Searched for: author:verhagen
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Barrett, Hilary E. (author), Meester, Eric J. (author), van Gaalen, Kim (author), van der Heiden, Kim (author), Krenning, Boudewijn J. (author), Beekman, F.J. (author), Verhagen, H. J. (author), de Jong, M. (author), Gijsen, F.J.H. (author)
Purpose: Atherosclerotic plaque development and progression signifies a complex inflammatory disease mediated by a multitude of proinflammatory leukocyte subsets. Using single photon emission computed tomography (SPECT) coupled with computed tomography (CT), this study tested a new dual-isotope acquisition protocol to assess each radiotracer...
journal article 2020
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Verhagen, K.J.A. (author), van Gulik, W.M. (author), Wahl, S.A. (author)
Redox metabolism plays an essential role in the central metabolic network of all living cells, connecting, but at the same time separating, catabolic and anabolic pathways. Redox metabolism is inherently linked to the excretion of overflow metabolites. Overflow metabolism allows for higher substrate uptake rates, potentially outcompeting...
review 2020
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Squazzoni, Flaminio (author), Polhillb, J. Gareth (author), Edmonds, Bruce (author), Ahrweiler, Petra (author), Antosz, Patrycja (author), Scholz, Geeske (author), Chappin, E.J.L. (author), Borit, Melania (author), Verhagen, Harko (author), Giardini, Francesca (author), Gilbert, Nigel (author)
The COVID-19 pandemic is causing a dramatic loss of lives worldwide, challenging the sustainability of our health care systems, threatening economic meltdown, and putting pressure on the mental health of individuals (due to social distancing and lock-down measures). The pandemic is also posing severe challenges to the scientific community, with...
journal article 2020
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Psychas, D.V. (author), Verhagen, S. (author)
The long convergence time required to achieve high-precision position solutions with integer ambiguity resolution-enabled precise point positioning (PPP-RTK) is driven by the presence of ionospheric delays. When precise real-time ionospheric information is available and properly applied, it can strengthen the underlying model and substantially...
journal article 2020
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Ma, H. (author), Verhagen, S. (author)
Precise point positioning (PPP) is one of the well-known applications of Global Navigation Satellite System (GNSS) and provides precise positioning solutions using accurate satellite orbit and clock products. The tropospheric delay due to the neutral atmosphere for microwave signals is one of the main sources of measurement error in PPP. As...
journal article 2020
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Haji Aghajany, S. (author), Amerian, Yazdan (author), Verhagen, S. (author), Rohm, Witold (author), Ma, H. (author)
The water vapor content in the atmosphere can be reconstructed using the all-weather condition troposphere tomography technique. In common troposphere tomography, the water vapor of each voxel is represented by an unknown parameter. This means that when the desired spatial resolution is high or study area is large, there will be a huge number of...
journal article 2020
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Zhao, X. (author), Verhagen, W.J.C. (author), Curran, R. (author)
The present study proposes an economic indicator to support the evaluation of aircraft End of Life (EoL) strategies in view of the increasing demand with regards to aircraft decommissioning. This indicator can be used to evaluate the economic performance and to facilitate the trade-off studies among different strategies. First, Disposal and...
journal article 2020
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Parappurath, Nikhil (author), Alpeggiani, F. (author), Kuipers, L. (author), Verhagen, Ewold (author)
Topological protection in photonics offers new prospects for guiding and manipulating classical and quantum information. The mechanism of spin-orbit coupling promises the emergence of edge states that are helical, exhibiting unidirectional propagation that is topologically protected against back scattering. We directly observe the topological...
journal article 2020
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Dignum, Frank (author), Dignum, Virginia (author), Davidsson, Paul (author), Ghorbani, A. (author), van der Hurk, Mijke (author), Jensen, Maarten (author), Kammler, Christian (author), Lorig, Fabian (author), Ludescher, Luis Gustavo (author), Melchior, Alexander (author), Mellema, René (author), Pastrav, Cezara (author), Vanhee, Loïs (author), Verhagen, Harko (author)
During the COVID-19 crisis there have been many difficult decisions governments and other decision makers had to make. E.g. do we go for a total lock down or keep schools open? How many people and which people should be tested? Although there are many good models from e.g. epidemiologists on the spread of the virus under certain conditions,...
