Searched for: author%3A%22Nijsen%2C+J.F.W.%22
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Vente, M.A.D. (author), De Wit, T.C. (author), Van den Bosch, M.A.A.J. (author), Bult, W. (author), Seevinck, P.R. (author), Zonnenberg, B.A. (author), De Jong, H.W.A.M. (author), Krijger, G.C. (author), Bakker, C.J.G. (author), Van Het Schip, A.D. (author), Nijsen, J.F.W. (author)
journal article 2009
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Vente, M.A.D. (author), Nijsen, J.F.W. (author), De Roos, R. (author), Van Steenbergen, M.J. (author), Kaaijk, C.N.J. (author), Koster-Ammerlaan, M.J.J. (author), De Leege, P.F.A. (author), Hennink, W.E. (author), Van het Schip, A.D. (author), Krijger, G.C. (author)
Poly(L-lactic acid) microspheres loaded with holmium-166 acetylacetonate (166Ho-PLLA-MS) are a novel microdevice for intra-arterial radioembolization in patients with unresectable liver malignancies. The neutron activation in a nuclear reactor, in particular the gamma heating, damages the 166Ho-PLLA-MS. The degree of damage is dependent on the...
journal article 2009
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Vente, M.A.D. (author), Nijsen, J.F.W. (author), De Wit, T.C. (author), Seppenwoolde, J.H. (author), Krijger, G.C. (author), Seevinck, P.R. (author), Huisman, A. (author), Zonneneberg, B.A. (author), Van den Ingh, T.S.G.A.M. (author), Van het Schip, A.D. (author)
Purpose The aim of this study is to evaluate the toxicity of holmium-166 poly(l-lactic acid) microspheres administered into the hepatic artery in pigs. Methods Healthy pigs (20–30 kg) were injected into the hepatic artery with holmium-165-loaded microspheres (165HoMS; n?=?5) or with holmium-166-loaded microspheres (166HoMS; n?=?13). The...
journal article 2008
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Zielhuis, S.W. (author), Seppenwoolde, J.H. (author), Mateus, V.A.P. (author), Bakker, C.J.G. (author), Krijger, G.C. (author), Storm, G. (author), Zonnenberg, B.A. (author), Van het Schip, A.D. (author), Koning, G.A. (author), Nijsen, J.F.W. (author)
Many advanced molecular imaging agents are currently being investigated preclinically. Especially, liposomes, have proven to be very promising carrier systems for diagnostic agents for use in single-photon emission computed tomography (SPECT) or magnetic resonance imaging (MRI), as well as for therapeutic agents to treat diseases such as cancer....
journal article 2006
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Bult, W. (author), Seevinck, P.R. (author), Krijger, G.C. (author), Visser, T. (author), Kroon-Batenburg, L.M.J. (author), Bakker, C.J.G. (author), Hennink, W.E. (author), Van het Schip, A.D. (author), Nijsen, J.F.W. (author)
Purpose The aim of this study was to develop microspheres with an ultra high holmium content which can be neutron activated for radioablation of malignancies. These microspheres are proposed to be delivered selectively through either intratumoral injections into solid tumors or administered via an intravascularly placed catheter. Methods...
journal article
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