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van Duijnhoven, Hugo (author)
master thesis 2023
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Smedema, Jette (author)
<b>Background</b><br/>Adolescent idiopathic scoliosis (AIS) with a Cobb angle larger than 45° is a spinal deformity that needs surgical treatment to stop progression and reduce pain. Spinal fusion is a surgical procedure where rods are attached to the spine through screws to diminish the Cobb angle.<br/><b>Objective</b><br/>The metal rods are...
master thesis 2022
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Willemse, Kirsten (author)
The incidence of osteoporotic vertebral compression fractures (VCFs) is rapidly increasing, necessitating the identification of the most appropriate treatment method. The well-established first and second generation surgical procedures are not capable of giving optimal outcomes. Moreover, my literature study has shown little to no improvements...
master thesis 2020
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Magré, Joëll (author)
The management of large acetabular defects remains one of the most challenging aspects of revision total hip arthroplasties. Failure of frequently used acetabular reconstruction components are, among others, caused by the lack of biological fixation, a non-physiological stress distribution and stress-shielding. Attempting to diminish these...
master thesis 2020
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Zeringa, Eva (author)
The synergy of hydrogel processing and 3D printing technologies has paved the way for the development of advanced tissue engineering scaffolds. Hydrogels constitute a promising class of materials for the creation of scaffolds due to their permeable environment, suitable for encapsulation, as well as their tunable chemical and mechanical properties...
master thesis 2020
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Dijkmans, Floor (author)
Prosthetic failure due to implant-associated infections remains a big problem, despite the extensive use of implants and number of researches performed on this topic. A new problem arises with the development of additively manufactured complex orthopedic metal implants. In spite of the advantages that come with patient specific implants to cure...
master thesis 2019
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de Jong, Yoni (author)
Introduction. To prevent burns from scar formation and contraction, the use of splinting therapy in the early phase of wound healing is considered as an effective non-surgical method. Splinting entails the application of a mechanical load in the opposite direction of the contractile force within the wound, based on the assumption that wound- or...
master thesis 2019
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Wermink, Suzanne (author)
Adolescent idiopathic scoliosis (AIS) is a three-dimensional deformity of the spine that can be treated by wearing a correctional rigid brace. The goal of brace treatment is prevention of curve progression, and in some cases the curve even decreases. The current problem concerning treatment of AIS lays in the design decisions made during...
master thesis 2019
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Smit, Stefan (author)
Osteogenesis imperfecta (OI), also known as brittle bone disease, affects 1 in 10.000 births. This disease is characterized by skeletal dysplasias, bone fragility and many secondary health issues. It is a heritable disorder affecting collagen type I, which is an essential protein in bone tissue. Post-translational overmodifications in collagen...
master thesis 2018
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van Dongen, Isabelle (author)
The fundamentals of the nanopatterned surface can be found on the wings of cicada. These bactericidal surfaces are artificially mimicked on the surface of the implant to reduce the infection rate, which is one of the main complication after joint replacement. The bactericidal properties of the nanopatterned surface are a promising feature....
master thesis 2017
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Kuiper, R.J.A. (author)
Scoliosis is a three-dimensional deformity of the spine most prevalent in adolescent females. As the etiology is often unknown, treatment focusses on preventing curve progression and ranges from observation for mild cases to brace treatment and eventually surgery for the worst cases. This report consists of three different studies, which are...
master thesis 2017
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Bakhshandeh, S. (author)
master thesis 2016
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Abinzano, F. (author)
Osteoarthritis is a degenerative disease of the joints that reduces physical function and leads to chronic pain. It occurs mostly in persons from an age of 50 years of older and can be considered a disease of the aging population. Although there is no clear evidence of its effects, induced hyperthermia is sometimes prescribed to these patients...
master thesis 2016
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Karthik Raman, H. (author)
Chondrocyte is the only cell type which constitutes the articular cartilage, is solely responsible for the turnover of extracellular matrix composed of proteoglycans, type II collagen and water. Chondrocytes experience a unique ionic/osmotic environment, which is attributable to the polyanionic proteoglycan, which carry a high fixed negative...
master thesis 2016
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Villamar Jorgge, J.A. (author)
In the present study, the effect of concentration, osmolality and charge of x-ray contrast agents on their diffusion and equilibrium distribution across different zones of cartilage was investigated. Full-thickness cartilage discs (Ø = 8.5 mm, n = 3) were extracted from healthy equine femoral condyle (n = 2). The diffusion of four different...
master thesis 2014
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Glynou, A. (author)
The present project focused on the design and development of a mechanical loading device that allows the convection studies in cartilage within a micro-CT chamber. A plastic-made device was designed and build in order to ensure the successful operation in the micro-CT. Besides that it allowed the monitoring of the tissue material properties by...
master thesis 2014
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Sanchez, P.F. (author)
The tendon is the connective tissues that attach the muscles to bones. It plays an important role in the mechanics of the articulation because the tendon transmits the tensile force from the muscle to the correspondent bone. Even though the tendons are designed to support different loading conditions, it generally accepted that mechanical...
master thesis 2013
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Rauker, J. (author)
Nanoindentation using AFM and nanoindeter was used to measure the Young's modulus of 20LP10L20-LLA40 Microspheres and Gelatin-Methacrylamide (Gelma). Three different analytical methods were used for calculating the Young's modulus of microspheres in order to compare the results and find the optimal analytical method. The Young's modulus of GelMA...
master thesis 2013
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Roels, P.L. (author)
Cam impingement appears to be an important factor in the development of early osteoarthritis (OA) of the hip. A Cam is generally diagnosed in young and active adults, already at the age of thirteen. Therefore, it has been suggested that excessive femoral loading during skeletal development might trigger the abnormal morphology. The goal of this...
master thesis 2013
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Reyes Lua, A.M. (author)
The elastic strain limit of the tendon appears to be an omnipresent parameter in the literature in many of the problems described related to its pathologic conditions, which are often related to the repetitive loading tendons undergo during life. In other words, the study of the fatigue resistance of the tendons may provide information about the...
master thesis 2012
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