Searched for: author%3A%22de+Jong%2C+S.I.%22
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de Jong, S.I. (author)
Alkaliphiles thrive in environments with a pH of 8.5 or above, while maintaining an internal pH closer to neutral. Thus, alkaliphilic microorganisms have a proton gradient inverted with respect to the normal orientation. Intuitively, this would nullify the potential to generate energy via respiration with regularly oriented respiratory chains...
doctoral thesis 2024
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Krah, Alexander (author), Vogelaar, Timothy (author), de Jong, S.I. (author), Claridge, Jolyon K. (author), Bond, Peter J. (author), McMillan, D.G.G. (author)
It is a conjecture that the ε subunit regulates ATP hydrolytic function of the F1Fo ATP synthase in bacteria. This has been proposed by the ε subunit taking an extended conformation, with a terminal helix probing into the central architecture of the hexameric catalytic domain, preventing ATP hydrolysis. The ε subunit takes a contracted...
journal article 2023
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de Jong, S.I. (author), Sorokin, Dimitry Y. (author), van Loosdrecht, Mark C.M. (author), Pabst, Martin (author), McMillan, D.G.G. (author)
Proteomics has greatly advanced the understanding of the cellular biochemistry of microorganisms. The thermoalkaliphile Caldalkalibacillus thermarum TA2.A1 is an organism of interest for studies into how alkaliphiles adapt to their extreme lifestyles, as it can grow from pH 7.5 to pH 11. Within most classes of microbes, the membrane-bound...
journal article 2023
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de Jong, S.I. (author), van den Broek, M.A. (author), Merkel, Alexander Y. (author), de la Torre Cortes, Pilar (author), Kalamorz, Falk (author), Cook, Gregory M. (author), van Loosdrecht, Mark C.M. (author), McMillan, D.G.G. (author)
The aerobic thermoalkaliphile Caldalkalibacillus thermarum strain TA2.A1 is a member of a separate order of alkaliphilic bacteria closely related to the Bacillales order. Efforts to relate the genomic information of this evolutionary ancient organism to environmental adaptation have been thwarted by the inability to construct a complete...
journal article 2020
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