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Van der Put, T.A.C.M. (author)This chapter discusses the theory of fracture mechanics based on the flat elliptical crack; the derivation of the mixed "mode I - II" - interaction equation, with the relations between the mode I and mode II stress intensities and energy release rates, based on an orthotropic-isotropic transformation of the Airy stress function; the derivation...book chapter 2011
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Daran, J.M. (author), Pronk, J.T. (author), Driessen, A.J.M. (author), Nijland, J.G. (author), Lamboo, F. (author), Puig-Martinez, M. (author), Veiga, T. (author), Gombert, A.K. (author)Penicillium chrysogenum is widely used as an industrial antibiotic producer, in particular in the synthesis of ß-lactam antibiotics such as penicillins and cephalosporins. In industrial processes, oxalic acid formation leads to reduced product yields. Moreover, precipitation of calcium oxalate complicates product recovery. We observed oxalate...journal article 2011
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Stallinga, S. (author)A theory of optical trapping at low Numerical Aperture (NA) is presented. The theory offers an analytical description of the competition between the stabilizing gradient and destabilizing scattering force. The trade-off can be characterized by a single dimensionless trapping parameter, which increases with bead size to wavelength ratio ?/?, m,...journal article 2011
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Bakker, J.J.W. (author), Zieverink, M.M.P. (author), Kapteijn, F. (author), Moulijn, J.A. (author), Kreutzer, M.T. (author)Segmented flow in standard GC capillary columns, with a heterogeneous Pd catalyst on the walls, gave rapid information about catalytic processes in them. The residence time and conversion was monitored visually, greatly simplifying bench-scale optimization. Examples show the benefits of the elimination of pore diffusion and axial dispersion....journal article 2011
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Bitenc, M. (author), Lindenbergh, R.C. (author), Khoshelham, K. (author), Van Waarden, A.P. (author)The Dutch coast is characterized by sandy beaches flanked by dunes. Understanding the morphology of the coast is essential for defense against flooding of the hinterland. Because most dramatic changes of the beach and the first dune row happen during storms, it is important to assess the state of the coast immediately after a storm. This is...journal article 2011
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Boender, L.G.M. (author), Almering, M.J.H. (author), Dijk, M. (author), Van Maris, A.J.A. (author), De Winde, J.H. (author), Pronk, J.T. (author), Daran-Lapujade, P. (author)Cultivation methods used to investigate microbial calorie restriction often result in carbon and energy starvation. This study aims to dissect cellular responses to calorie restriction and starvation in Saccharomyces cerevisiae by using retentostat cultivation. In retentostats, cells are continuously supplied with a small, constant carbon and...journal article 2011
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Dunning, A.G. (author), Tolou, N. (author), Herder, J. (author)For many applications in precision engineering, a six degrees of freedom (DoF) compliant stage (CS) with zero stiffness is desirable, to deal with problems like backlash, friction, lubrication, and at the same time, reduce the actuation force. To this end, the compliant stage (also known as compliant mechanism) can be statically balanced with a...journal article 2011
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Nijhuis, S. (author), Van Lammeren, R. (author), Van der Hoeven, F. (author)Exploring the Visual Landscape is about the combination of landscape research and planning, visual perception and Geographic Information Science. It showcases possible ways of getting a grip on themes like: landscape openness, cluttering of the rural landscape, high-rise buildings in relation to cityscape, historic landscapes and motorway...book 2011
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- Mooij, E. (author), Ellenbroek, M. (author) book chapter 2011
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Boender, L.G.M. (author), Van Maris, A.J.A. (author), De Hulster, E.A.F. (author), Almering, M.J.H. (author), Van der Klei, I.J. (author), Veenhuis, M. (author), De Winde, J.H. (author), Pronk, J.T. (author), Daran-Lapujade, P.A.S. (author)Extremely low specific growth rates (below 0.01 h?1) represent a largely unexplored area of microbial physiology. In this study, anaerobic, glucose-limited retentostats were used to analyse physiological and genome-wide transcriptional responses of Saccharomyces cerevisiae to cultivation at near-zero specific growth rates. While quiescence is...journal article 2011
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Veiga, T. (author), Solis-Escalante, D. (author), Romagnoli, G. (author), Ten Pierick, A. (author), Hanemaaijer, M. (author), Deshmuhk, A. (author), Wahl, A. (author), Pronk, J.T. (author), Daran, J.M. (author)The industrial production of penicillin G by Penicillium chrysogenum requires the supplementation of the growth medium with the side chain precursor phenylacetate. The growth of P. chrysogenum with phenylalanine as the sole nitrogen source resulted in the extracellular production of phenylacetate and penicillin G. To analyze this natural pathway...journal article 2011
