Searched for: author%3A%22Kenjeres%2C+S.%22
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Van den Eynde, Jef (author), Westenberg, Jos J.M. (author), Hazekamp, Mark G. (author), Lamb, Hildo J. (author), Jongbloed, Monique R.M. (author), Wentzel, Jolanda J. (author), Kenjeres, S. (author), Dekkers, Ilona A. (author), Rijnberg, F.M. (author)
BACKGROUND: Kidney disease is the most important predictor of death in patients with a Fontan circulation, yet its clinical and hemodynamic correlates have not been well established. METHODS AND RESULTS: A total of 53 ambulatory patients with a Fontan circulation (median age, 16.2 years, 52.8% male patients) underwent advanced cardiovascular...
journal article 2024
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Geronzi, Leonardo (author), Fanni, Benigno Marco (author), De Jong, Bart (author), Roest, G.T.H. (author), Kenjeres, S. (author), Celi, Simona (author), Biancolini, Marco Evangelos (author)
The treatment for asthma and chronic obstructive pulmonary disease relies on forced inhalation of drug particles. Their distribution is essential for maximizing the outcomes. Patient-specific computational fluid dynamics (CFD) simulations can be used to optimize these therapies. In this regard, this study focuses on creating a parametric...
journal article 2024
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Ramaekers, M. J.F.G. (author), van der Vlugt, I.B. (author), Westenberg, J. J.M. (author), Perinajová, R. (author), Lamb, H. J. (author), Wildberger, J. E. (author), Kenjeres, S. (author), Schalla, S. (author)
Thoracic aortic aneurysm (TAA) is a local dilation of the thoracic aorta. Although universally used, aneurysm diameter alone is a poor predictor of major complications such as rupture. There is a need for better biomarkers for risk assessment that also reflect the aberrant flow patterns found in TAAs. Furthermore, hypertension is often...
journal article 2024
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Perinajová, R. (author), van Ooij, Pim (author), Kenjeres, S. (author)
A long-time exposure to lack of oxygen (hypoxia) in some regions of the cerebrovascular system is believed to be one of the causes of cerebral neurological diseases. In the present study, we show how a combination of magnetic resonance imaging (MRI) and computational fluid dynamics (CFD) can provide a noninvasive alternative for studying...
journal article 2023
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Perinajová, R. (author), Álvarez-Cuevas, Concepción Borrás (author), Juffermans, Joe (author), Westenberg, Jos (author), Lamb, Hildo (author), Kenjeres, S. (author)
There is a pressing need to establish novel biomarkers to predict the progression of thoracic aortic aneurysm (TAA) dilatation. Aside from hemodynamics, the roles of oxygen (O<sub>2</sub>) and nitric oxide (NO) in TAA pathogenesis are potentially significant. As such, it is imperative to comprehend the relationship between aneurysm presence...
journal article 2023
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Hut, T.Y. (author), Roest, Arno (author), Gaillard, D.H.K. (author), Hazekamp, Mark (author), Van Den Boogaard, Pieter (author), Lamb, Hildo (author), Jongbloed, Monique (author), Rijnberg, Friso (author), Kenjeres, S. (author)
Objectives: Recent evidence suggests that conduits implanted in Fontan patients at the age of 2-4 years become undersized for adulthood. The objective of this study is to use computational fluid dynamic models to evaluate the effect of virtual expansion of the Fontan conduit on haemodynamics and energetics of the total cavopulmonary...
journal article 2023
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Rijnberg, Friso M. (author), van ‘t Hul, Luca C. (author), Hazekamp, Mark G. (author), van den Boogaard, Pieter J. (author), Juffermans, Joe F. (author), Lamb, Hildo J. (author), Kenjeres, S. (author), le Cessie, Saskia (author), Jongbloed, Monique R.M. (author)
OBJECTIVES: To date, it is not known if 16–20-mm extracardiac conduits are outgrown during somatic growth from childhood to adolescence. This study aims to determine total cavopulmonary connection (TCPC) haemodynamics in adolescent Fontan patients at rest and during simulated exercise and to assess the relationship between conduit size and...
journal article 2023
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Wu, X. (author), Saaid, Hicham (author), Voorneveld, J.D. (author), Claessens, Tom (author), Westenberg, Jos J.M. (author), de Jong, N. (author), Bosch, Johan G. (author), Kenjeres, S. (author)
Purpose: Intraventricular blood flow dynamics are associated with cardiac function. Accurate, noninvasive, and easy assessments of hemodynamic quantities (such as velocity, vortex, and pressure) could be an important addition to the clinical diagnosis and treatment of heart diseases. However, the complex time-varying flow brings many...
journal article 2023
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Glavinić, Ivan (author), Muttakin, Imamul (author), Abouelazayem, Shereen (author), Blishchik, A. (author), Stefani, Frank (author), Eckert, Sven (author), Soleimani, Manuchehr (author), Saidani, Iheb (author), Kenjeres, S. (author)
More than 96% of steel in the world is produced via the method of continuous casting. The flow condition in the mould, where the initial solidification occurs, has a significant impact on the quality of steel products. It is important to have timely, and perhaps automated, control of the flow during casting. This work presents a new concept...
