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Wronska, A.K. (author), van den Broek, M.A. (author), Perli, T. (author), de Hulster, A.F. (author), Pronk, J.T. (author), Daran, J.G. (author)
An oxygen requirement for de novo biotin synthesis in Saccharomyces cerevisiae precludes the application of biotin-prototrophic strains in anoxic processes that use biotin-free media. To overcome this issue, this study explores introduction of the oxygen-independent Escherichia coli biotin-biosynthesis pathway in S. cerevisiae. Implementation...
journal article 2021