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Koppenol, D.C. (author), Vermolen, F.J. (author), Koppenol-Gonzalez, Gabriela V. (author), Niessen, Frank B. (author), van Zuijlen, Paul P.M. (author), Vuik, C. (author)
A continuum hypothesis-based model is developed for the simulation of the contraction of burns in order to gain new insights into which elements of the healing response might have a substantial influence on this process. Tissue is modeled as a neo-Hookean solid. Furthermore, (myo)fibroblasts, collagen molecules, and a generic signaling molecule...
journal article 2016
document
Koppenol, D.C. (author), Vermolen, F.J. (author), Niessen, Frank B. (author), van Zuijlen, Paul P.M. (author), Vuik, C. (author)
A continuum hypothesis-based, biomechanical model is presented for the simulation of the collagen bundle distribution-dependent contraction and subsequent retraction of healing dermal wounds that cover a large surface area. Since wound contraction mainly takes place in the dermal layer of the skin, solely a portion of this layer is included...
journal article 2016
document
Koppenol, D.C. (author), Vermolen, F.J. (author), Niessen, Frank B. (author), van Zuijlen, Paul P.M. (author), Vuik, C. (author)
A continuum hypothesis-based model is presented for the simulation of the formation and the subsequent regression of hypertrophic scar tissue after dermal wounding. Solely the dermal layer of the skin is modeled explicitly and it is modeled as a heterogeneous, isotropic and compressible neo-Hookean solid. With respect to the constituents of the...
journal article 2016