Searched for: author:"de Jong, N."
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Saaid, Hicham (author), Voorneveld, Jason D. (author), Schinkel, C.V. (author), Westenberg, Jos J.M. (author), Gijsen, F.J.H. (author), Segers, Patrick (author), Verdonck, Pascal (author), de Jong, N. (author), Kenjeres, S. (author), More Authors (author)
Left ventricular flow is intrinsically complex, three-dimensional and unsteady. Its features are susceptible to cardiovascular pathology and treatment, in particular to surgical interventions involving the valves (mitral valve replacement). To improve our understanding of intraventricular fluid mechanics and the impact of various types of...
journal article 2019
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Ruf, M.T. (author), IJspeert, M. (author), van Dam, S.B. (author), de Jong, N. (author), van den Berg, J.H. (author), Hanson, R. (author)
Diamond membrane devices containing optically coherent nitrogen-vacancy (NV) centers are key to enable novel cryogenic experiments such as optical ground-state cooling of hybrid spin-mechanical systems and efficient entanglement distribution in quantum networks. Here, we report on the fabrication of a (3.4 ± 0.2) μm thin, smooth (surface...
journal article 2019
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Beekers, D.I. (author), Lattwein, Kirby R. (author), Kouijzer, Joop J.P. (author), Langeveld, Simone A.G. (author), Vegter, M. (author), Beurskens, Robert (author), Mastik, Frits (author), Verduyn Lunel, Rogier (author), van der Steen, A.F.W. (author), de Jong, N. (author)
Controlling microbubble-mediated drug delivery requires the underlying biological and physical mechanisms to be unraveled. To image both microbubble oscillation upon ultrasound insonification and the resulting cellular response, we developed an optical imaging system that can achieve the necessary nanosecond temporal and nanometer spatial...
journal article 2019
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Mozaffarzadeh, M. (author), Haji Heidari Varnosfaderani, Mehdi (author), Sharma, Arunima (author), Pramanik, Manojit (author), de Jong, N. (author), Verweij, M.D. (author)
In acoustic-resolution photoacoustic microscopy (AR-PAM) systems, the lateral resolution in the focal zone of the ultrasound (US) transducer is determined by the numerical aperture (NA) of the transducer. To have a high lateral resolution, a large NA is used. However, the larger the NA, the smaller the depth of focus [DOF]. As a result, the...
journal article 2019
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Voorneveld, J.D. (author), Engelhard, S. (author), Vos, H.J. (author), Reijnen, M. (author), Gijsen, F.J.H. (author), Versluis, M. (author), Jebbink, Erik Groot (author), de Jong, N. (author), Bosch, J. G. (author)
Treatment of abdominal aortic (AA) aneurysms and stenotic lesions may be improved by analyzing their associated blood flow patterns. Angle-independent blood flow patterns in the AA can be obtained by combining echo-particle image velocimetry (ePIV) with high frame rate contrast-enhanced ultrasonography. However, ePIV performance is affected...
journal article 2018
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Lajoinie, Guillaume (author), Luan, Ying (author), Gelderblom, Erik (author), Dollet, Benjamin (author), Mastik, Frits (author), Dewitte, Heleen (author), Lentacker, Ine (author), de Jong, N. (author), Versluis, Michel (author)
journal article 2018
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Beekers, D.I. (author), van Rooij, Tom (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)
Ultrasound contrast agents consist of gas-filled coated microbubbles that oscillate upon ultrasound insonification. Their characteristic oscillatory response provides contrast enhancement for imaging and has the potential to locally enhance drug delivery. Since microbubble response depends on the local acoustic pressure, an ultrasound...
journal article 2018
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Janjic, Jovana (author), Tan, M. (author), Daeichin, V. (author), Noothout, E.C. (author), Chen, C. (author), Chen, Z. (author), Chang, Z.Y. (author), Beurskens, Robert H.S.H. (author), van Soest, G. (author), van der Steen, A.F.W. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author), de Jong, N. (author)
Intravascular ultrasound is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking intravascular ultrasound (FL-IVUS), instead of the conventional side-looking geometry. Volumetric imaging can be achieved with 2D array...
journal article 2018
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Skachkov, Ilya (author), Luan, Ying (author), Van Tiel, Sandra T. (author), van der Steen, A.F.W. (author), de Jong, N. (author), Bernsen, Monique R. (author), Kooiman, Klazina (author)
In vivo cell tracking of therapeutic, tumor, and endothelial cells is an emerging field and a promising technique for imaging cardiovascular disease and cancer development. Site-specific labeling of endothelial cells with the MRI contrast agent superparamagnetic iron oxide (SPIO) in the absence of toxic agents is challenging. Therefore, the...
journal article 2018
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Chen, C. (author), Chen, Z. (author), Bera, Deep (author), Noothout, E.C. (author), Chang, Z.Y. (author), Tan, M. (author), Vos, H.J. (author), Bosch, Johan G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)
This paper presents a front-end application-specified integrated circuit (ASIC) integrated with a 2-D PZT matrix transducer that enables in-probe digitization with acceptable power dissipation for the next-generation endoscopic and catheter-based 3-D ultrasound imaging systems. To achieve power-efficient massively parallel analog-to-digital...
