Searched for: contributor%3A%22Accardo%2C+A.+%28mentor%29%22
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Cussen, Kai (author)
Thermo-responsive hydrogels are a class of smart material that show increasing promise and applications in the biomedical engineering industry. This thesis investigated a thermo-responsive hydrogel for 4D printing applications. A poly(N-isopropylacrylamide) (>97%) (pNIPAM) based hydrogel was developed and the concentration of NIPAM, as well...
master thesis 2024
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Ayman Ahmed Mubeen, AYMAN AHMED MUBEEN (author)
Shape morphing is a prevalent feature in all living organisms. Incorporating shape-morphing capabilities into engineered scaffolds in the field of tissue engineering by virtue of 4D printing would allow for structures to closely mimic in-vivo conditions, and dynamically interact with changing cellular microenvironments. Engineered scaffolds...
master thesis 2023
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kadel, Himanshu (author)
The brain is the most intricate organ in the human body, yet the underlying mechanisms of its cells and networks are not fully mapped. In addition to this lack of understanding, there are numerous neurological disorders and diseases for which a cure remains elusive. There has been persistent research to understand how neuronal cells function...
master thesis 2023
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Kuo, Chihao (author)
master thesis 2023
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Michalica, Thomas (author)
3D-multi-electrode arrays (3D-MEAs) are needed to overcome the limitations of 2D-multi-electrode arrays (2D-MEAs) and enable the electrical characterization of 3D neuronal cultures in in vitro brain models, advancing the understanding of neurological disorders and paving the way to personalized medicine. The aim of this thesis was to overcome...
master thesis 2023
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Veldkamp, Dian (author)
The central nervous system has a very limited capacity to regenerate damaged tissue. Therefore, regeneration strategies focus on transplantation of neural stem cells or differentiated neural cells. In order to make such a treatment effective, it is important to understand the mechanisms that enable cell differentiation. It is well known that...
master thesis 2022
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Roos, Brian (author)
Microglia, the resident macrophages of the central nervous system, are key players in neuroinflammation and neurodegenerative diseases, such as Alzheimer’s and Parkinson’s. These cells represent promising cellular targets for therapeutic intervention, therefore a detailed cellular biological knowledge of microglia is of paramount importance....
master thesis 2021
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Barin, Nastaran (author)
Glioblastoma (GBM) is the most aggressive and malignant brain tumor with no effective treatment available so far. A major obstacle in GBM research is the lack of reliable in vitro models that can mimic the tumor cellular environment. The goal of this study was to develop a 3D-engineered scaffold as a new cell culture model capable of providing a...
master thesis 2021
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Akolawala, Qais (author)
Glioblastoma (GBM) is a devastating cancer of the brain with an extremely poor prognosis. Novel <i>in-vitro</i> methods for the assessment of cancer response to drugs and radiation are being developed. Compared to two-dimensional cell culture, three-dimensional cellular microenvironments provide a model closer to the <i>in-vivo</i> situation. In...
master thesis 2021
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