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Caratelli, D. (author), Yarovoy, A. (author)Ground-penetrating radar (GPR) technology finds applications in many areas such as geophysical prospecting, archaeology, civil engineering, environmental engineering, and defence applications as a non-invasive sensing tool [3], [6], [18]. One key component in any GPR system is the receiver/transmitter antenna. Desirable features for GPR antennas...book chapter 2011
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Molenbroek, J.F.M. (author), Mantas, J. (author), De Bruin, R. (author)This book addresses the topic of toilet design, but instead of focusing on the typical able bodied user, it takes the various needs and limited abilities of older and/or disabled people as its starting point (human centered design). This follows the principles of ‘Inclusive Design’: designs taking into account the needs of the most challenged,...book 2011
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Simi, M. (author), Tolou, N. (author), Valdastri, P. (author), Herder, J.L. (author), Menciassi, A. (author), Dario, P. (author)A novel compliant Magnetic Levitation System (MLS) for a wired miniature surgical camera robot was designed, modeled and fabricated. The robot is composed of two main parts, head and tail, linked by a compliant beam. The tail module embeds two magnets for anchoring and manual rough translation. The head module incorporates two motorized donut...journal article 2012
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Wang, Y. (author), Leus, G.J.T. (author)Low-complexity least-squares (LS) estimators based on time-of-arrival (TOA) or time-difference-of-arrival (TDOA) measurements have been developed to locate a target node with the help of anchors (nodes with known positions). They require to select a reference anchor in order to cancel nuisance parameters or relax stringent synchronization...journal article 2012
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Nijkamp, J.F. (author), Van den Broek, M.A. (author), Datema, E. (author), De Kok, S. (author), Bosman, L. (author), Luttik, M.A.H. (author), Daran-Lapujade, P.A.S. (author), Vongsangnak, W. (author), Nielsen, J. (author), Heijne, W.H.M. (author), Klaassen, P. (author), Paddon, C.J. (author), Platt, D. (author), Kötter, P. (author), Van Ham, R.C. (author), Reinders, M.J.T. (author), Pronk, J.T. (author), De Ridder, D. (author), Daran, J.M. (author)Saccharomyces cerevisiae CEN.PK 113-7D is widely used for metabolic engineering and systems biology research in industry and academia. We sequenced, assembled, annotated and analyzed its genome. Single-nucleotide variations (SNV), insertions/deletions (indels) and differences in genome organization compared to the reference strain S. cerevisiae...journal article 2012
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Löschberger, A. (author), Van de Linde, S. (author), Debauvalle, M.C. (author), Rieger, B. (author), Heilemann, M. (author), Krohne, G. (author), Sauer, M. (author)One of the most complex molecular machines of cells is the nuclear pore complex (NPC), which controls all trafficking of molecules in and out of the nucleus. Because of their importance for cellular processes such as gene expression and cytoskeleton organization, the structure of NPCs has been studied extensively during the last few decades,...journal article 2012
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Stallinga, S. (author), Rieger, B. (author)We introduce a method for determining the position and orientation of fixed dipole emitters based on a combination of polarimetry and spot shape detection. A key element is an effective Point Spread Function model based on Hermite functions. The model offers a good description of the shape variations with dipole orientation and polarization...journal article 2012
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Lian, X. (author), Nikookar, H. (author), Ligthart, L.P. (author)Cognitive radio (CR) is an intelligent radio system and is able to share the spectrum with licensed users (LU). By adopting adaptive beam forming techniques, CR can reuse the spectrum with LU via directing main beams towards CR users while displaying nulls towards LU. In this article, we present a new distributed beam forming (DB) technique, and...journal article 2012
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A wide spectral range single-photon avalanche diode fabricated in an advanced 180 nm CMOS technologyMandai, S. (author), Fishburn, M.W. (author), Maruyama, Y. (author), Charbon, E. (author)We present a single-photon avalanche diode (SPAD) with a wide spectral range fabricated in an advanced 180 nm CMOS process. The realized SPAD achieves 20 % photon detection probability (PDP) for wavelengths ranging from 440 nm to 820 nm at an excess bias of 4V, with 30 % PDP at wavelengths from 520 nm to 720 nm. Dark count rates (DCR) are at...journal article 2012