Searched for: author%3A%22Mastik%2C+Frits%22
(1 - 12 of 12)
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Li, H. (author), Li, X. (author), Collado Lara, G. (author), Lattwein, K.R. (author), Mastik, Frits (author), Beurskens, Robert (author), van der Steen, A.F.W. (author), Verweij, M.A. (author), de Jong, N. (author), Kooiman, Klazina (author)
Ultrasound contrast-mediated medical imaging and therapy both rely on the dynamics of micron- and nanometer-sized ultrasound cavitation nuclei, such as phospholipid-coated microbubbles and phase-change droplets. Ultrasound cavitation nuclei respond non-linearly to ultrasound on a nanosecond time scale that necessitates the use of ultra-high...
journal article 2023
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Zangabad, Reza Pakdaman (author), Bosch, Johan G. (author), Mastik, Frits (author), Beurskens, Robert H.S.H. (author), Henneken, Vincent A. (author), Weekamp, Johannes W. (author), van der Steen, A.F.W. (author), van Soest, Gijs (author)
Intravascular ultrasound (IVUS) is a well-established diagnostic method that provides images of the vessel wall and atherosclerotic plaques. We investigate the potential for phased-array IVUS utilizing coded excitation (CE) for improving the penetration depth and image signal-to-noise ratio (SNR). It is realized on a new experimental...
journal article 2021
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Beekers, D.I. (author), Vegter, Merel (author), Lattwein, Kirby R. (author), Mastik, Frits (author), Beurskens, Robert (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)
Ultrasound insonification of microbubbles can locally increase vascular permeability to enhance drug delivery. To control and optimize the therapeutic potential, we need to better understand the underlying biological mechanisms of the drug delivery pathways. The aim of this in vitro study was to elucidate the microbubble-endothelial cell...
journal article 2020
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Generowicz, B.S. (author), Verhoef, Luuk (author), Mastik, Frits (author), Dijkhuizen, Stefanie (author), van Dorp, Nikki (author), Voorneveld, Jason (author), Bosch, Johannes (author), Kumar, Karishma (author), Leus, G.J.T. (author)
Power Doppler (PD) imaging has become a staple in high frame rate ultrasound imaging due to its ability to image small vessels and slow-moving flows, such as in the case of imaging blood flow in the brain. Alternatively, color Doppler (CD) can be used to determine the one-dimensional directional information of the blood scatterers. This can help...
conference paper 2020
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Beekers, D.I. (author), Mastik, Frits (author), Beurskens, Robert (author), Tang, Phoei Ying (author), Vegter, Merel (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)
Ultrasound insonification of microbubbles can locally enhance drug delivery, but the microbubble–cell interaction remains poorly understood. Because intracellular calcium (Ca<sub>i</sub> <sup>2+</sup>) is a key cellular regulator, unraveling the Ca<sub>i</sub> <sup>2+</sup> fluctuations caused by an oscillating microbubble provides crucial...
journal article 2020
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Iskander-Rizk, Sophinese (author), Kruizinga, P. (author), Beurskens, Robert (author), Springeling, Geert (author), Mastik, Frits (author), de Groot, N.M.S. (author), Knops, Paul (author), van der Steen, A.F.W. (author), van Soest, Gijs (author)
In interventional electrophysiology, catheter-based radiofrequency (RF) ablation procedures restore cardiac heart rhythm by interrupting aberrant conduction paths. Real-time feedback on lesion formation and post-treatment lesion assessment could overcome procedural challenges related to ablation of underlying structures and lesion gaps. This...
journal article 2019
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Lajoinie, Guillaume (author), Luan, Ying (author), Gelderblom, Erik (author), Dollet, Benjamin (author), Mastik, Frits (author), Dewitte, Heleen (author), Lentacker, Ine (author), de Jong, N. (author), Versluis, Michel (author)
journal article 2018
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Janjic, Jovana (author), Kruizinga, P. (author), van der Meulen, P.Q. (author), Springeling, Geert (author), Mastik, Frits (author), Leus, G.J.T. (author), Bosch, Johan G. (author), van der Steen, A.F.W. (author), van Soest, G. (author)
We present a form of acoustic microscopy, called Structured Ultrasound Microscopy (SUM). It creates a volumetric image by recording reflected echoes of ultrasound waves with a structured phase front using a moving single-element transducer and computational reconstruction. A priori knowledge of the acoustic field produced by the single...
journal article 2018
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Wu, Min (author), Springeling, Geert (author), Lovrak, M. (author), Mastik, Frits (author), Iskander-Rizk, Sophinese (author), Wang, Tianshi (author), Van Beusekom, Heleen M.M. (author), van der Steen, A.F.W. (author), van Soest, G. (author)
Lipid deposition can be assessed with combined intravascular photoacoustic/ultrasound (IVPA/US) imaging. To date, the clinical translation of IVPA/US imaging has been stalled by a low imaging speed and catheter complexity. In this paper, we demonstrate imaging of lipid targets in swine coronary arteries in vivo, at a clinically useful frame...
journal article 2017
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Kooiman, Klazina (author), van Rooij, Tom (author), Qin, Bin (author), Mastik, Frits (author), Vos, H.J. (author), Versluis, Michel (author), Klibanov, Alexander L. (author), de Jong, N. (author), Villanueva, Flordeliza S. (author), Chen, Xucai (author)
Acoustic behavior of lipid-coated microbubbles has been widely studied, which has led to several numerical microbubble dynamics models that incorporate lipid coating behavior, such as buckling and rupture. In this study we investigated the relationship between micro-bubble acoustic and lipid coating behavior on a nanosecond scale by using...
journal article 2017
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Luan, Ying (author), Renaud, Guillaume (author), Raymond, Jason L. (author), Segers, Tim (author), Lajoinie, Guillaume (author), Beurskens, Robert (author), Mastik, Frits (author), Kokhuis, Tom J A (author), van der Steen, A.F.W. (author), Versluis, Michel (author), de Jong, N. (author)
In this study we present a combined optical sizing and acoustical characterization technique for the study of the dynamics of single freely-floating ultrasound contrast agent microbubbles exposed to long burst ultrasound excitations up to the milliseconds range. A co-axial flow device was used to position individual microbubbles on a...
journal article 2016
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Kruizinga, P. (author), Mastik, Frits (author), van den Oord, Stijn C.H. (author), Schinkel, Arend F.L. (author), Bosch, Johannes G. (author), de Jong, N. (author), van Soest, G. (author), van der Steen, A.F.W. (author)
The carotid artery (CA) is central to cardiovascular research, because of the clinical relevance of CA plaques as culprits of stroke and the accessibility of the CA for cardiovascular screening. The viscoelastic state of this artery, essential for clinical evaluation, can be assessed by observing arterial deformation in response to the...
journal article 2014
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