Searched for: author%3A%22Kieffer%2C+R.Y.%22
(1 - 5 of 5)
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Oh, J.J. (author), Ammu, S.K. (author), Vriend-Harwig, V.D. (author), Kieffer, R.Y. (author), Dr. Kleiner, F.K. (author), Balasubramanian, S. (author), Karana, E. (author), Masania, K. (author), Aubin-Tam, M.E. (author)
Engineered living materials (ELMs) are a novel class of functional materials that typically feature spatial confinement of living components within an inert polymer matrix to recreate biological functions. Understanding the growth and spatial configuration of cellular populations within a matrix is crucial to predicting and improving their...
journal article 2023
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Amador, G.J. (author), van Dijk, Dennis (author), Kieffer, R.Y. (author), Aubin-Tam, M.E. (author), Tam, D.S.W. (author)
Vital biological processes, such as trafficking, sensing, and motility, are facilitated by cellular lipid membranes, which interact mechanically with surrounding fluids. Such lipid membranes are only a few nanometers thick and composed of a liquid crystalline structure known as the lipid bilayer. Here, we introduce an active, noncontact, two...
journal article 2021
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Dias Ribeiro de Carvalho, V.I. (author), Prabudiansyah, I. (author), Kovacik, Lubomir (author), Chami, Mohamed (author), Kieffer, R.Y. (author), van der Valk, R.A. (author), De Lange, Nick (author), Engel, Andreas (author), Aubin-Tam, M.E. (author)
AAA+ proteases are degradation machines that use ATP hydrolysis to unfold protein substrates and translocate them through a central pore toward a degradation chamber. FtsH, a bacterial membrane-anchored AAA+ protease, plays a vital role in membrane protein quality control. How substrates reach the FtsH central pore is an open key question...
journal article 2020
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Dols Perez, A. (author), Marin Lizarraga, V.M. (author), Amador, G.J. (author), Kieffer, R.Y. (author), Tam, D.S.W. (author), Aubin-Tam, M.E. (author)
Cell lipid membranes are the site of vital biological processes, such as motility, trafficking, and sensing, many of which involve mechanical forces. Elucidating the interplay between such bioprocesses and mechanical forces requires the use of tools that apply and measure piconewton-level forces, e.g., optical tweezers. Here, we introduce the...
journal article 2019
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Marin, Victor (author), Kieffer, R.Y. (author), Padmos, Raymond (author), Aubin-Tam, M.E. (author)
We report a simple, cost-effective, and reproducible method to form free-standing lipid bilayer membranes in microdevices made with Norland Optical Adhesive 81 (NOA81). Surface treatment with either alkylsilane or fluoroalkylsilane enables the self-assembly of stable 1,2-diphytanoyl-sn-glycero-3-phosphocholine 1,2-diphytanoyl-sn-glycero-3...
journal article 2016
Searched for: author%3A%22Kieffer%2C+R.Y.%22
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