Searched for: author%3A%22Verhaegen%2C+M.H.G.%22
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Piscaer, P.J. (author), Soloviev, O.A. (author), Verhaegen, M.H.G. (author)
This paper discusses various practical problems arising in the design and simulation of predictive control methods for adaptive optics. Although there has been increased attention towards optimal prediction and control methods for AO systems, they are often tested in simplified simulation environments. The use of advanced AO simulators...
conference paper 2020
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Soloviev, O.A. (author), Verhaegen, M.H.G. (author), Vdovin, Gleb (author)
Shack-Hartmann (SH) sensor, based on sampling of wavefront tilts in subapertures, is a simple, reliable, and widely used in adaptive optics wavefront sensor. A wavefront curvature sensor has the advantage of providing the results suitable for direct control of membrane and bimorph deformable mirrors [1], but requires linear registration of...
conference paper 2015
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Gong, H. (author), Pozzi, P. (author), Soloviev, O.A. (author), Verhaegen, M.H.G. (author), Vdovin, Gleb (author)
We investigate the possibility of interferometric optical field sensor with DMD forming a series of sampling interferometers in the pupil of an optical system. Our preliminary experiment validates the feasibility of our approach for the field reconstruction in the case of coherent field. We believe that this approach can be extended to sensing...
conference paper 2015
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Gong, H. (author), Pozzi, P. (author), Soloviev, O.A. (author), Verhaegen, M.H.G. (author), Vdovin, Gleb (author)
We present a reference-less and time-multiplexing phase retrieval method by making use of the digital micromirror device (DMD). In this method, the DMD functions not only as a flexible binary mask which modulates the optical field, but also as a sampling mask for measuring corresponding phases, which makes the whole setup simple and robust. The...
conference paper 2016
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Noom, J. (author), Soloviev, O.A. (author), Smith, C.S. (author), Nguyen, Hieu Thao (author), Verhaegen, M.H.G. (author)
We demonstrate a novel closed-loop input design technique on the detection of particles in an imaging system such as a fluorescence microscope. The probability of misdiagnosis is minimized while constraining the input energy such that for instance phototoxicity is reduced. The key novelty of the closed-loop design is that each next input is...
conference paper 2022
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Noom, J. (author), Soloviev, O.A. (author), Smith, C.S. (author), Verhaegen, M.H.G. (author)
Some applications require high level of image-based classification certainty while keeping the total illumination energy as low as possible. Examples are minimally invasive visual inspection in Industry 4.0, and medical imaging systems such as computed tomography, in which the radiation dose should be kept “as low as is reasonably achievable”...
conference paper 2022
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Wilding, D. (author), Pozzi, P. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)
Aberrations, scattering and absorption degrade the performance light-sheet fluorescence microscopes (LSFM). An adaptive optics system to correct for these artefacts and to optimize the light-sheet illumination is presented. This system allows a higher axial resolution to be recovered over the field-of-view of the detection objective. It is...
conference paper 2016
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Agbana, T.E. (author), Yang, H. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)
This paper presents experimental results of a static aberration control algorithm based on the linear relation be- tween mean square of the aberration gradient and the second moment of point spread function for the generation of control signal input for a deformable mirror (DM). Results presented in the work of Yang et al.1 suggested a good...
conference paper 2016
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Pozzi, P. (author), Wilding, D. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)
This proceeding reports early results in the development of a new technique for adaptive optics in confocal microscopy. The term adaptive optics refers to the branch of optics in which an active element in the optical system is used to correct inhomogeneities in the media through which light propagates. In its most classical form, mostly used in...
conference paper 2016
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Soloviev, O.A. (author), Noom, J. (author), Nguyen, Hieu Thao (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)
We investigate the general adjustment of projection-based phase retrieval algorithms for use with saturated data. In the phase retrieval problem, model fidelity of experimental data containing a non-zero background level, fixed pattern noise, or overexposure, often presents a serious obstacle for standard algorithms. Recently, it was shown...
