Organ-on-Silicon

The cost and the development time of pharamecutical products are often severely affected by the in vitro tests currently employed in pharmaceutical R&D. These assays are often failing to accurately recapitulate diseases and to predict human responses to new medicines. Organ-on-Chip (OOC) devices are designed to result in advanced in vitro...

Free standing interconnects for stretchable electronics

Advancements in stretchable electronic systems have changed the way modern electronics interact with their target systems, by their conformability to more complex shapes as compared to conventional rigid or flexible electronics. By utilizing this, limitless applications in the field of healthcare can be realized, such as wearable and implantable...

Stretchable Micro-Electrode Arrays for Electrophysiology

A potential serious side effect of drugs is cardiotoxicity which can result in lethal heart arrhythmias. Cardiotoxicity has been the leading cause of drug withdrawals from the market in the past decades, and has been responsible for costly failures in late stage clinical trials. This highlights the unmet need in the pharmaceutical industry for...

SiGe heterojunction bipolar transistors with Schottky collector contacts

Flexible Sensors for Minimally Invasive Medical Instruments

Being able to measure medical parameters directly inside the body in a minimally invasive way allows for a more accurate, faster, safer and cheaper diagnosis. A typical example can be found in the diagnosis of coronary artery diseases, where simultaneous measurement of intracoronary blood flow and pressure is needed. The aim of this Thesis is to...

MEMS Integration Techniques on Silicon-On-Insulator for Inertial Devices

Electronics on Flexible and Stretchable Silicon Arrays

Hub exchange operations in intermodal hub-and spoke networks: A performance comparison of rail-rail exchange facilities

The implementation of hub-and-spoke networks in intermodal transport is suggested as one of the potential solutions for helping to increase the intermodal market share. Traditionally, trains are shunted at hubs; this is a time-consuming process. Since the early 1990s a new type of intermodal terminal, specifically designed for fast tran-shipment...