Searched for: contributor%3A%22Zadpoor%2C+A.A.+%28graduation+committee%29%22
(1 - 20 of 39)

Pages

document
van de Gevel, Sophie (author)
Liver transplantation remains the only definite cure for end-stage liver disease, yet the demand for donor livers far surpasses their supply, resulting in substantial wait-list mortality rates. This has led to the exploration of extended criteria donor (ECD) livers, which often exhibit compromised function and susceptibility to post...
master thesis 2023
document
Achten, Huib (author)
Data that can be collected with the use of instrumented implants can help in diagnosis and treatment of complications during the lifetime of total joint replacements. They can give an accurate reading of the status of the implant from within the body. In this research project an electronic system is designed to<br/>feed sensors with enough...
master thesis 2023
document
Schilder, Amaya (author)
Due to the limited availability of suitable livers for transplantation and the increasing use of suboptimal donor livers, which are more prone to ischemia-reperfusion injury (IRI), there is an urgent need for novel graft-ameliorating therapies. The promising capacities of (liver-derived) mesenchymal stromal cells ((L-)MSC) in mitigating IRI and...
master thesis 2023
document
Guarnotta, Flora (author)
Liver diseases account for two million deaths worldwide each year, and current treatments are limited. 3D bioprinting is a promising technology, that has recently been investigated to tackle this challenge. However, the cells and hydrogels used for bioprinting are not human-derived and do not replicate the natural <i>in vivo</i> environment. The...
master thesis 2023
document
Moolenaar, Jet (author)
Introduction: Tibial fracture healing complications occur frequently with reported non-union rates up to 23%. Preoperative patient-specific finite element (FE) modelling of fracture fixation may help to minimize these complications. However, developing such models requires labour-intensive work including (manual) segmentation of bones from...
master thesis 2023
document
Vledder, Amária (author)
Delayed healing or non-union of bone fractures are still clinically and economically relevant problems. Bone healing includes pro- and anti-inflammatory phases, which proved crucial for successful healing. Being able to modulate these inflammatory responses could potentially promote bone fracture healing. Dendritic cells play important roles in...
master thesis 2022
document
Fokker, Marike (author)
Bone defects are a common problem in healthcare today. When the damage is too extensive, the human body is not able to heal itself. Different solutions are available, but they all have limitations. Therefore, the search for a solution to overcome these limitations is important. In this theses a way to create a scaffold out of seperate crumpled...
master thesis 2022
document
Wu, Chu-Hsuan (author)
Nature has always had randomness in many ways. Natural cellular structures, specifically, have used randomized microarchitectures to form mechanically efficient materials, such as wood, sponge, and trabecular bone. Mechanical metamaterials are a class of artificial microarchitected materials designed to carry tensions and compressions with...
master thesis 2022
document
van Houten, Paul (author)
The distribution of multiple materials within a single structure is a strategy that various biological systems rely on to achieve outstanding mechanical performances. These biological examples illustrate the effective utilization of hard rigid and soft flexible materials in particular. The proper composition of such hard-soft materials exceeds...
master thesis 2021
document
Veeger, Robin (author)
Functional gradients in hard-soft interfaces are abundant in nature, and we often mimic them to create strong and tough composites. A powerful tool for the designs and fabrication of biomimetic composites is voxel-based multi-material 3D printing. Earlier researches mainly focused on using this technique in the creation of gradients based on...
master thesis 2021
document
Garmendia Urdalleta, Amaia (author)
Background: Despite the considerable development of the field of orthopedic implants in the past century, complications including poor bone ingrowth and implant associated infection (IAI) persist to this day, causing a huge burden to millions of patients and the healthcare systems worldwide. Additive manufacturing (AM) and the subsequent surface...
master thesis 2021
document
van Dis, Daniëlle (author)
Purpose: Patients with tracheal lesions that exceed half of the trachea’s total length require a tracheal substitute. Tissue engineering, using either synthetic materials or decellularized tracheal tissue, opens up new possibilities for generating tracheal substitutes. Decellularization, a procedure in which the tissue's...
master thesis 2021
document
Eijkel, Dirk (author)
In the last two decades, it has been generally accepted that the interaction between bone and immune cells is critical in the process of bone healing and regeneration. Steering this immune response with the development of biomaterials could lead to implant acceptance in the long term. The understanding of osteoimmunological responses is of high...
master thesis 2021
document
van den Brekel, Thomas (author)
Currently, cardiovascular diseases are the leading cause of death worldwide, and a global ageing population ensures increasing numbers for the foreseeable future. Atherosclerosis, responsible for 80\% of cardiovascular deaths, is nowadays treated with stents, which scaffold the balloon-dilated artery and seals the dissection flaps. In 2016, the...
master thesis 2021
document
Nguyen, Huyen My (author)
Cholangiocarcinoma (CCA) is a highly aggressive biliary tumor with a poor prognosis and limited treatment options. Various critical aspects of CCA development remain unclear. Lately, the dynamic process of epithelial-mesenchymal transition (EMT) was highlighted to play a crucial role in the fundamental mechanism of metastatic dissemination....
master thesis 2021
document
Popa, Bogdan (author)
Objectives: With an increasing life expectancy in the western societies and more people practising extreme sports, the demand for orthopaedic implants is set to increase. Orthopaedic implant loosening is one of the main causes of revision surgeries, leading to increases in the costs of patient care and patient dissatisfaction. Better...
master thesis 2020
document
Šalandová, Monika (author)
Introduction: Aseptic loosening of an orthopaedic implant due to the unsatisfactory attachment to the bone remains one of the most common reasons for failure of these implants. One of the possible approaches for improving the connection between the implanted biomaterial and the bone tissue being formed is the incorporation of bioactive agents...
master thesis 2020
document
Tziotziou, Aikaterini (author)
Atherosclerosis is a prevalent cardiovascular disease and defined as plaque formation inside the arterial intima layer. The atherosclerotic plaque is characterized as anisotropic, soft tissue and a potential plaque rupture could result in life-threatening clinical events, such as ischemic attack or stroke. The plaque rupture mechanism is still...
master thesis 2020
document
Gkoni, Joanna (author)
The high frequency of osteoarthritis in those aged above 60 years combined with the observing trend of overpopulation leads to increased healthcare costs. To date, clinical treatments seem to be insufficient to restore cartilage and underlying bone degeneration. Bioprinting fabrication techniques constitute a promising approach to mimic and...
master thesis 2020
document
Dimaraki, Angeliki (author)
The use of allografts for the treatment of critical size cartilage defects holds disadvantages including the limited number of donors and the compromised chondrocyte viability. These limitations have prompted researchers to explore different options, such as cartilage engineering. Bioprinting, a promising tissue engineering technique, could be...
master thesis 2020
Searched for: contributor%3A%22Zadpoor%2C+A.A.+%28graduation+committee%29%22
(1 - 20 of 39)

Pages