Searched for: author%3A%22Koppenol%2C+D.C.%22
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Koppenol, D.C. (author)
Dermal wounds are a significant global problem; although the treatment of these wounds has improved considerably over the last few decades, a treatment still does not result in a complete regeneration of the injured tissue. Instead, the final outcome of the healing process is scar tissue. The material properties of scar tissue are different from...
doctoral thesis 2017
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Koppenol, D.C. (author), Vermolen, F.J. (author)
A continuum hypothesis-based model is developed for the simulation of the (long term) contraction of skin grafts that cover excised burns in order to obtain suggestions regarding the ideal length of splinting therapy and when to start with this therapy such that the therapy is effective optimally. Tissue is modeled as an isotropic,...
journal article 2017
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Koppenol, D.C. (author), Vermolen, F.J. (author), Koppenol-Gonzalez, Gabriela V. (author), Niessen, Frank B. (author), van Zuijlen, Paul P.M. (author), Vuik, Cornelis (author)
A continuum hypothesis-based model is developed for the simulation of the contraction of burns in order to gain new insights into which elements of the healing response might have a substantial influence on this process. Tissue is modeled as a neo-Hookean solid. Furthermore, (myo)fibroblasts, collagen molecules, and a generic signaling molecule...
journal article 2016
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Koppenol, D.C. (author), Vermolen, F.J. (author), Niessen, Frank B. (author), van Zuijlen, Paul P.M. (author), Vuik, Cornelis (author)
A continuum hypothesis-based, biomechanical model is presented for the simulation of the collagen bundle distribution-dependent contraction and subsequent retraction of healing dermal wounds that cover a large surface area. Since wound contraction mainly takes place in the dermal layer of the skin, solely a portion of this layer is included...
journal article 2016
document
Koppenol, D.C. (author), Vermolen, F.J. (author), Niessen, Frank B. (author), van Zuijlen, Paul P.M. (author), Vuik, Cornelis (author)
A continuum hypothesis-based model is presented for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding. Solely the dermal layer of the skin is modeled explicitly and it is modeled as a heterogeneous, isotropic and compressible neo-Hookean solid. With respect to the constituents of the...
journal article 2016
document
Koppenol, D.C. (author)
In this report I present the results from the mathematical analysis of a model neuronal network introduced by Ermentrout and Curtu, extended to two space dimensions. The model can be seen as a simple model of a cortical sheet that describes the firing rate activity of two populations of neurons coupled together, one excitatory that displays...
bachelor thesis 2012
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