- document
-
van’t Veld, Ronald C. (author), Flux, Eline (author), van Oorschot, Wieneke (author), Schouten, A.C. (author), van der Krogt, Marjolein M. (author), van der Kooij, H. (author), Vos-van der Hulst, Marije (author), Keijsers, Noël L.W. (author), van Asseldonk, Edwin H.F. (author)Background: Spasticity, i.e. stretch hyperreflexia, increases joint resistance similar to symptoms like hypertonia and contractures. Botulinum neurotoxin-A (BoNT-A) injections are a widely used intervention to reduce spasticity. BoNT-A effects on spasticity are poorly understood, because clinical measures, e.g. modified Ashworth scale (MAS),...journal article 2023
- document
-
van den Berg, Boudewijn (author), Manoochehri, M. (author), Schouten, A.C. (author), van der Helm, F.C.T. (author), Buitenweg, Jan R. (author)Recent studies have established the presence of nociceptive steady-state evoked potentials (SSEPs), generated in response to thermal or intra-epidermal electric stimuli. This study explores cortical sources and generation mechanisms of nociceptive SSEPs in response to intra-epidermal electric stimuli. Our method was to stimulate healthy...journal article 2022
- document
-
van de Ruit, M.L. (author), Mugge, W. (author), Schouten, A.C. (author)Careful control of joint impedance, or dynamic joint stiffness, is crucial for successful performance of movement. Time-varying system identification (TV-SysID) enables quantification of joint impedance during movement. Several TV-SysID methods exist, but have never been systematically compared. Here, we simulate time-varying joint behavior...book chapter 2022
- document
-
van ’t Veld, Ronald C. (author), Fricke, S. S. (author), Prieto, Ander Vallinas (author), Keemink, Arvid Q.L. (author), Schouten, A.C. (author), van der Kooij, H. (author), van Asseldonk, E. H.F. (author)Joint impedance plays an important role in postural control and movement. However, current experimental knowledge on lower limb impedance during gait is limited to the ankle joint. We designed the LOwer limb PERturbator (LOPER) aimed to assess knee and hip joint impedance during gait. The LOPER applies force perturbations with a 39 Hz...book chapter 2022
- document
-
Cavallo, Gaia (author), Cop, Christopher P. (author), Sartori, M. (author), Schouten, A.C. (author), Lataire, John (author)Joint impedance is a common way of representing human joint dynamics. Since ankle joint impedance varies within the gait cycle, time-varying system identification techniques can be used to estimate it. Commonly, time-varying system identification techniques assume repeatably of joint impedance over cyclic motions, without taking into...book chapter 2022
- document
-
Cop, Christopher P. (author), Schouten, A.C. (author), Koopman, Bart F.J.M. (author), Sartori, M. (author)Quantifying human joint stiffness in vivo during movement remains challenging. Well established stiffness estimation methods include system identification and the notion of quasi-stiffness, with experimental and conceptual limitations, respectively. Joint stiffness computation via biomechanical models is an emerging solution to overcome such...book chapter 2022
- document
-
Cop, Christopher P. (author), Schouten, A.C. (author), Koopman, Bart (author), Sartori, Massimo (author)The simultaneous modulation of joint torque and stiffness enables humans to perform large repertoires of movements, while versatilely adapting to external mechanical demands. Multi-muscle force control is key for joint torque and stiffness modulation. However, the inability to directly measure muscle force in the intact moving human prevents...journal article 2022
- document
-
Sharifi, S. (author), Luft, F. (author), de Boer, L. (author), Buijink, A. W.G. (author), Mugge, W. (author), Schouten, A.C. (author), Heida, T. (author), Bour, L. J. (author), van Rootselaar, A. F. (author)Tremor is thought to be an effect of oscillatory activity within the sensorimotor network. To date, the underlying pathological brain networks are not fully understood. Disentangling tremor activity from voluntary motor output and sensorimotor feedback systems is challenging. To better understand the intrinsic sensorimotor fingerprint...journal article 2022
- document
-
van der Cruijsen, J. (author), Dooren, R.F. (author), Schouten, A.C. (author), Oostendorp, Thom F. (author), Frens, Maarten A. (author), Ribbers, G.M. (author), van der Helm, F.C.T. (author), Kwakkel, Gert (author), Selles, R.W. (author)Transcranial direct current stimulation (tDCS) is a promising tool to improve and speed up motor rehabilitation after stroke, but inconsistent clinical effects refrain tDCS from clinical implementation. Therefore, this study aimed to assess the need for individualized tDCS configurations in stroke, considering interindividual variability in...journal article 2022
- document
-
van der Kooij, H. (author), Fricke, Simone S. (author), Van 't Veld, Ronald C. (author), Prieto, Ander Vallinas (author), Keemink, Arvid Q.L. (author), Schouten, A.C. (author), Van Asseldonk, Edwin H.F. (author)Knowledge on joint impedance during walking in various conditions is relevant for clinical decision-making and the development of robotic gait trainers, leg prostheses, leg orthotics and wearable exoskeletons. Whereas ankle impedance during walking has been experimentally assessed, knee and hip joint impedance during walking have not been...journal article 2022
- document
-
