Data-Driven Material Characterisation of Multicomponent Atherosclerotic Arteries

Cardiovascular diseases continue to be the primary cause of death worldwide, where the buildup of plaque within arterial walls, known as atherosclerosis, is a major contributor to various acute cardiovascular events. Determining the material properties and the resulting stress distributions is crucial in the risk assessment of atherosclerotic...

The Mechanical and Chemical Characterization of a 3D Printed Ear Implant

Material property characterisation of tissue engineered fibrous cap structures: An inverse Finite Element study

Introduction: Atherosclerosis is characterised by the buildup of plaque within the arterial wall and it is often the underlying cause effect of deaths related to cardiovascular diseases. Thin cap fibroatheromas are plaques with a high risk of causing clinical events due to rupture and espousal of thrombogenic components to the bloodstream. The...

Development of an anisotropic hyperelastic model with damage for the mechanical behaviour of arterial wall tissue

Cardiovascular disease has caused 3.9 million deaths in Europe and over 1.8 million deaths in the European Union, which accounts for 45\% of all deaths in Europe and 37\% of all death in the European Union in 2017. Cardiovascular disease is mainly caused by atherosclerosis. Atherosclerosis is a kind of disease where the inside of the artery gets...

A Novel Approach to Estimating the Material Properties of Atherosclerotic Plaque Tissue

The majority of cardiovascular clinical events, which are the main causes of mortality and morbidity worldwide, are caused by atherosclerotic plaque rupture. This biomechanical event occurs when the local plaque stresses exceed its strength. The plaque stresses can be assessed by computational models to predict these events. Current approaches...