- document
-
Zelle, R.M. (author), Harrison, J.C. (author), Pronk, J.T. (author), Van Maris, A.J.A. (author)Malic enzyme catalyzes the reversible oxidative decarboxylation of malate to pyruvate and CO2. The Saccharomyces cerevisiae MAE1 gene encodes a mitochondrial malic enzyme whose proposed physiological roles are related to the oxidative, malate-decarboxylating reaction. Hitherto, the inability of pyruvate carboxylase-negative (Pyc–) S. cerevisiae...journal article 2010
- document
-
Zelle, R.M. (author), Trueheart, J. (author), Harrison, J.C. (author), Pronk, J.T. (author), Van Maris, A.J.A. (author)Pyruvate carboxylase is the sole anaplerotic enzyme in glucose-grown cultures of wild-type Saccharomyces cerevisiae. Pyruvate carboxylase-negative (Pyc–) S. cerevisiae strains cannot grow on glucose unless media are supplemented with C4 compounds, such as aspartic acid. In several succinate-producing prokaryotes, phosphoenolpyruvate...journal article 2010