Correlation between the Mechanical Properties and the Structure of the Equine Osteochondral Interface During Maturation

The osteochondral interface is known to smoothly mitigate the stress concentration over the surface area of the subchondral bone, with a structural transition from the cartilage to bone. These sites in the body are exposed to high forces, which makes them prone to failure. To improve the repair strategies, a better understanding of the...

The effect of material properties on cartilage-like tissue formation: Towards the development of smart biomaterials for cartilage regeneration

Articular cartilage is an avascular tissue type with very limited self-repair capacity, making it prone to degenerative diseases such as osteoarthritis (OA). The current therapeutic strategy for OA patients is predominantly directed towards pain relief rather than preventing degeneration and promoting the regeneration of cartilage tissue....