Tuneable Control of Organocatalytic Activity through Host–Guest Chemistry

Dynamic regulation of chemical reactivity is important in many complex chemical reaction networks, such as cascade reactions and signal transduction processes. Signal responsive catalysts could play a crucial role in regulating these reaction pathways. Recently, supramolecular encapsulation was reported to regulate the activities of...

A fuel-driven chemical reaction network based on conjugate addition and elimination chemistry

Fuel-driven chemical reaction networks provide an opportunity to develop chemical systems that operate out-ofequilibrium. There remains a need to design and develop new fueldriven chemical reaction networks capable of repeated operation using simple and benign chemistry. Here, we propose a new chemical reaction network for fuel-driven transient...

Catalytic control in out-of-equilibrium assembly systems

Nature is capable of constantly adapting some of its assembled structures in response to external and internal signals. For instance, microtubuli grow and shrink upon cell division and cellular transport. Furthermore, actin fibers play a major role in muscle contraction and cell signaling. To achieve these transient functions, such assembled...

Aniline Catalysed Hydrazone Formation Reactions Show a Large Variation in Reaction Rates and Catalytic Effects

Hydrazone formation reactions from aldehydes and hydrazides have the remarkable qualities that they proceed in water and the kinetics can be controlled by organocatalysis. For these reasons, this class of reactions finds widespread use in biological as well as material settings. We recently reported a protected aniline catalyst for hydrazone...