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Beekers, D.I. (author), Vegter, Merel (author), Lattwein, Kirby R. (author), Mastik, Frits (author), Beurskens, Robert (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)Ultrasound insonification of microbubbles can locally increase vascular permeability to enhance drug delivery. To control and optimize the therapeutic potential, we need to better understand the underlying biological mechanisms of the drug delivery pathways. The aim of this in vitro study was to elucidate the microbubble-endothelial cell...journal article 2020
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Beekers, D.I. (author), Mastik, Frits (author), Beurskens, Robert (author), Tang, Phoei Ying (author), Vegter, Merel (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)Ultrasound insonification of microbubbles can locally enhance drug delivery, but the microbubble–cell interaction remains poorly understood. Because intracellular calcium (Ca<sub>i</sub> <sup>2+</sup>) is a key cellular regulator, unraveling the Ca<sub>i</sub> <sup>2+</sup> fluctuations caused by an oscillating microbubble provides crucial...journal article 2020
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Janjic, Jovana (author), Tan, M. (author), Daeichin, V. (author), Noothout, E.C. (author), Chen, C. (author), Chen, Z. (author), Chang, Z.Y. (author), Beurskens, Robert H.S.H. (author), van Soest, G. (author), van der Steen, A.F.W. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author), de Jong, N. (author)Intravascular ultrasound is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking intravascular ultrasound (FL-IVUS), instead of the conventional side-looking geometry. Volumetric imaging can be achieved with 2D array...journal article 2018