Cop, Christopher P. (author), Cavallo, Gaia (author), van'T Veld, Ronald C. (author), Koopman, Bart F.J.M. (author), Lataire, John (author), Schouten, A.C. (author), Sartori, Massimo (author)In vivo joint stiffness estimation during time-varying conditions remains an open challenge. Multiple communities, e.g. system identification and biomechanics, have tackled the problem from different perspectives and using different methods, each of which entailing advantages and limitations, often complementary. System identification...review 2021
- document
-
van de Ruit, M.L. (author), Mugge, W. (author), Cavallo, Gaia (author), Lataire, John (author), Ludvig, Daniel (author), Schouten, A.C. (author)Accurate and swift tuning of joint impedance is crucial to perform movement and interaction with our environment. Time-varying system identification enables quantification of joint impedance during movement. Many methods have been developed over the years, each with their own mathematical approach and underlying assumptions. Yet, for the...journal article 2021
- document
-
van Kordelaar, J. (author), van de Ruit, M.L. (author), Solis Escalante, T. (author), Aerden, Leo A.M. (author), Meskers, Carel G.M. (author), van Wegen, Erwin E.H. (author), Schouten, A.C. (author), Kwakkel, Gert (author), van der Helm, F.C.T. (author)Background: Proprioception is important for regaining motor function in the paretic upper extremity after stroke. However, clinical assessments of proprioception are subjective and require verbal responses from the patient to applied proprioceptive stimuli. Cortical responses evoked by robotic wrist perturbations and measured by...journal article 2021
- document
-
van 't Veld, Ronald (author), Flux, Eline (author), Schouten, A.C. (author), van der Krogt, Marjolein (author), van der Kooij, H. (author), Van Asseldonk, Edwin H.F. (author)People with spasticity, i.e., stretch hyperreflexia, have a limited functional independence and mobility. While a broad range of spasticity treatments is available, many treatments are invasive, non-specific, or temporary and might have negative side effects. Operant conditioning of the stretch reflex is a promising non-invasive paradigm with...journal article 2021
- document
-
Sharifi, S. (author), Luft, F. (author), Potgieter, S. (author), Heida, T. (author), Mugge, W. (author), Schouten, A.C. (author), Bour, L. J. (author), van Rootselaar, A. F. (author)Objective: A role of the motor cortex in tremor generation in essential tremor (ET) is assumed, yet the directionality of corticomuscular coupling is unknown. Our aim is to clarify the role of the motor cortex. To this end we also study ‘familial cortical myoclonic tremor with epilepsy’ (FCMTE) and slow repetitive voluntary movements with a...journal article 2021
- document
-
van den Berg, Boudewijn (author), Manoochehri, M. (author), Kasting, Mindy (author), Schouten, A.C. (author), van der Helm, F.C.T. (author), Buitenweg, Jan R. (author)A sustained sensory stimulus with a periodic variation of intensity creates an electrophysiological brain response at associated frequencies, referred to as the steady-state evoked potential (SSEP). The SSEPs elicited by the periodic stimulation of nociceptors in the skin may represent activity of a brain network that is primarily involved in...journal article 2021
- document
-
Waasdorp, R. (author), Mugge, W. (author), Vos, H.J. (author), De Groot, Jurriaan H. (author), Verweij, M.D. (author), de Jong, N. (author), Schouten, A.C. (author), Daeichin, V. (author)Skeletal muscles generate force, enabling movement through a series of fast electro-mechanical activations coordinated by the central nervous system. Understanding the underlying mechanism of such fast muscle dynamics is essential in neuromuscular diagnostics, rehabilitation medicine and sports biomechanics. The unique combination of...journal article 2021
- document
-
van ’t Veld, Ronald C. (author), Schouten, A.C. (author), van der Kooij, H. (author), van Asseldonk, Edwin H.F. (author)Background: People with brain or neural injuries, such as cerebral palsy or spinal cord injury, commonly have joint hyper-resistance. Diagnosis and treatment of joint hyper-resistance is challenging due to a mix of tonic and phasic contributions. The parallel-cascade (PC) system identification technique offers a potential solution to...journal article 2021
- document
-
Piastra, Maria Carla (author), van der Cruijsen, J. (author), Piai, Vitória (author), Jeukens, Floor E.M. (author), Manoochehri, M. (author), Schouten, A.C. (author), Selles, R.W. (author), Oostendorp, Thom (author)Objective. Large structural brain changes, such as chronic stroke lesions, alter the current pathways throughout the patients' head and therefore have to be taken into account when performing transcranial direct current stimulation simulations. Approach. We implement, test and distribute the first MATLAB pipeline that automatically generates...journal article 2021
- document
-
Geelen, J.E. (author), Branco, Mariana P. (author), Ramsey, Nick F. (author), van der Helm, F.C.T. (author), Mugge, W. (author), Schouten, A.C. (author)Motion capture systems are extensively used to track human movement to study healthy and pathological movements, allowing for objective diagnosis and effective therapy of conditions that affect our motor system. Current motion capture systems typically require marker placements which is cumbersome and can lead to contrived movements.Here, we...conference paper 2021