First in situ TOF-PET study using digital photon counters for proton range verification

Positron emission tomography (PET) is the imaging modality most extensively tested for treatment monitoring in particle therapy. Optimal use of PET in proton therapy requires in situ acquisition of the relatively strong ¹⁵O signal due to its relatively short half-life (∼2 min) and high oxygen content in biological tissues, enabling...

Time-resolved imaging of prompt-gamma rays for proton range verification using a knife-edge slit camera based on digital photon counters

Proton range monitoring may facilitate online adaptive proton therapy and improve treatment outcomes. Imaging of proton-induced prompt gamma (PG) rays using a knife-edge slit collimator is currently under investigation as a potential tool for real-time proton range monitoring. A major challenge in collimated PG imaging is the suppression of...

Development of a Compton Camera for Online Range Monitoring of Laser-Accelerated Proton Beams via Prompt-Gamma Detection

Presently large efforts are conducted in Munich towards the development of proton beams for bio-medical applications, generated via the technique of particle acceleration from high-power, short-pulse lasers. While so far mostly offline diagnostics tools are used in this context, we aim at developing a reliable and accurate online range...