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Nika, Ioanna (author)
Lineage abundance estimation of SARS-CoV-2 in wastewater is a technique that aims to monitor the lineage prevalence in communities and help contain the COVID-19 pandemic. Lineages are collections of closely related mutants of a virus. It is suggested that the genome sequences of lineages differ across the globe due to random mutations or...
bachelor thesis 2022
Baaijens, J.A. (author), Zulli, Alessandro (author), Ott, Isabel M. (author), Nika, Ioanna (author), van der Lugt, Mart J. (author), Petrone, Mary E. (author), Alpert, Tara (author), Fauver, Joseph R. (author), Kalinich, Chaney C. (author)
Effectively monitoring the spread of SARS-CoV-2 mutants is essential to efforts to counter the ongoing pandemic. Predicting lineage abundance from wastewater, however, is technically challenging. We show that by sequencing SARS-CoV-2 RNA in wastewater and applying algorithms initially used for transcriptome quantification, we can estimate...
journal article 2022