Analysis and engineering of acetyl-CoA metabolism in Saccharomyces cerevisiae

CRISPR/Cas9 is a novel Swiss Army Knife in the field of synthetic biology. The thesis of Harmen van Rossum (Biotechnology/TNW) shows that this tool enables rapid genetic modification of baker’s yeast; six genetic changes could be introduced within one week – previously this could easily take a few months.<br/>The goal of the PhD project was to...