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Erol, A. (author), Soloukey, Chagajeg (author), Generowicz, Bastian (author), van Dorp, Nikki (author), Koekkoek, Sebastiaan (author), Kruizinga, P. (author), Hunyadi, Borbala (author)Functional ultrasound (fUS) indirectly measures brain activity by detecting changes in cerebral blood volume following neural activation. Conventional approaches model such functional neuroimaging data as the convolution between an impulse response, known as the hemodynamic response function (HRF), and a binarized representation of the input...journal article 2022
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Erol, A. (author), Soloukey, Chagajeg (author), Generowicz, Bastian (author), van Dorp, Nikki (author), Koekkoek, Sebastiaan (author), Kruizinga, P. (author), Hunyadi, Borbala (author)The original version of this article was revised to update the Figure 8 (panel B) image. The correct image should have a yellow shape as presented below. (Figure presented.). The original article has been corrected.journal article 2022
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Hu, Yuyang (author), Brown, Michael (author), Doğan, D. (author), Leus, G.J.T. (author), Kruizinga, P. (author), Van Der Steen, Antonius F.W. (author), Bosch, Johannes G. (author)We intend to develop an ultrasound compressive imaging device to perform carotid artery (CA) function and flow monitoring/imaging by using just a few single element transducers equipped with spatial coding masks. The spatially unique impulse responses can be exploited in compressive reconstructions. To explore the potential of different...conference paper 2022
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Doğan, D. (author), Kruizinga, P. (author), Bosch, Johannes G. (author), Leus, G.J.T. (author)Ultrasound imaging of the vasculature has major significance for the detection of cardiovascular diseases and cancer. However, limited spatial resolution or long acquisition times of existing techniques limit the visualization of the microvascular structures. Enforcing sparsity in the underlying vasculature as well as exploiting statistical...conference paper 2021
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van der Meulen, P.Q. (author), Kruizinga, P. (author), Bosch, Johannes G. (author), Leus, G.J.T. (author)We study the design of a coding mask for pulse-echo ultrasound imaging. We are interested in the scenario of a single receiving transducer with an aberrating layer, or ‘mask,’ in front of the transducer's receive surface, with a separate co-located transmit transducer. The mask encodes spatial measurements into a single output signal, containing...journal article 2020
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Erol, A. (author), Eyndhoven, Simon Van (author), Koekkoek, Sebastiaan (author), Kruizinga, P. (author), Hunyadi, Borbala (author)Functional ultrasound (fUS) is an exciting new neuroimaging technique that is able to record brain activity similar to functional magnetic resonance imaging, yet with higher spatiotemporal resolution and at lower cost. We consider the problem of jointly estimating the underlying neural sources and the hemodynamic response function (HRF) from fUS...conference paper 2020
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van der Meulen, P.Q. (author), Coutino, Mario (author), Kruizinga, P. (author), Bosch, J.G. (author), Leus, G.J.T. (author)We consider the scenario of finding the transfer function of an aberrating layer in front of an ultrasound array. We are interested in blindly estimating this transfer function without prior knowledge of the unknown ultrasound sources or ultrasound contrast image. The algorithm gives an exact solution if the matrix representing the aberration...conference paper 2020
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Iskander-Rizk, Sophinese (author), Kruizinga, P. (author), Beurskens, Robert (author), Springeling, Geert (author), Mastik, Frits (author), de Groot, N.M.S. (author), Knops, Paul (author), van der Steen, A.F.W. (author), van Soest, Gijs (author)In interventional electrophysiology, catheter-based radiofrequency (RF) ablation procedures restore cardiac heart rhythm by interrupting aberrant conduction paths. Real-time feedback on lesion formation and post-treatment lesion assessment could overcome procedural challenges related to ablation of underlying structures and lesion gaps. This...journal article 2019
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van der Meulen, P.Q. (author), Kruizinga, P. (author), Bosch, Johannes G. (author), Leus, G.J.T. (author)We consider a model-based ultrasound imaging scenario using a single transducer with a coding mask, and assume that the pulse-echo model is erroneously estimated, resulting in decreased imaging performance. Although the pulse-echo Green's function to each pixel has to be measured to obtain a good model, typically only forward-field...conference paper 2019
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Kang, E. (author), Ding, Q. (author), Shabanimotlagh, M. (author), Kruizinga, P. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, J.W. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)This paper presents an ultrasound transceiver application-specific integrated circuit (ASIC) designed for 3-D ultrasonic imaging of the carotid artery. This application calls for an array of thousands of ultrasonic transducer elements, far exceeding the number of channels of conventional imaging systems. The 3.6 x 6.8 mm² ASIC...journal article 2018
