Searched for: author:"van Soest, G."
(1 - 13 of 13)
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Janjic, Jovana (author), Tan, M. (author), Daeichin, V. (author), Noothout, E.C. (author), Chen, C. (author), Chen, Z. (author), Chang, Z.Y. (author), Beurskens, Robert H.S.H. (author), van Soest, G. (author), van der Steen, A.F.W. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author), de Jong, N. (author)
Intravascular ultrasound is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking intravascular ultrasound (FL-IVUS), instead of the conventional side-looking geometry. Volumetric imaging can be achieved with 2D array...
journal article 2018
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Iskander-Rizk, Sophinese (author), Kruizinga, P. (author), Van Der Steen, Antonius F.W. (author), van Soest, G. (author), van der Steen, A.F.W. (author)
Catheter-based radiofrequency ablation for atrial fibrillation has long-term success in 60-70% of cases. A better assessment of lesion quality, depth, and continuity could improve the procedure’s outcome. We investigate here photoacoustic contrast between ablated and healthy atrial-wall tissue in vitro in wavelengths spanning from 410 nm to...
journal article 2018
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Janjic, Jovana (author), Kruizinga, P. (author), van der Meulen, P.Q. (author), Springeling, Geert (author), Mastik, Frits (author), Leus, G.J.T. (author), Bosch, Johan G. (author), van der Steen, A.F.W. (author), van Soest, G. (author)
We present a form of acoustic microscopy, called Structured Ultrasound Microscopy (SUM). It creates a volumetric image by recording reflected echoes of ultrasound waves with a structured phase front using a moving single-element transducer and computational reconstruction. A priori knowledge of the acoustic field produced by the single...
journal article 2018
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Tan, M. (author), Chen, C. (author), Chen, Z. (author), Janjic, Jovana (author), Daeichin, V. (author), Chang, Z.Y. (author), Noothout, E.C. (author), van Soest, G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)
This paper presents an area- and power-efficient application-specified integrated circuit (ASIC) for 3-D forward-looking intravascular ultrasound imaging. The ASIC is intended to be mounted at the tip of a catheter, and has a circular active area with a diameter of 1.5 mm on the top of which a 2-D array of piezoelectric transducer elements is...
journal article 2018
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Wu, Min (author), Springeling, Geert (author), Lovrak, M. (author), Mastik, Frits (author), Iskander-Rizk, Sophinese (author), Wang, Tianshi (author), Van Beusekom, Heleen M.M. (author), van der Steen, A.F.W. (author), van Soest, G. (author)
Lipid deposition can be assessed with combined intravascular photoacoustic/ultrasound (IVPA/US) imaging. To date, the clinical translation of IVPA/US imaging has been stalled by a low imaging speed and catheter complexity. In this paper, we demonstrate imaging of lipid targets in swine coronary arteries in vivo, at a clinically useful frame...
journal article 2017
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Gnanadesigan, Muthukaruppan (author), Hussain, Ali S. (author), White, Stephen (author), Scoltock, Simon (author), Baumbach, Andreas (author), van der Steen, A.F.W. (author), Regar, E.S. (author), Johnson, Thomas W. (author), van Soest, G. (author)
Lipid-core atherosclerotic plaques are associated with disease progression, procedural complications, and cardiac events. Coronary plaque lipid can be quantified in optical coherence tomography (OCT) pullbacks by measurement of lipid arcs and lipid lengths; parameters frequently used in clinical research, but labor intensive and subjective to...
journal article 2017
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Kruizinga, P. (author), Springeling, G. (author), Van Soest, G. (author), Van der Steen, A.F.W. (author), De Jong, N. (author), Robertus, J.L. (author), Van der Lugt, A. (author)
We introduce a method for photoacoustic imaging of the carotid artery, tailored toward detection of lipid-rich atherosclerotic lesions. A common human carotid artery was obtained at autopsy, embedded in a neck mimicking phantom and imaged with a multimodality imaging system using interstitial illumination. Light was delivered through a 1.25-mm...
journal article 2014
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Jansen, K. (author), Van Soest, G. (author), Van der Steen, A.F.W. (author)
The vulnerable atherosclerotic plaque is believed to be at the root of the majority of acute coronary events. Even though the exact origins of plaque vulnerability remain elusive, the thin-cap fibroatheroma, characterized by a lipid-rich necrotic core covered by a thin fibrous cap, is considered to be the most prominent type of vulnerable plaque...
journal article 2014
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Gnanadesigan, M. (author), Van Soest, G. (author), White, S. (author), Scoltock, S. (author), Ughi, G.J. (author), Baumbach, A. (author), Van der Steen, A.F.W. (author), Regar, E. (author), Johnson, T.W. (author)
Atherosclerotic plaque composition can be imaged using the optical attenuation coefficient derived from intravascular optical coherence tomography (OCT) data. The relation between optical properties and tissue type has been established on autopsy tissues. In this study, we validate an ex-vivo model for the effect of temperature and tissue...
journal article 2014
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Jansen, K. (author), Wu, M. (author), Van der Steen, A.F.W. (author), Van Soest, G. (author)
Spectroscopic intravascular photoacoustic imaging (sIVPA) has shown promise to detect and distinguish lipids in atherosclerotic plaques. sIVPA generally utilizes one of the two high absorption bands in the lipid absorption spectrum at 1.2 ?m and 1.7 ?m. Specific absorption signatures of various lipid compounds within the bands in either...
journal article 2014
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Jansen, K. (author), Van der Steen, A.F.W. (author), Wu, M. (author), Van Beusekom, H.M.M. (author), Springeling, G. (author), Li, X. (author), Zhou, Q. (author), Shung, K.K. (author), De Kleijn, D.P.V. (author), Van Soest, G. (author)
The natural history of atherosclerosis is marked by changes in the lipid biochemistry in the diseased arterial wall. As lesions become more vulnerable, different cholesterol species accumulate in the plaque. Understanding unstable atherosclerosis as a pharmacological and interventional therapeutic target requires chemically specific imaging of...
journal article 2014
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Jansen, K. (author), Wu, M. (author), Van der Steen, A.F.W. (author), Van Soest, G. (author)
The presence of lipids in atherosclerotic coronary lesions is an important determinant of their potential to trigger acute coronary events. Spectroscopic intravascular photoacoustic imaging (sIVPA) has the potential to automatically detect lipids in atherosclerotic lesions. For realtime in vivo imaging, limiting the number of excitation...
journal article 2013
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Maresca, D. (author), Jansen, K. (author), Renaud, G. (author), Van Soest, G. (author), Li, X. (author), Zhou, Q. (author), De Jong, N. (author), Shung, K.K. (author), Van der Steen, A.F.W. (author)
We demonstrate the feasibility of intravascular ultrasound (IVUS) chirp imaging as well as chirp reversal ultrasound contrast imaging at intravascular ultrasound frequency. Chirp excitations were emitted with a 34?MHz single crystal intravascular transducer and compared to conventional Gaussian-shaped pulses of equal acoustic pressure. The...
journal article 2012
Searched for: author:"van Soest, G."
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