Searched for: author%3A%22Van+Beusekom%2C+Heleen%22
(1 - 12 of 12)
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Slijkhuis, Nuria (author), Razzi, F. (author), Korteland, Suze Anne (author), Heijs, Bram (author), van Gaalen, Kim (author), Duncker, Dirk J. (author), van der Steen, A.F.W. (author), van Steijn, V. (author), van Beusekom, Heleen M.M. (author), van Soest, G. (author)
Coronary atherosclerosis is caused by plaque build-up, with lipids playing a pivotal role in its progression. However, lipid composition and distribution within coronary atherosclerosis remain unknown. This study aims to characterize lipids and investigate differences in lipid composition across disease stages to aid in the understanding of...
journal article 2024
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Cahalane, Rachel M.E. (author), Cruts, Janneke M.H. (author), van Beusekom, Heleen M.M. (author), de Maat, Moniek P.M. (author), Dijkshoorn, Marcel (author), van der Lugt, Aad (author), Gijsen, F.J.H. (author)
Thrombus computed tomography (CT) imaging characteristics may correspond with thrombus mechanical properties and thus predict thrombectomy success. The impact of red blood cell (RBC) content on these properties (imaging and mechanics) has been widely studied. However, the additional effect of platelets has not been considered. The objective...
journal article 2024
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Su, Ruisheng (author), van der Sluijs, P. Matthijs (author), Bobi, Joaquim (author), Taha, Aladdin (author), van Beusekom, Heleen M.M. (author), van der Lugt, Aad (author), Niessen, W.J. (author), Ruijters, Danny (author), van Walsum, T. (author)
Background: X-ray digital subtraction angiography (DSA) is the imaging modality for peri-procedural guidance and treatment evaluation in (neuro-) vascular interventions. Perfusion image construction from DSA, as a means of quantitatively depicting cerebral hemodynamics, has been shown feasible. However, the quantitative property of perfusion...
journal article 2023
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Cahalane, R.M.E. (author), de Vries, J.J. (author), de Maat, Moniek P.M. (author), van Gaalen, Kim (author), van Beusekom, Heleen M. (author), van der Lugt, Aad (author), Fereidoonnezhad, B.F. (author), Akyildiz, A.C. (author), Gijsen, F.J.H. (author)
Endovascular thrombectomy procedures are significantly influenced by the mechanical response of thrombi to the multi-axial loading imposed during retrieval. Compression tests are commonly used to determine compressive ex vivo thrombus and clot analogue stiffness. However, there is a shortage of data in tension. This study compares the tensile...
journal article 2023
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Deen, Aaron Doug (author), van Beusekom, Heleen M.M. (author), Pfeiffer, Tom (author), Stam, Mathijs (author), Kleijn, Dominique D.E. (author), Wentzel, Jolanda (author), Huber, Robert (author), van der Steen, A.F.W. (author), Van Soest, Gijs (author), Wang, Tianshi (author)
Optical imaging techniques that provide free space, label free imaging are powerful tools in obtaining structural and biochemical information in biological samples. To date, most of the optical imaging technologies create images with a specific contrast and require multimodality integration to add additional contrast. In this study, we...
journal article 2022
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Wang, Tianshi (author), Pfeiffer, Tom (author), Akyildiz, A.C. (author), van Beusekom, Heleen M.M. (author), Huber, Robert (author), van der Steen, A.F.W. (author), Soest, Gijs Van (author)
Optical coherence elastography (OCE), a functional extension of optical coherence tomography (OCT), visualizes tissue strain to deduce the tissue’s biomechanical properties. In this study, we demonstrate intravascular OCE using a 1.1 mm motorized catheter and a 1.6 MHz Fourier domain mode-locked OCT system. We induced an intraluminal pressure...
journal article 2022
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Razzi, F. (author), Lovrak, M. (author), Gruzdyte, Dovile (author), Den Hartog, Yvette (author), Duncker, Dirk J. (author), van Esch, J.H. (author), van Steijn, V. (author), van Beusekom, Heleen M.M. (author)
Atherosclerotic arteries are commonly treated using drug-eluting stents (DES). However, it remains unclear whether and how the properties of atherosclerotic plaque affect drug transport in the arterial wall. A limitation of the currently used atherosclerotic animal models to study arterial drug distribution is the unpredictability of plaque...
journal article 2021
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Doug Deen, Aaron (author), Pfeiffer, Tom (author), Van Beusekom, Heleen (author), Essers, J. (author), Huber, Robert (author), van der Steen, A.F.W. (author), Van Soest, Gijs (author), Wang, Tianshi (author)
The absorption of laser pulses by tissue leads not only to the generation of acoustic waves, but also to nanometer to sub-micrometer scale displacement. After the initial expansion, a quasi-steady state is achieved in a few microseconds. Previously we introduced the concept of thermo-elastic optical coherence tomography (TE-OCT) to "visualise...
conference paper 2020
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Cecchetti, Leonardo (author), Wang, Tianshi (author), Hoogendoorn, Ayla (author), Witberg, Karen T. (author), Ligthart, Jurgen M.R. (author), Daemen, Joost (author), van Beusekom, Heleen M.M. (author), Pfeiffer, Tom (author), van der Steen, A.F.W. (author)
To quantify the impact of cardiac motion on stent length measurements with Optical Coherence Tomography (OCT) and to demonstrate in vivo OCT imaging of implanted stents, without motion artefacts. The study consists of: clinical data evaluation, simulations and in vivo tests. A comparison between OCT-measured and nominal stent lengths in 101...
journal article 2020
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López-Marín, Antonio (author), Springeling, Geert (author), Beurskens, Robert (author), Van Beusekom, Heleen (author), van der Steen, A.F.W. (author), Koch, Arjun D. (author), Bouma, Brett E. (author), Huber, Robert A. (author), Van Soest, Gijs (author), Wang, Tianshi (author)
In this study, we demonstrate a 12x36 mm motorized capsule for OCT imaging of the esophagus. The capsule produces unobstructed images by using a distal reflector design, thus avoiding shadow caused by the motor wires. The motor synchronous control enables three working modes: circumferential imaging, angular sector imaging and accurate beam...
conference paper 2020
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López-Marín, Antonio (author), Springeling, Geert (author), Beurskens, Robert (author), van Beusekom, Heleen (author), van der Steen, A.F.W. (author), Koch, Arjun D. (author), Bouma, Brett E. (author), Huber, Robert (author), Soest, Gijs V.A.N. (author), Wang, Tianshi (author)
We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam...
journal article 2019
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Wu, Min (author), Springeling, Geert (author), Lovrak, M. (author), Mastik, Frits (author), Iskander-Rizk, Sophinese (author), Wang, Tianshi (author), Van Beusekom, Heleen M.M. (author), van der Steen, A.F.W. (author), van Soest, G. (author)
Lipid deposition can be assessed with combined intravascular photoacoustic/ultrasound (IVPA/US) imaging. To date, the clinical translation of IVPA/US imaging has been stalled by a low imaging speed and catheter complexity. In this paper, we demonstrate imaging of lipid targets in swine coronary arteries in vivo, at a clinically useful frame...
journal article 2017
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