Searched for: author%3A%22Schlicker%2C+A.%22
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Schlicker, A (author), Michaut, Magali (author), Rahman, Rubayte (author), Wessels, L.F.A. (author)
Although large-scale efforts for molecular profiling of cancer samples provide multiple data types for many samples, most approaches for finding candidate cancer genes rely on somatic mutations and DNA copy number only. We present a new method, OncoScape, which exploits five complementary data types across 11 cancer types to identify new...
journal article 2016
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Roepman, P. (author), Schlicker, A. (author), Tabernero, J. (author), Majewski, I. (author), Tian, S. (author), Moreno, V. (author), Snel, M.H. (author), Chresta, C.M. (author), Rosenberg, R. (author), Nitsche, U. (author), Macarulla, T. (author), Capella, G. (author), Salazar, R. (author), Orphanides, G. (author), Wessels, L.F.A. (author), Bernards, R. (author), Simon, I.M. (author)
In most colorectal cancer (CRC) patients, outcome cannot be predicted because tumors with similar clinicopathological features can have differences in disease progression and treatment response. Therefore, a better understanding of the CRC biology is required to identify those patients who will benefit from chemotherapy and to find a more...
journal article 2013
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Schlicker, A. (author), Beran, G. (author), Chresta, C.M. (author), McWalter, G. (author), Pritchard, A. (author), Weston, S. (author), Runswick, S. (author), Davenport, S. (author), Heathcote, K. (author), Alferez Castro, D. (author), Orphanides, G. (author), French, T. (author), Wessels, L.F.A. (author)
Background Colorectal cancer (CRC) is a heterogeneous and biologically poorly understood disease. To tailor CRC treatment, it is essential to first model this heterogeneity by defining subtypes of patients with homogeneous biological and clinical characteristics and second match these subtypes to cell lines for which extensive pharmacological...
journal article 2012