Searched for: contributor%3A%22Heijnen%2C+J.J.+%28promotor%29%22
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Schumacher, R. (author)
This thesis deals with increasing the free energy conservation in<br/>chemotropic microorganisms with emphasis on S. cerevisiae and investigates<br/>a number of different aspects related to industrial fermentation processes.
doctoral thesis 2018
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da Fonte Lameiras, F. (author)
Filamentous fungi, especially from the genus Aspergillus, are well known for the<br/>production of organic acids in fermentation industry. Nonetheless, in present time the competing chemical conversion routes are still more profitable, leaving space for further investigations and improvement on the biological routes.
doctoral thesis 2018
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Shah, M.V. (author)
doctoral thesis 2016
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Cueto Rojas, H.F. (author)
doctoral thesis 2016
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de Jonge, L.P. (author)
doctoral thesis 2016
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Heeres, A.S. (author)
doctoral thesis 2016
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Suarez-Mendez, C.A. (author)
Production of chemicals via biotechnological routes are becoming rapidly an alternative to oil-based processes. Several microorganisms including yeast, bacteria, fungi and algae can transform feedstocks into high-value molecules at industrial scale. Improvement of the bioprocess performance is a key factor for making this technology economically...
doctoral thesis 2015
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Schmal, J.P. (author)
Dynamic chemical process modelling is still largely considered an art. In this thesis the theory of large-scale chemical process modelling and validation is discussed and initial steps to extend the theory are explored. In particular we pay attention to the effect of the level of detail on the model simulation and optimisation performance. We...
doctoral thesis 2014
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Jamalzadeh, E. (author)
doctoral thesis 2013
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Braga da Cruz, A.L. (author)
Temperature is an environmental parameter that greatly affects the growth of microorganisms, due to its impact on the activity of all enzymes in the network. This is particularly relevant in habitats where there are large temperature changes, either daily or seasonal. Understanding how organisms have adapted to cope with these temperature-cycles...
doctoral thesis 2013
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Deshmukh, A.T. (author)
Even 80 years after the discovery of penicillin, it still holds 16% of total antibiotics market. This makes it crucial, from an economical point of view, to improve our understanding of the production organism Penicillium chrysogenum to maximize the penicillin production, as its theoretical yields are far from reached. With the advancement in...
doctoral thesis 2013
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Verdoold, S. (author)
ElectroHydroDynamic Atomisation (or electrospraying) is a way to disperse a liquid into droplets by exposing it to a strong electric field. The resulting droplets are (highly) charged and can exhibit narrow size and charge distributions which is desirable for many applications. In this dissertation a novel method is developed to classify the...
doctoral thesis 2012
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Zhao, Z. (author)
doctoral thesis 2011
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Douma, R.D. (author)
Penicillin has been produced on an industrial scale for several decades. The improvements in its production process, in terms of product yields and production rates, present an unprecedented success in fermentation technology. However, the obtained product yields still remain far from their theoretical maximum. More insight in the regulation of...
doctoral thesis 2010
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Taymaz Nikerel, H. (author)
Kinetic models, which predict the behaviour of metabolic reaction networks under different conditions, are indispensible to fully and quantitatively understand the relation between a product pathway and connected central metabolism. In this thesis the focus was to develop tools for future in vivo kinetic modeling in Escherichia coli. The...
doctoral thesis 2010
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Canelas, A.C.B.D. (author)
The quantitative analysis of enzyme kinetics in vivo, leading to the construction of predictive kinetic models of metabolic reaction networks, is an old ambition in Biochemistry and a central goal within the emerging field of Systems Biology. However, this objective remains largely unfulfilled because of a fundamental problem: the gap between...
doctoral thesis 2010
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Nikerel, I.E. (author)
The study on biological systems attracts more and more interest since these systems offer interesting solutions to problems in diverse areas ranging from sustainable production of chemicals and fuels, environmental problems to medical questions. This thesis is concerned with the effort of improving our current understanding on how the cellular...
doctoral thesis 2009
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Cuellar Soares, M.C. (author)
Industrial biotechnology can be defined as the utilization of living organisms or their enzymes for the industrial production of food, beverages, commodity chemicals and pharmaceuticals, among others. A biotechnological production process, so-called bioprocess, mostly comprises product formation (e.g. by fermentation) and product recovery and...
doctoral thesis 2008
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Aboka, F.O. (author)
doctoral thesis 2008
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Van Leeuwen, M. (author)
doctoral thesis 2008
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