The effect of scaffolds with a negative, zero, or positive Poisson’s ratio on pre-osteoblastic (MC3T3-E1) cell response

Bone tissue engineering (BTE) researches the characteristics which are needed to create the ultimate bone scaffold which enhances cell response. Limited research has been done regarding the effect of the Poisson’s ratio on the scaffold-cell interaction. In this graduation project we therefore explore the cell response on scaffolds with a...

New implant acetabular cup: A biomechanical proof of concept

The management of large acetabular defects remains one of the most challenging aspects of revision total hip arthroplasties. Failure of frequently used acetabular reconstruction components are, among others, caused by the lack of biological fixation, a non-physiological stress distribution and stress-shielding. Attempting to diminish these...