Searched for: contributor%3A%22Hanefeld%2C+U.+%28promotor%29%22
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Coloma Hurel, J.L. (author)
The utilisation of flow chemistry and immobilisation in biocatalysis is gaining attention as an attractive way to overcome some of the limitations commonly reported in traditional batch systems such as mass transfer restrictions, low productivities, substrate/product inhibition and safety, among others....
doctoral thesis 2022
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Godoy Hernandez, A. (author)
The rise of multi-drug resistant bacterial infections is a worldwide growing concern. Despite being one of the greatest medical advances of the 20th century, classical antibiotics are no longer effective against such organisms. Unfortunately, patients infected with drug-resistant bacteria are more likely to experience worse clinical outcomes, as...
doctoral thesis 2022
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Mayer, F. (author)
Since lanthanides were discovered in the 18th century, they fascinate scientists due to their similarity in chemical behavior and versatility in physical properties. It is thus not surprising, that lanthanides are part of uncountable applications in modern industry, electronics, magnets, light sources and medical applications. Especially, as the...
doctoral thesis 2021
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Marsden, S.R. (author)
Thiamine diphosphate dependent enzymes are excellent catalysts for the asymmetric synthesis of the α-hydroxyketone (acyloin) structural motif, which is found in many pharmaceuticals and fine chemicals. In chapter 2, variants of transketolase from Saccharomyces cerevisiae were screened for the conversion of aliphatic aldehydes with...
doctoral thesis 2021
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Mestrom, L. (author)
Enzymes are nature’s catalyst of choice for the highly selective and efficient coupling of carbohydrates. Enzymatic sugar coupling is a competitive technology for industrial glycosylation reactions, since chemical synthetic routes require extensive use of laborious protection group manipulations and often lack regio- and stereoselectivity.
doctoral thesis 2020
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Busch, H. (author)
Water addition reactions to (un)-activated double bonds are very rewarding reactions as they elegantly introduce a hydroxyl-group thereby often adding value to the generated product by establishing a novel stereocentre in tertiary, chiral alcohols. However, performing selective water addition reactions is an extremely challenging task using...
doctoral thesis 2020
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ten Dam, J. (author)
The production of renewable chemicals is gaining attention over the past few years. The natural resources from which they can be derived in a sustainable way are most abundant in sugars, cellulose and hemi cellulose. These highly functionalized molecules need to be de-functionalized in order to be feedstocks for the chemical industry. A...
doctoral thesis 2016
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Mueller, T. (author)
doctoral thesis 2016
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Chen, B. (author)
?-Hydroxy carbonyl compounds are an important class of compounds often found as a common structural motif in natural products. Although the molecules themselves look rather simple, their synthesis can be challenging. Water addition to conjugated C = C bonds opens up a straightforward route for the preparation of ?-hydroxy carbonyl compounds....
doctoral thesis 2015
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Cabirol, F.L. (author)
In this thesis I have addressed several issues related to the HNL-catalyzed preparation of cyanohydrins. I first demonstrated in Chapter 2 that immobilized HNL as sol-gels and as commercially available Cross Linked Enzyme Aggregates (CLEA®) improved several features of the biocatalyst such as solvent stability, and substrate or product...
doctoral thesis 2010
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