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Iskander-Rizk, Sophinese (author), Kruizinga, P. (author), Van Der Steen, Antonius F.W. (author), van Soest, G. (author), van der Steen, A.F.W. (author)Catheter-based radiofrequency ablation for atrial fibrillation has long-term success in 60-70% of cases. A better assessment of lesion quality, depth, and continuity could improve the procedure’s outcome. We investigate here photoacoustic contrast between ablated and healthy atrial-wall tissue in vitro in wavelengths spanning from 410 nm to...journal article 2018
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van der Meulen, P.Q. (author), Kruizinga, P. (author), Bosch, J.G. (author), Leus, G.J.T. (author)We study the optimal design of an aperture coding mask, and the optimal sensing positions of a single ultrasound sensor with a scanning configuration. In previous works, we have shown that 3D ultrasound imaging is possible using a randomly shaped coding mask with randomly chosen sensing positions. Here we propose an optimization algorithm for...conference paper 2018
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Janjic, Jovana (author), Kruizinga, P. (author), van der Meulen, P.Q. (author), Springeling, Geert (author), Mastik, Frits (author), Leus, G.J.T. (author), Bosch, Johan G. (author), van der Steen, A.F.W. (author), van Soest, G. (author)We present a form of acoustic microscopy, called Structured Ultrasound Microscopy (SUM). It creates a volumetric image by recording reflected echoes of ultrasound waves with a structured phase front using a moving single-element transducer and computational reconstruction. A priori knowledge of the acoustic field produced by the single...journal article 2018
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Bera, D. (author), Van Den Adel, Franc (author), Radeljic-Jakic, Nikola (author), Lippe, Boris (author), Soozande, M. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), Kruizinga, P. (author), Daeichin, V. (author), Vos, H.J. (author), van der Steen, A.F.W. (author), Bosch, Johan G. (author), de Jong, N. (author)We describe a 3-D multiline parallel beamforming scheme for real-time volumetric ultrasound imaging using a prototype matrix transesophageal echocardiography probe with diagonally diced elements and separated transmit and receive arrays. The elements in the smaller rectangular transmit array are directly wired to the ultrasound system. The...journal article 2018
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van der Meulen, P.Q. (author), Kruizinga, P. (author), Bosch, Johan G. (author), Leus, G.J.T. (author)High quality three dimensional ultrasound imaging is typically attained by increasing the amount of sensors, resulting in complex hardware. Compressing measurements before sensing addresses this problem, and could enable new clinical applications. We have developed an analogue compression technique, by positioning a plastic coding mask in...conference paper 2018
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Generowicz, B.S. (author), Leus, G.J.T. (author), Tbalvandanv, S. Soloukey (author), Van Hoogstraten, W. S. (author), Strvdis, C. (author), Bosch, J. G. (author), van der Steen, A.F.W. (author), De Zeeuwl, C. I. (author), Koekkoek, S. K.E. (author), Kruizinga, P. (author)Current methods to measure blood flow using ultrafast Doppler imaging often make use of a Singular Value Decomposition (SVD). The SVD has been shown to be an effective way to remove clutter signals associated with slow moving tissue. Conventionally, the SVD is calculated from an ensemble of frames, after which the first dominant eigenvectors...conference paper 2018
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Kruizinga, P. (author), van der Meulen, P.F. (author), Fedjajevs, A. (author), Mastik, F (author), Springeling, Geert (author), de Jong, N. (author), Bosch, J.G. (author), Leus, G.J.T. (author)Three-dimensional ultrasound is a powerful imaging technique, but it requires thousands of sensors and complex hardware. Very recently, the discovery of compressive sensing has shown that the signal structure can be exploited to reduce the burden posed by traditional sensing requirements. In this spirit, we have designed a simple ultrasound...journal article 2017
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Lajoinie, Guillaume (author), Lee, Jeong Yu (author), Owen, Joshua (author), Kruizinga, P. (author), de Jong, N. (author), Van Soest, Gijs (author), Stride, Eleanor (author), Versluis, Michel (author)Photoacoustic (PA) imaging offers several attractive features as a biomedical imaging modality, including excellent spatial resolution and functional information such as tissue oxygenation. A key limitation, however, is the contrast to noise ratio that can be obtained from tissue depths greater than 1-2 mm. Microbubbles coated with an...journal article 2017
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Lajoinie, Guillaume (author), Linnartz, Erik (author), Kruizinga, P. (author), de Jong, N. (author), Stride, Eleanor (author), Van Soest, Gijs (author), Versluis, Michel (author)Microbubbles are used to enhance the contrast in ultrasound imaging. When coated with an optically absorbing material, these bubbles can also provide contrast in photoacoustic imaging. This multimodal aspect is of pronounced interest to the field of medical imaging. The aim of this paper is to provide a theoretical framework to describe the...journal article 2017
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Kruizinga, P. (author), Springeling, G. (author), Van Soest, G. (author), Van der Steen, A.F.W. (author), De Jong, N. (author), Robertus, J.L. (author), Van der Lugt, A. (author)We introduce a method for photoacoustic imaging of the carotid artery, tailored toward detection of lipid-rich atherosclerotic lesions. A common human carotid artery was obtained at autopsy, embedded in a neck mimicking phantom and imaged with a multimodality imaging system using interstitial illumination. Light was delivered through a 1.25-mm...journal article 2014
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