Searched for: author:"van den Brekel, Michiel W.M."
(1 - 3 of 3)
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Vossen, David M. (author), Verhagen, Caroline V.M. (author), Van Der Heijden, Martijn (author), Essers, Paul B.M. (author), Bartelink, Harry (author), Verheij, Marcel (author), Wessels, L.F.A. (author), van den Brekel, Michiel W.M. (author), Vens, Conchita (author)
About half of advanced stage head and neck squamous cell carcinoma (HNSCC) patients can be cured by chemoradiotherapy. Patient outcome may be partially determined by the genetic alterations in HNSCC, rendering these alterations promising candidate prognostic factors and/or therapeutic targets. However, their relevance in patient outcome...
journal article 2019
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Langhout, Gerrit C. (author), Kuhlmann, Koert F.D. (author), Schreuder, Pim (author), Bydlon, Torre (author), Smeele, Ludi E. (author), van den Brekel, Michiel W.M. (author), Sterenborg, Henricus J.C.M. (author), Hendriks, B.H.W. (author), Ruers, Theo J.M. (author)
Background: Careful identification of nerves during head and neck surgery is essential to prevent nerve damage. Currently, nerves are identified based on anatomy and appearance, optionally combined with electromyography (EMG). In challenging cases, nerve damage is reported in up to 50%. Recently, optical techniques, like diffuse reflectance...
journal article 2018
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Vossen, David M. (author), Verhagen, Caroline V.M. (author), Grénman, Reidar (author), Kluin, Roelof J.C. (author), Verheij, Marcel (author), Van Den Brekel, Michiel W.M. (author), Wessels, L.F.A. (author), Vens, Conchita (author)
Background Large cancer genome studies continue to reveal new players in treatment response and tumorigenesis. The discrimination of functional alterations from the abundance of passenger genetic alterations still poses challenges and determines DNA sequence variant selection procedures. Here we evaluate variant selection strategies that...
journal article 2018