conference paper 2022
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Wilding, D. (author), de Iongh, Gijs (author), Soloviev, O.A. (author), Pozzi, P. (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)
By taking multiple input-output measurements, it is shown how to determine the input to an optical system that corrects unknown phase aberrations without interferometric measurements or online iterative optimization within a couple of seconds. It is shown to work in simulations and experiment. This technique may also be used to acquire the...
conference paper 2017
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Wilding, D. (author), Pozzi, P. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)
In life sciences, interest in the microscopic imaging of increasingly complex three dimensional samples, such as cell spheroids, zebrafish embryos, and in vivo applications in small animals, is growing quickly. Due to the increasing complexity of samples, more and more life scientists are considering the implementation of adaptive optics in...
conference paper 2018
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Pozzi, P. (author), Wilding, D. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Verhaegen, M.H.G. (author)
In this work, we present a new confocal laser scanning microscope capable to perform sensorless wavefront optimization in real time. The device is a parallelized laser scanning microscope in which the excitation light is structured in a lattice of spots by a spatial light modulator, while a deformable mirror provides aberration correction and...
conference paper 2018
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Wilding, D. (author), Pozzi, P. (author), Soloviev, O.A. (author), Vdovin, Gleb (author), Fiolka, Reto (author), Verhaegen, M.H.G. (author)
The light-sheet fluorescence microscopy is an excellent tool for the investigation of large three dimensional microscopy samples at the cellular level, however, the ability to resolve features is strongly affected by the presence of scattering and aberrations. These effects are two fold in light-sheet microscopy, as the illumination path...
conference paper 2018
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Noom, J. (author), Nguyen, Hieu Thao (author), Soloviev, O.A. (author), Verhaegen, M.H.G. (author)
This manuscript presents an improvement of state-of-the-art Closed-Loop Active Model Diagnosis (CLAMD). The proposed method utilizes weighted Bhattacharyya coefficients evaluated at the vertices of the polytopic constraint set to provide a good trade-off between computational efficiency and satisfactory input choice for separation of candidate...
conference paper 2021
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Hung, S. (author), Llobet Rosell, Arnau (author), Jurriens, Daphne (author), Soloviev, O.A. (author), Kapitein, Lukas C. (author), Grußmayer, K.S. (author), Neukomm, Lukas J. (author), Verhaegen, M.H.G. (author), Smith, C.S. (author)
Single-molecule localization microscopy (SMLM) enables the high-resolution visualization of organelle structures and the precise localization of individual proteins. However, the expected resolution is not achieved in tissue as the imaging conditions deteriorate. Sample-induced aberrations distort the point spread function (PSF), and high...
journal article 2022
document
Piscaer, P.J. (author), Soloviev, O.A. (author), Verhaegen, M.H.G. (author)
This paper presents a computationally efficient framework in which a single focal-plane image is used to obtain a high-resolution reconstruction of dynamic aberrations. Assuming small-phase aberrations, a non-linear Kalman filter implementation is developed whose computational complexity scales close to linearly with the number of pixels of...
journal article 2021
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Nguyen, Hieu Thao (author), Soloviev, O.A. (author), Luke, Russell (author), Verhaegen, M.H.G. (author)
We develop for the first time a mathematical framework in which the class of projection algorithms can be applied to high numerical aperture (NA) phase retrieval. Within this framework, we first analyze the basic steps of solving the high-NA phase retrieval problem by projection algorithms and establish the closed forms of all the relevant...
journal article 2021
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Nguyen, Hieu Thao (author), Soloviev, O.A. (author), Verhaegen, M.H.G. (author)
We present the convergence analysis of convex combination of the alternating projection and Douglas–Rachford operators for solving the phase retrieval problem. New convergence criteria for iterations generated by the algorithm are established by applying various schemes of numerical analysis and exploring both physical and mathematical...
journal article 2021
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Vdovin, Gleb (author), Gong, H. (author), Soloviev, O.A. (author), Pozzi, P. (author), Verhaegen, M.H.G. (author)
We have experimentally demonstrated a lensless coherent microscope based on direct registration of the complex optical field by sampling the pupil with a sequence of two-point interferometers formed by a digital micromirror device. Complete registration of the complex amplitude in the pupil of the imaging system, without any reference beam,...
journal article 2015
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