Searched for: author%3A%22Ruers%2C+Theo+J.M.%22
(1 - 11 of 11)
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van der Stel, Stefan D. (author), Lai, Marco (author), Groen, Harald C. (author), Witteveen, Mark (author), Kuhlmann, Koert F.D. (author), Grotenhuis, Brechtje A. (author), Kok, Niels F.M. (author), van Gastel, Mark (author), Hendriks, B.H.W. (author), Ruers, Theo J.M. (author)
Introduction: Anastomotic leakage after gastrointestinal surgery has a high impact on patient's quality of life and its origin is associated with inadequate perfusion. Imaging photoplethysmography (iPPG) is a noninvasive imaging technique that measures blood-volume changes in the microvascular tissue bed and detects changes in tissue...
journal article 2023
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Geldof, Freija (author), Dashtbozorg, Behdad (author), Hendriks, B.H.W. (author), Sterenborg, Henricus J.C.M. (author), Ruers, Theo J.M. (author)
During oncological surgery, it can be challenging to identify the tumor and establish adequate resection margins. This study proposes a new two-layer approach in which diffuse reflectance spectroscopy (DRS) is used to predict the top layer thickness and classify the layers in two-layered phantom and animal tissue. Using wavelet-based and peak...
journal article 2022
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Lai, Marco (author), van der Stel, Stefan D. (author), Groen, Harald C. (author), van Gastel, Mark (author), Kuhlmann, Koert F.D. (author), Ruers, Theo J.M. (author), Hendriks, B.H.W. (author)
Surgical excision is the golden standard for treatment of intestinal tumors. In this surgical procedure, inadequate perfusion of the anastomosis can lead to postoperative complications, such as anastomotic leakages. Imaging photoplethysmography (iPPG) can potentially provide objective and real-time feedback of the perfusion status of tissues....
journal article 2022
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de Boer, Lisanne L. (author), Kho, Esther (author), Van de Vijver, Koen K. (author), Vranken Peeters, Marie Jeanne T.F.D. (author), van Duijnhoven, Frederieke (author), Hendriks, B.H.W. (author), Sterenborg, Henricus J.C.M. (author), Ruers, Theo J.M. (author)
Background: Although the incidence of positive resection margins in breast-conserving surgery has decreased, both incomplete resection and unnecessary large resections still occur. This is especially the case in the surgical treatment of ductal carcinoma in situ (DCIS). Diffuse reflectance spectroscopy (DRS), an optical technology based on...
journal article 2021
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Geldof, Freija (author), Jong, Lynn-Jade (author), Dashtbozorg, Behdad (author), Hendriks, B.H.W. (author), Sterenborg, Henricus J.C.M. (author), Ruers, Theo J.M. (author)
Establishing adequate resection margins during colorectal cancer surgery is challenging. Currently, in up to 30% of the cases the tumor is not completely removed, which emphasizes the lack of a real-time tissue discrimination tool that can assess resection margins up to multiple millimeters in depth. Therefore, we propose to combine spectral...
conference paper 2021
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Baltussen, Elisabeth J.M. (author), Brouwer de Koning, Susan G. (author), Hendriks, B.H.W. (author), Jóźwiak, Katarzyna (author), Sterenborg, Henricus J.C.M. (author), Ruers, Theo J.M. (author)
In vivo data acquisition using fiberoptic diffuse reflectance spectroscopy (DRS) is more complicated and less controlled compared to ex vivo data acquisition. It would be of great benefit if classifiers for in vivo tissue discrimination based on DRS could be trained on data obtained ex vivo. In this study, in vivo and ex vivo DRS measurements...
journal article 2019
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De Boer, Lisanne L. (author), Kho, Esther (author), Józwiak, Katarzyna (author), Van De Vijver, Koen K. (author), Vrancken Peeters, Marie Jeanne T.F.D. (author), Van Duijnhoven, Frederieke (author), Hendriks, B.H.W. (author), Sterenborg, Henricus J.C.M. (author), Ruers, Theo J.M. (author)
Diffuse reflectance spectroscopy (DRS) can discriminate different tissue types based on optical characteristics. Since this technology has the ability to detect tumor tissue, several groups have proposed to use DRS for margin assessment during breast-conserving surgery for breast cancer. Nowadays, an increasing number of patients with breast...
journal article 2019
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Langhout, Gerrit C. (author), Kuhlmann, Koert F.D. (author), Schreuder, Pim (author), Bydlon, Torre (author), Smeele, Ludi E. (author), van den Brekel, Michiel W.M. (author), Sterenborg, Henricus J.C.M. (author), Hendriks, B.H.W. (author), Ruers, Theo J.M. (author)
Background: Careful identification of nerves during head and neck surgery is essential to prevent nerve damage. Currently, nerves are identified based on anatomy and appearance, optionally combined with electromyography (EMG). In challenging cases, nerve damage is reported in up to 50%. Recently, optical techniques, like diffuse reflectance...
journal article 2018
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De Boer, Lisanne L. (author), Bydlon, Torre M. (author), Van Duijnhoven, Frederieke (author), Vranken Peeters, Marie Jeanne T.F.D. (author), Loo, Claudette E. (author), Winter-Warnars, Gonneke A.O. (author), Sanders, Joyce (author), Sterenborg, Henricus J.C.M. (author), Hendriks, B.H.W. (author), Ruers, Theo J.M. (author)
Background: Breast cancer surgeons struggle with differentiating healthy tissue from cancer at the resection margin during surgery. We report on the feasibility of using diffuse reflectance spectroscopy (DRS) for real-time in vivo tissue characterization. Methods: Evaluating feasibility of the technology requires a setting in which...
journal article 2018
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Brouwer de Koning, Susan G. (author), Baltussen, Elisabeth J.M. (author), Karakullukcu, M. Baris (author), Dashtbozorg, Behdad (author), Smit, Laura A. (author), Dirven, Richard (author), Hendriks, B.H.W. (author), Sterenborg, Henricus J.C.M. (author), Ruers, Theo J.M. (author)
This ex-vivo study evaluates the feasibility of diffuse reflectance spectroscopy (DRS) for discriminating tumor from healthy tissue, with the aim to develop a technology that can assess resection margins for the presence of tumor cells during oral cavity cancer surgery. Diffuse reflectance spectra were acquired on fresh surgical specimens...
journal article 2018
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Baltussen, Elisabeth J.M. (author), Snaebjornsson, Petur (author), De Koning, Susan G.Brouwer (author), Sterenborg, Henricus J.C.M. (author), Aalbers, Arend G.J. (author), Kok, Niels (author), Beets, Geerard L. (author), Hendriks, B.H.W. (author), Kuhlmann, Koert F.D. (author), Ruers, Theo J.M. (author)
Colorectal surgery is the standard treatment for patients with colorectal cancer. To overcome two of the main challenges, the circumferential resection margin and postoperative complications, real-time tissue assessment could be of great benefit during surgery. In this ex vivo study, diffuse reflectance spectroscopy (DRS) was used to...
journal article 2017
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