journal article 2018
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Massaad Mouawad, J.M. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), de Jong, N. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author)
Typically, ultrasonic flow meters assume linear wave propagation. Nevertheless, if the transducers of an ultrasonic flow sensor excite a pressure wave with a high amplitude, nonlinear wave propagation effects become significant. The appearance of higher harmonics increases the bandwidth of the received signal, which may potentially lead to a...
conference paper 2018
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Daeichin, V. (author), Bera, D. (author), Raghunathan, S.B. (author), Shabanimotlagh, M. (author), Chen, Z. (author), Chen, C. (author), Noothout, E.C. (author), Vos, H.J. (author), Pertijs, M.A.P. (author), de Jong, N. (author), Verweij, M.D. (author), More Authors (author)
This paper presents the design, fabrication and characterization of a miniature PZT-on-CMOS matrix transducer for real-time pediatric 3-dimensional (3D) transesophageal echocardiography (TEE). This 3D TEE probe consists of a 32 × 32 array of PZT elements integrated on top of an Application Specific Integrated Circuit (ASIC). We propose a...
journal article 2018
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Bera, D. (author), Van Den Adel, Franc (author), Radeljic-Jakic, Nikola (author), Lippe, Boris (author), Soozande, M. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), Kruizinga, P. (author), Daeichin, V. (author), Vos, H.J. (author), van der Steen, A.F.W. (author), Bosch, Johan G. (author), de Jong, N. (author)
We describe a 3-D multiline parallel beamforming scheme for real-time volumetric ultrasound imaging using a prototype matrix transesophageal echocardiography probe with diagonally diced elements and separated transmit and receive arrays. The elements in the smaller rectangular transmit array are directly wired to the ultrasound system. The...
journal article 2018
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Fool, F. (author), de Wit, J. (author), Vos, H.J. (author), Bera, D. (author), de Jong, N. (author), Verweij, M.D. (author)
The huge amount of data that needs to be transferred between probe and imaging system becomes a major issue when the data transfer capacity is limited, e.g. in handheld systems, wireless probes and miniaturized probes. The amount of data can be significantly reduced by using two-stage beamforming. The first stage consists of a fixed focus...
conference paper 2018
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Tan, M. (author), Chen, C. (author), Chen, Z. (author), Janjic, Jovana (author), Daeichin, V. (author), Chang, Z.Y. (author), Noothout, E.C. (author), van Soest, G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)
This paper presents an area- and power-efficient application-specified integrated circuit (ASIC) for 3-D forward-looking intravascular ultrasound imaging. The ASIC is intended to be mounted at the tip of a catheter, and has a circular active area with a diameter of 1.5 mm on the top of which a 2-D array of piezoelectric transducer elements is...
journal article 2018
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Kang, E. (author), Ding, Q. (author), Shabanimotlagh, M. (author), Kruizinga, P. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, J.W. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)
This paper presents an ultrasound transceiver application-specific integrated circuit (ASIC) designed for 3-D ultrasonic imaging of the carotid artery. This application calls for an array of thousands of ultrasonic transducer elements, far exceeding the number of channels of conventional imaging systems. The 3.6 x 6.8 mm² ASIC...
journal article 2018
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Bera, D. (author), Raghunathan, S.B. (author), Chen, C. (author), Chen, Z. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), Daeichin, V. (author), Vos, H.J. (author), van der Steen, A.F.W. (author), de Jong, N. (author), Bosch, J.G. (author)
Until now, no matrix transducer has been realized for 3D transesophageal echocardiography (TEE) in pediatric patients. In 3D TEE with a matrix transducer, the biggest challenges are to connect a large number of elements to a standard ultrasound system, and to achieve a high volume rate (>200 Hz). To address these issues, we have recently...
journal article 2018
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Kruizinga, P. (author), van der Meulen, P.F. (author), Fedjajevs, A. (author), Mastik, F (author), Springeling, Geert (author), de Jong, N. (author), Bosch, J.G. (author), Leus, G.J.T. (author)
Three-dimensional ultrasound is a powerful imaging technique, but it requires thousands of sensors and complex hardware. Very recently, the discovery of compressive sensing has shown that the signal structure can be exploited to reduce the burden posed by traditional sensing requirements. In this spirit, we have designed a simple ultrasound...
journal article 2017
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Strachinaru, Mihai (author), Bosch, Johan G. (author), van Dalen, Bas M. (author), van Gils, Lennart (author), van der Steen, A.F.W. (author), de Jong, N. (author), Geleijnse, Marcel L. (author), Vos, H.J. (author)
The propagation velocity of shear waves relates to tissue stiffness. We prove that a regular clinical cardiac ultrasound system can determine shear wave velocity with a conventional unmodified tissue Doppler imaging (TDI) application. The investigation was performed on five tissue phantoms with different stiffness using a research platform...
journal article 2017
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Kokhuis, Tom J A (author), Naaijkens, Benno A. (author), Juffermans, Lynda J.M. (author), Kamp, Otto (author), van der Steen, A.F.W. (author), Versluis, Michel (author), de Jong, N. (author)
The use of stem cells for regenerative tissue repair is promising but hampered by the low number of cells delivered to the site of injury. To increase the delivery, we propose a technique in which stem cells are linked to functionalized microbubbles, creating echogenic complex dubbed StemBells. StemBells are highly susceptible to acoustic...
journal article 2017
Searched for: author:"de Jong, N."
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