journal article 2020
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Koornneef, H. (author), Verhagen, W.J.C. (author), Curran, R. (author)
When an aircraft experiences an unexpected issue during flight operations, a technician determines whether the aircraft can safely perform the next flight. This operational decision process - known as dispatch assessment - has to happen within limited available time between aircraft arrival and departure. Currently, technicians face two main...
journal article 2020
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Li, R. (author), Verhagen, W.J.C. (author), Curran, R. (author)
Remaining useful life (RUL) prediction is crucial for the implementation of Prognostics and Health Management (PHM) systems, enabling application of predictive maintenance strategies for critical systems (e.g. in aviation, power, railway). Existing literature addresses aspects of data-driven prognostic approaches, with a predominant focus on...
conference paper 2019
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Koornneef, H. (author), Verhagen, W.J.C. (author), Curran, R. (author)
Delays are costly to airlines in both money and image. A significant number of delays is caused by unexpected technical failures of aircraft systems or components. These failures, if not dealt with efficiently, can cause disruptions in the flight schedule and network. The annual costs of these type of disruptions add up to an estimated cost...
conference paper 2019
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Psychas, D.V. (author), Verhagen, S. (author), Liu, X. (author), Memarzadeh, Y. (author), Visser, H. (author)
This paper presents an analysis of the ionospheric corrections required to get a significant improvement in PPP-RTK performance. The main aim was to determine the improvement in the position precision and Time-To-First-Fix in the PPP-RTK user side using ionospheric corrections computed from a network. The study consists of two main steps. The...
journal article 2019
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Psychas, D.V. (author), Verhagen, S. (author), Liu, Xianglin (author)
poster 2019
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Psychas, D.V. (author), Verhagen, S. (author), Liu, Xianglin (author)
abstract 2019
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Wognum, P.M. (author), Bil, Cees (author), Elgh, Fredrik (author), Peruzzini, Margherita (author), Stjepandić, Josip (author), Verhagen, W.J.C. (author)
Transdisciplinary processes have been the subject of research since several decades already. Transdisciplinary processes are aimed at solving ill-defined and socially relevant problems. Many researchers have studied transdisciplinary processes and have tried to understand the essentials of transdisciplinarity. Many engineering problems can be...
journal article 2019
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Verhagen, H.J. (author)
In this paper, protection options for a high-value, industrial area along the coast of West Bengal (India) are investigated. The options are designed to protect against cyclone surges with a probability of 1/100 per year. Two alternatives are compared, a classical solution of a dike with a revetment and a solution with a mangrove belt in...
journal article 2019
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Vossen, David M. (author), Verhagen, Caroline V.M. (author), van der Heijden, Martijn (author), Essers, Paul B.M. (author), Bartelink, Harry (author), Verheij, Marcel (author), Wessels, L.F.A. (author), van den Brekel, Michiel W.M. (author), Vens, Conchita (author)
About half of advanced stage head and neck squamous cell carcinoma (HNSCC) patients can be cured by chemoradiotherapy. Patient outcome may be partially determined by the genetic alterations in HNSCC, rendering these alterations promising candidate prognostic factors and/or therapeutic targets. However, their relevance in patient outcome...
journal article 2019
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Narayanan, Prasobh (author), Verhagen, W.J.C. (author), Dhanisetty, V.S.V. (author)
Airline operators face accidental damages on their fleet of aircraft as part of operational practice. Individual occurrences are hard to predict; consequently, the approach towards repairing accidental damage is reactive in aircraft maintenance practice. However, by aggregating occurrence data and predicting future occurrence rates, it is...
journal article 2019
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Newcamp, Jeffrey (author), Verhagen, W.J.C. (author), Santos, Bruno F. (author), Curran, R. (author)
Military aircraft retirements are an afterthought for many lifecycle planners. More active management of end-of-life fleets can yield increased confidence in fleet capability and retirement timelines. This work provides fleet managers with a tool to manage remaining aircraft flight hours to yield a desired fleet retirement pattern. It solves...
journal article 2019
Searched for: author:verhagen
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