journal article 2022
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Rijnberg, Friso M. (author), van der Woude, S.F.S. (author), Hazekamp, Mark G. (author), Van Den Boogaard, Pieter J. (author), Lamb, Hildo J. (author), Terol Espinosa De Los Monteros, Covadonga (author), Kenjeres, S. (author), Karim, Tawab (author), Jongbloed, Monique R.M. (author)
OBJECTIVES: Adequacy of 16-20mm extracardiac conduits for adolescent Fontan patients remains unknown. This study aims to evaluate conduit adequacy using the inferior vena cava (IVC)-conduit velocity mismatch factor along the respiratory cycle. METHODS: Real-time 2D flow MRI was prospectively acquired in 50 extracardiac (16-20mm conduits)...
journal article 2022
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Vesper, J.E. (author), Tietjen, Sebastian C. (author), Chakkingal, M. (author), Kenjeres, S. (author)
In the present study, we analyse individual and combined effects of conductive horizontal walls and conductive fins on the natural convection of air in side heated cavities (SHC). The flow and heat transfer are studied for Rayleigh numbers in the range of 10<sup>4</sup>−−10<sup>9</sup>: Direct Numerical Simulation (DNS) is conducted for the...
journal article 2022
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Cascioli, E. (author), Keijers, S. (author), Van Tichelen, K. (author), Vesper, J.E. (author), Kenjeres, S. (author)
In the present work, we have applied a combined dynamic large-eddy simulation (LES) and direct numerical simulation (DNS) approach for a three-dimensional planar jet in a turbulent forced convection regime (Re = 18000) with a heated co-flow. Results from LES are compared with Reynolds Averaged Navier-Stokes (RANS) simulations and experimental...
journal article 2022
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Blishchik, A. (author), Kenjeres, S. (author)
In the current study, we present a series of numerical simulations describing a turbulent magnetohydrodynamic flow subjected to a transverse magnetic field in a square duct with arbitrary electrically conductive walls. The characteristic flow and electromagnetic non-dimensional parameters (Reynolds and Hartmann number, respectively) were...
journal article 2022
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Jiang, Qian (author), Ren, Feng (author), Wang, Chenglei (author), Wang, Zhaokun (author), Kefayati, Gholamreza (author), Kenjeres, S. (author), Vafai, Kambiz (author), Liu, Yang (author), Tang, Hui (author)
We developed a dedicated computational framework by coupling the lattice-Boltzmann-method (LBM) modeling and the particle-swarm-optimization (PSO) algorithm to search optimal strategies of magnetic nanoparticle (MNP) injection for hyperthermia-based cancer treatment. Two simplified tumor models were considered: a circular model representing...
journal article 2022
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Vesper, J.E. (author), Kenjeres, S. (author), Kleijn, C.R. (author)
In the present study, we propose the use of a light, inert carrier gas to support deposition uniformity and rate in continuous physical vapor deposition, in which closely spaced slots or nozzles are required to achieve a sufficiently high deposition rate. Interaction shocks between the emerging rarefied plumes cause undesired nonuniformities...
journal article 2022
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van As, K. (author), Simons, Bram A. (author), Kleijn, C.R. (author), Kenjeres, S. (author), Bhattacharya, N. (author)
We study how the speckle contrast depends on scatterer velocity, with the goal of further developing laser speckle imaging as a quantitative measurement technique. To that end, we perform interferometric computer simulations on a dilute plug flow. The results of our numerical experiment, that we compare with known analytical expressions to...
journal article 2022
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van As, K. (author), Dellevoet, S. F.L.J. (author), Boterman, J. (author), Kleijn, C.R. (author), Bhattacharya, N. (author), Kenjeres, S. (author)
The disease atherosclerosis causes stenosis inside the patient's arteries, which often eventually turns lethal. Our goal is to detect a stenosis in a non-invasive manner, preferably in an early stage. To that end, we study whether and how laser speckle contrast imaging (LSCI) can be deployed. We start out by using computational fluid dynamics...
journal article 2022
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Blishchik, A. (author), Glavinić, Ivan (author), Wondrak, Thomas (author), van Odyck, Daniel (author), Kenjeres, S. (author)
In the present study, we have performed a series of numerical simulations of the turbulent liquid metal flow in a laboratory-scale setup of the continuous casting. The liquid metal flow was subjected to an external non-uniform magnetic field reproducing a realistic electromagnetic brake (EMBr) effect. The focus of this research was on the...
journal article 2022
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Kenjeres, S. (author), Henry, Frank S. (author), Tsuda, Akira (author)
journal article 2021
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Rijnberg, Friso M. (author), van der Woude, S.F.S. (author), van Assen, Hans C. (author), Juffermans, J.F. (author), Hazekamp, Mark G. (author), Jongbloed, Monique R.M. (author), Kenjeres, S. (author), Lamb, Hildo J. (author), Westenberg, Jos J.M. (author)
Fontan patients require a balanced hepatic blood flow distribution (HFD) to prevent pulmonary arteriovenous malformations. Currently, HFD is quantified by tracking Fontan conduit flow, assuming hepatic venous (HV) flow to be uniformly distributed within the Fontan conduit. However, this assumption may be unvalid leading to inaccuracies in HFD...
journal article 2021
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