Searched for: author%3A%22Loozen%2C+G.B.%22
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Loozen, G.B. (author)
Optofluidic lab-on-a-chips (LOCs) employing a dual-waveguide trap for optical trapping and Raman spectroscopy have proven to be attractive and potent tools for high throughput chemical fingerprinting of bio-particles for disease diagnosis. Among the relevant bio-particles are extracellular vesicles (EVs) which a been proven through recent...
doctoral thesis 2023
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Loozen, G.B. (author), Karuna, A. (author), Rafiee Fanood, M.M. (author), Schreuder, Erik (author), Caro-Schuurman, J. (author)
We realized integrated photonics multi-waveguide devices for optical trapping and Raman spectroscopy of particles in a fluid. In these devices, multiple beams directed towards the device center lead to a local field enhancement around this center and thus counteract the effect of light concentration near the facets, which is a disadvantage of...
journal article 2020
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Rikkert, L. G. (author), Beekman, P. (author), Caro-Schuurman, J. (author), Coumans, F. A.W. (author), Enciso-Martinez, A. (author), Jenster, G. (author), Le Gac, S. (author), Lee, W. (author), Loozen, G.B. (author)
Extracellular vesicles (EVs) have great potential as biomarkers since their composition and concentration in biofluids are disease state dependent and their cargo can contain disease-related information. Large tumor-derived EVs (tdEVs, >1μm) in blood from cancer patients are associated with poor outcome, and changes in their number can be...
journal article 2020
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Loozen, G.B. (author), Caro-Schuurman, J. (author)
The application of on-chip optical trapping and Raman spectroscopy using a dual-waveguide trap has so far been limited to relatively big synthetic and biological particles (e.g., polystyrene beads and blood cells). Here, from simulations, we present the capabilities of dual-waveguide traps built from composite SiO<sub>2</sub>-Si<sub>3</sub>N...
journal article 2018
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Nemati, M. (author), Loozen, G.B. (author), Van der Wekken, N. (author), Van de Belt, G. (author), Urbach, H.P. (author), Bhattacharya, N. (author), Kenjeres, S. (author)
A preliminary comparative measurement between particle imaging velocimetry (PIV) and laser speckle contrast analysis (LASCA) to study pulsatile flow using ventricular assist device in a patient-specific carotid artery phantom is reported. These full-field optical techniques have both been used to study flow and extract complementary parameters....
journal article 2015
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