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Kolthof, Roos (author)
<b>Background</b><br/>Spasticity is a condition that affects patients who have sustained an upper motor neuron lesion. Such lesions include for example cerebral palsy (CP), of which 35% is affected by spasticity, and stroke, of which 90% is affected by spasticity. Pharmacological therapy often involves the prescription of oral baclofen. However,...
master thesis 2024
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van Dam, Nathalie (author)
Propulsion power is an important metric in wheelchair racing. For a flat surface, it can be estimated from the sum of friction power and kinetic power. Usually, to determine friction power, the rolling and air drag coefficient first need to be determined with coast-down tests or other time-consuming methods. The aim of this paper was to...
master thesis 2023
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Formsma, Bart (author)
<b>Introduction</b> Traumatic brain injury (TBI) is a leading cause of childhood morbidity, disability and mortality worldwide. In the treatment of TBI, neuromonitoring is essential to prevent secondary neurological damage. However, the use of neuromonitoring and specifically therapeutic targets is currently limited evidence-based.<br/><b...
master thesis 2022
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van Lange, Eline (author)
Background: Complex regional pain syndrome (CRPS) is a clinical disorder characterized by continuous, disproportionate pain and sensory, vasomotor, sudomotor and motor trophic changes. CRPS patients have a heterogeneous clinical picture caused by multiple underlying pathophysiology mechanisms including inflammation, vasomotor disturbances and...
master thesis 2022
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Lemmers, Danny (author)
Reflex mechanisms are an efficient method humans use to deal with mechanical disturbances in daily life. In the muscle we see two reflexes, the M1 reflex and the M2 reflex. The M2 reflex is cortically modulated and is affected by intention<br/>and habituation. A lot of research has been conducted on understanding the M2 reflexes, their origin...
master thesis 2022
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Giri, Natasha (author)
People can learn voluntary regulation of certain brain rhythms with help of real-time feedback through a brain-computer interface. Modulation of brain rhythms associated with movement, also known as sensorimotor rhythms (SMR), has shown to alter excitability of the spinal cord. This may indicate a potential role of the SMR in reflex modulation....
master thesis 2022
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Mulder, Babette (author)
Background: Determining how the reflex voluntarily modulates while performing activities of daily living (ADL), and understanding how this modulation might differ between healthy subjects and patients with motor disorders, can aid in developing a rehabilitative program to improve the functional performance of thewrist. The current study designs...
master thesis 2021
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Bansal, Ishita Rai (author)
Resting-state functional magnetic resonance imaging (rs-fMRI) is one of the promising non-invasive technology that helps in the detection of neurodegenerative and neurological disorders, localisation of the different areas of the brain and understanding the connectivity between them. It involves the acquisition of time series of MR images while...
master thesis 2021
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Boogaard, Menno (author)
Human force proprioception has previously been shown to be important in manual control tasks. Recent experiments suggest that force proprioception is more accurate than position proprioception. Still, knowledge about proprioceptive qualities and their relevance in manual control is lacking or inconsistent. This research aims to experimentally...
master thesis 2021
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Ploemen, Milou (author)
The flash visual evoked potential (FVEP) is an electrical potential recorded with electroencephalogram (EEG) at the occipital cortex. Current FVEP assessment may be elaborated with the acquisition of stimulus response (SR) relation of the visual system. A drawback of this adjustment is the time required for data acquisition. This study aimed to...
master thesis 2021
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Verburgh, Tijmen (author)
This thesis describes the process of selecting different greenhouse gas emission reduction technologies for the application on a redesign of a multi-purpose heavy-lift vessel. Only technologies were considered which did not negatively influence the operability or arrangement of the redesign. The best performing combination of technologies was...
master thesis 2021
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Nijmeijer, Kirsten (author)
The ability to control and adapt joint stiffness is essential in human motor control. Both control loops on the spinal as well as cortical level are likely to play a role in this regulation. However, the cortical mechanisms involved with the online adaptive control of joint stiffness remain largely unresolved. This study aimed at identifying...
master thesis 2020
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Santini, Francesca (author)
Introduction: Pes equinus with increased ankle joint stiffness is a common impairment in stroke and Cerebral Palsy (CP) patients with structural and/or neural deficits of the ankle muscles. Equinus gait is characterized by toe-strike, abnormal ankle plantarflexion and decreased ankle range of motion (ROM). A new ankle-foot orthosis (AFO) with...
master thesis 2020
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de Pont, Mike (author)
The human sensorimotor system can be seen as a complex network in which the brain plays an important role, resulting in a difficult-to-understand relation between proprioceptive stimuli and cortical responses. However, understanding this relationship is of added value for understanding various diseases which cause dysfunctionality. In recent...
master thesis 2020
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Liuzzi, Peppe (author)
Biologically inspired neural networks are a promising approach to understand the causes and improve the treatments of brain damage. Parkinson's disease is a progressive nervous system disorder that affects mainly movements, speech and cognitive problems. It symptoms cannot be cured, though medications can significantly improve the condition....
master thesis 2020
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Dekker, Melina (author)
Freezing of Gait (FoG) is a debilitating walking problem affecting over 50\% of Parkinson's Disease (PD) patients. Rhythmic cues during FoG can help patients to resume walking. FoG can be detected from lower limb acceleration data, but current detection algorithms lack context, resulting in false positive detection and initiation of cues when...
master thesis 2020
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Christoforidis, Christos (author)
Experimental data were obtained from riding a steer-by-wire bicycle on the open road while perturbing balance with impulsive forces at the seat post (lateral pertubations) as well as perturbing balance with impulsive torques at the steering assembly (steering pertubations). The experiments were conducted at 2.6–5.6 m/s covering both the stable...
master thesis 2019
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van Beurden, Anouk (author)
Dravet Syndrome is a rare epileptic disorder, which is caused in more than 70% of all patients by a loss-of-function mutation in the SCN1A gene encoding sodium channel Nav1.1. One of the main problems for treatment of patients with Dravet Syndrome is drug resistance and there are no biomarkers to monitor the efficacy of a particular treatment....
master thesis 2019
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van Adrichem, Bram (author)
Humans continuously adapt to new sensorimotor environments, wherein we create motor commands to execute movements properly, such as picking up the telephone or riding a bike. Generalization of motor commands means that a learned movement, such as grasping a bottle, transfers to similar but new environments, such as grasping a carton of milk....
master thesis 2019
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de Haan, Jelle Waling (author)
The objective of this research is to identify the passive response of the rider’s body to translational and rotational random perturbations. A custom made bicycle mock-up equipped with a system of sensors has been developed, capable of measuring the linear accelerations, angular velocity and the rider’s force responses in all translational axes...
master thesis 2019
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