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Kan, Matthijs (author)In spinal surgery, the misplacement of spinal screws is a common problem that causes (severe) pain, bleedings or even paralysis [1] [2] [3]. In order to improve the navigational support of spine surgeons, this research focuses on the development of an optical sensing diffuse reflectance spectroscopy (DRS) orthopaedic drill that identifies bone...student report 2020
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van Berckel, Pieter (author)Previous studies show that the smart electrosurgical knife, which adds diffuse reflectance spectroscopy to the traditional electrosurgical knife, is a promising technique for breast-conserving surgery, namely it enables real-time tissue characterization while cutting. More specifically, based on the fat/water-ratio, it enables intraoperative...master thesis 2020
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van Dommelen, Ayla (author)During pathogenesis the microstructure and organization of tissue changes and this is reflected in the scattering behaviour. Optical Coherence Tomography (OCT) provides information about tissue morphology by measuring backscattered light and has the potential to enhance optical images with quantitative optical parameters, without the need to...master thesis 2020
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van Trier, Teun (author)The operating room and central sterile supply department (CSSD) are two<br/>resource-intensive healthcare departments. Reducing the environmental and financial impact of these departments is of great importance in the global debate on sustainability. Removing unnecessary items from instrument trays may provide a partial solution. However,...master thesis 2019
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Hoeboer, Max (author)Urinary schistosomiasis is with over 110 million infected people one of the most common parasitic infections worldwide, most commonly found in Sub-Saharan Africa. Urinary schistosomiasis is caused by the Schistosoma Haematobium (SH) parasite. The most common diagnostic method is manual microscopy, in which urine is manually examined to see...master thesis 2019
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van der Plaats, Lisa (author)The quality of rigid endoscopes deteriorates during clinical use due to the sterilization process, mechanical forces and wear and tear during regular use. Regulations and standards on ensuring the quality of these instruments are currently non-existent or contain only qualitative measures, resulting in subjective examinations . Defective rigid...master thesis 2019
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Grandia, Leander (author)Atrial Fibrillation (AF) is a common type of arrhythmia, characterized by rapid and irregular contraction of the atria. Irregular contraction of the atria is caused by erroneous electrical activation, originating from the tissue around the Pulmonary Veins (PV) in the Left Atrium (LA). Catheter-based treatment of AF includes ablation of the...master thesis 2019
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Engelen, Myrthe (author)Survival in lung cancer patients relies on correct intraoperative identification and resection of lung nodules. We hypothesize that epidermal growth factor receptor-targeted (EGFR) intraoperative molecular imaging can help improve localization of lung nodules. In a clinical study, we evaluated the use of panitumumab-IRDye800 to determine if...master thesis 2019
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Tazelaar, Eliane (author)Background: To find treatment options for lower back pain, one must gain insight in the spinal anatomy and biomechanics such as joint reaction forces and movement strategies. These can be acquired with use of the Finite Element Method. Previously investigated finite element models of the lumbar intervertebral disc have been designed with the...master thesis 2019
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Dessing, Olaf (author)embargomaster thesis 2019
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D'Aquino, Francesco (author)The problem of premature births is widespread throughout the world affecting 41000 newborns daily; the issues that follow, often related to breathing, require the use of mechanical ventilation to compensate for the poor compliance of the respiratory muscles of newborns. However, side effects associated with artificial ventilation, including...master thesis 2019
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van Gent, Carlijn (author)During use of the smart electrosurgical knife, deterioration of the diffuse reflectance spectroscopy (DRS) signal intensity obstructs proper distinction between tissues. In order to reduce signal loss, this research has focused on the influence of smart electrosurgery on both the morphology and composition of the layer covering the optical fiber...master thesis 2019
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Jong, Lynn-Jade (author)Transvenous lead extractions (TLEs) are minimally invasive procedures in which pacing or implantable cardioverter defibrillator leads are extracted under guidance of 2D X-ray fluoroscopy. Despite the fact that fluoroscopy is currently the gold standard for TLEs, it has several limitations in terms of visualization of anatomical structures, areas...master thesis 2019
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Brouwer, Max (author)Expanded Criteria Donor (ECD) organs are being used more often in clinical setting. The regenerative ability of the organs might be able to restore the organ to full functionality ex vivo. For long term kidney stabilization, optimization and monitoring an organ incubator is preferable. However, it is unclear which available parts would work best...master thesis 2019
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GEZER, GÜROL (author)As a nonlinear alternative to the linear interpretation of arterial blood pressure waveform, soliton theory has been proposed to model arterial blood pressure by interpreting the pulsatile nature of pressure pulses in the viewpoint of soliton transmission. The existing solitary wave literature supports this interpretation by deriving Korteweg-de...master thesis 2019
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de Ridder, Else (author)Sustainability is becoming more important in numerous industries, including healthcare. Action to achieve sustainability is undertaken by various means, such as the Green Deal Healthcare. Several tools exist that can assess the environmental impact of a certain industry or company, but no tools exist that aid in actively lowering this...master thesis 2018
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Berendsen, Jasmijn (author)The medical device market is continuously innovating to improve the outcome in the treatment of patients. One of these innovations is minimally invasive robot-assisted surgical systems to assist in performing laparoscopic surgical procedures and to allow surgeons to perform the most complex and delicate surgeries with pinpoint precision in very...master thesis 2018
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Wesselink, Vincent (author)Every year over 30.000 patients in the Netherlands alone are operated to repair a damaged meniscus. Damage to the meniscus occurs due to a combination of excessive torque and compression forces on the knee joint. The current arthroscopic cutters that are used during meniscectomies can only reach limited areas of the meniscus. During the...master thesis 2018
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Cranz, Felix (author)Introduction: Over five billion people in mainly low and middle income countries (LMICs) do not have access to safe surgery. This is due to a lack of available and functional medical equipment, where up to 70% of the existing equipment is broken. Some reasons for this shortage in medical equipment are a lack of funding, maintenance, training,...master thesis 2018
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van Griethuijsen, Philip (author)Implanted intra-peritoneal insulin infusion (‘i4’) devices administer insulin into the peritoneum of diabetic patients with extreme blood glucose swings, that are highly difficult to control. The flushing procedures of i4 devices to clear obstructions from its conduits caused by insulin degradation are not always fully effective. The goal of...master thesis 2017