date","faculty","department","research group","programme","project","coordinates" "uuid:4bdfa218-5093-42b1-b26a-bb8c0ffe661e","http://resolver.tudelft.nl/uuid:4bdfa218-5093-42b1-b26a-bb8c0ffe661e","Limited added value of magnetic resonance imaging after dynamic transvaginal ultrasound for preoperative staging of endometriosis in daily practice: A prospective cohort study","Berger, Judith P. (Bronovo Hospital; Leiden University Medical Center); Rhemrev, Johann (Bronovo Hospital); Smeets, Maddy (Bronovo Hospital); Henneman, Onno (Bronovo Hospital); English, James (Bronovo Hospital); Jansen, F.W. (TU Delft Medical Instruments & Bio-Inspired Technology; Leiden University Medical Center)","","2019","OBJECTIVES: To assess the added value of magnetic resonance imaging (MRI) after dynamic transvaginal ultrasound (TVUS) in the diagnostic pathway for preoperative staging of pelvic endometriosis. METHODS: A prospective observational study was conducted between April 22, 2014, and May 1, 2015. During that period, 363 patients with a clinical suspicion of endometriosis were included. All patients underwent a history, clinical examination, and dynamic TVUS examination. Most of the patients (nā€‰=ā€‰274) underwent conservative treatment according to the European Society of Human Reproduction and Embryology guidelines. Eighty-nine patients were selected for surgery, of whom 72 patients underwent the complete diagnostic pathway: ie, history, clinical examination, dynamic TVUS, and MRI. All data were analyzed by the nonparametric McNemar test for comparing each step in the diagnostic algorithm. RESULTS: The sensitivity and specificity for the history, pelvic examination, and dynamic TVUS were 93.7% and 55.6% (Pā€‰<ā€‰.001), respectively; when MRI findings were included, the sensitivity and specificity were 85.9% and 62.5%. Adding MRI routinely to the diagnostic procedure of endometriosis did not significantly improve the sensitivity or specificity. CONCLUSIONS: There is no significant added value of routine MRI after dynamic TVUS for the preoperative staging of endometriosis.","diagnosis; endometriosis; gynecology; magnetic resonance imaging; transvaginal ultrasound","en","journal article","","","","","","","","","","","Medical Instruments & Bio-Inspired Technology","","",""