Estimation of multiple components and parameters for quantitative MRI

Magnetic Resonance Imaging (MRI) is a flexible medical imaging technique that facilitates measurement of a wide range of contrasts particularly in soft tissue (e.g. brain and heart). Conventionally, qualitative images are acquired in which certain physical tissue properties are emphasized such as the transverse and longitudinal relaxation times....

Methods for Multi-Parametric Quantitative MRI

Magnetic resonance imaging (MRI) is the primary modality for the imaging of soft tissues (e.g. brain, muscle, liver). Therefore, it is an essential radiological tool for diagnosis and surgical planning. The contrast in MR images is due to tissues responding differently to the magnetic fields generated by the scan-ning system. This response can...

Image analysis methods for dynamic hepatocyte-specific contrast enhanced MRI

Patients with colorectal cancer are frequently presented with liver metastases for which (partial) resection is often the best therapy. However, the future remnant liver, the remaining part of the liver after resection, should allow adequate liver function to avoid liver failure. This thesis presents novel methods for the accurate voxel-wise...