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Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol

Zhao, Z. (author), Kuijvenhoven, K. (author), Van Gulik, W.M. (author), Heijnen, J.J. (author), Van Winden, W.A. (author), Verheijen, P.J.T. (author)

The in vivo flux through the oxidative branch of the pentose phosphate pathway (oxPPP) in Penicillium chrysogenum was determined during growth in glucose/ethanol carbon-limited chemostat cultures, at the same growth rate. Non-stationary 13C flux analysis was used to measure the oxPPP flux. A nearly constant oxPPP flux was found for all glucose...

journal article 2010

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Metabolite and reaction inference based on enzyme specificities

De Groot, M.J.L. (author), Van Berlo, R.J.P. (author), Van Winden, W.A. (author), Verheijen, P.J.T. (author), Reinders, M.J.T. (author), De Ridder, D. (author)

Motivation: Many enzymes are not absolutely specific, or even promiscuous: they can catalyze transformations of more compounds than the traditional ones as listed in e.g. KEGG. This information is currently only available in databases, such as the BRENDA enzyme activity database. In this paper, we propose to model enzyme aspecificity by...

journal article 2009

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Optimization studies in sulfuric acid production

Kiss, A.A. (author), Bildea, C.S. (author), Verheijen, P.J.T. (author)

journal article 2006

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Modelling and optimisation of industrial absorption processes: An EC collaborative research project

Seferlis, P. (author), Dalaouti, N. (author), Kenig, E.Y. (author), Huepen, B. (author), Patil, P. (author), Jobson, M. (author), Klemes, J. (author), Proios, P. (author), Georgiadis, M.C. (author), Pistikopoulos, E.N. (author), Singare, S. (author), Bildea, C.S. (author), Grievink, J. (author), Verheijen, P.J.T. (author), Hostrup, M. (author), Harper, P. (author), Vlachopoulos, G. (author), Kerasidis, C. (author), Katsanevakish, J. (author), Constantinidis, D. (author), Stehlik, P. (author), Fernholz, G. (author)

journal article 2005

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The quest for intensified steam cracking process

Van Goethem, M.W.M. (author), Verheijen, P.J.T. (author)

In this paper the results are presented on the quest for an intensified steam cracking process. The main focus is to improve the efficiency of the steam cracking process. The first part of the investigation is to examine which of the current available processes is close to the ideal steam cracking process. Two possible technologies have...

conference paper 2005

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Improved characterization of small particles in laser diffraction by better optical modeling

Butselaar, V.C.L. (author), Schouten, L.A. (author), Verheijen, P.J.T. (author)

Laser Diffraction is widely used for the characterization of particle size distributions of powders. For a lot of materials however, the quantification of small particles (< 2 ?m) in relation to the rest of the distribution can be ambiguous. The deconvolution of the scattering pattern is done either with the Fraunhofer approximation or the Mie...

conference paper 2004

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Efficient modeling of 13C-labeling distributions in microorganisms

Van Winden, W.A. (author), Verheijen, P.J.T. (author), Heijnen, J.J. (author)

journal article 2003

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Model selection: An overview of practices in chemical engineering

Verheijen, P.J.T. (author)

journal article 2003

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Synthesis of large-scale models: Theory and implementation in an industrial case

Schmal, J.P. (author), Grievink, J. (author), Verheijen, P.J.T. (author)

journal article 2002

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Modeling and optimization of a sugar plant using hybrid: Batch model predictive control

Van Wissen, M.E. (author), Smeets, J.F.C. (author), Muller, A. (author), Verheijen, P.J.T. (author)

journal article 2002

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A post-graduate study in process design: An innovative model in the Netherlands

Grievink, J. (author), Bierman, G. (author), Luteijn, C.P. (author), Verheijen, P.J.T. (author)

journal article 2002

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Increasing the selectivity of the Fischer Tropsch process by periodic operation

Meeuse, F.M. (author), De Deugd, R.M. (author), Kapteijn, F. (author), Verheijen, P.J.T. (author), Ypma, S.M. (author)

journal article 2001

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A design procedure and predictive models for solution crystallisation processes

Bermingham, S.K. (author), Neumann, A.M. (author), Kramer, H.J.M. (author), Verheijen, P.J.T. (author), Van Rosmalen, G.M. (author), Grievink, J. (author)

journal article 2000

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Monitoring heat exchanger fouling for optimal operation of a multiple effect evaporator

Bermingham, S.K. (author), Jonkers, M. (author), Kruizinga, G.J. (author), Van Reisen, J.L.B. (author), Verheijen, P.J.T. (author)

journal article 1999

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Conceptual design of processes for structured products

Meeuse, F.M. (author), Grievink, J. (author), Verheijen, P.J.T. (author), Vander Stappen, M.L.M. (author)

journal article 1999

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On the performance of an on-line time-of-flight mass spectrometer for aerosols

Weiss, M. (author), Verheijen, P.J.T. (author), Marijnissen, J.C.M. (author), Scarlett, B. (author)

journal article 1997

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Implementation of novel processes in existing process networks: Evaluation of the industrial production of C4 chemicals by optimization

Dijkema, G.P.J. (author), Steenkamp, E.M. (author), Verheijen, P.J.T. (author)

journal article 1997

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Influence of noise on power-law scaling functions and an algorithm for dimension estimations

Oltmans, H. (author), Verheijen, P.J.T. (author)

journal article 1997

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Dust explosions in spherical vessels: Prediction of the pressure evolution and determination of the burning velocity and flame thickness

Dahoe, A.E. (author), Zevenbergen, J.F. (author), Verheijen, P.J.T. (author), Lemkowitz, S.M. (author), Scarlett, B. (author)

A well known limitation of the ’cube-root-law’ is that it becomes invalid when the flame thickness is significant with respect to the vessel radius. In the literature flame thicknesses in dust-air mixtures ranging from 15 to 80 centimeters have been reported [1], which exceed the radii of the 20-1itre sphere and the 1 m3 vessel. Therefore we...

journal article 1996

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Correction of the effect of particle shape on the size distribution measured with a laser diffraction instrument

Heffels, C.M.G. (author), Verheijen, P.J.T. (author), Heitzmann, D. (author), Scarlett, B. (author)

journal article 1996