Searched for: department:"Biomechanical%5C%2BEngineering"
(1 - 8 of 8)
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Janbaz, S. (author), Weinans, H. (author), Zadpoor, A.A. (author)
Recent research has shown the potential of rationally designed geometrical features for controlling the functionality of advanced materials. Of particular recent interest has been the use of geometry for controlling the buckling behaviour of soft materials under compression. However, the effects of geometry may be mixed with those of the...
journal article 2016
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Ahmadi, S.M. (author), Yavari, S.A. (author), Wauthle, R. (author), Pouran, B. (author), Schrooten, J. (author), Weinans, H. (author), Zadpoor, A.A. (author)
It is known that the mechanical properties of bone-mimicking porous biomaterials are a function of the morphological properties of the porous structure, including the configuration and size of the repeating unit cell from which they are made. However, the literature on this topic is limited, primarily because of the challenge in fabricating...
journal article 2015
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Van der Stok, J. (author), Koolen, M.K.E. (author), De Maat, M.P.M. (author), Amin Yavari, S. (author), Alblas, J. (author), Patka, P. (author), Verhaar, J.A.N. (author), Van Lieshout, E.E.M. (author), Zadpoor, A.A. (author), Weinans, H.H. (author), Jahr, H. (author)
Regeneration of load-bearing segmental bone defects is a major challenge in trauma and orthopaedic surgery. The ideal bone graft substitute is a biomaterial that provides immediate mechanical stability, while stimulating bone regeneration to completely bridge defects over a short period. Therefore, selective laser melted porous titanium,...
journal article 2015
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Siebelt, M. (author), Groen, H.C. (author), Koelewijn, S.J. (author), De Blois, E. (author), Sandker, M. (author), Waarsing, J.H. (author), Müller, C. (author), Van Osch, G.J.V.M. (author), De Jong, M. (author), Weinans, H.H. (author)
Introduction Articular cartilage needs sulfated-glycosaminoglycans (sGAGs) to withstand high pressures while mechanically loaded. Chondrocyte sGAG synthesis is regulated by exposure to compressive forces. Moderate physical exercise is known to improve cartilage sGAG content and might protect against osteoarthritis (OA). This study investigated...
journal article 2014
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Van Tiel, J. (author), Reijman, M. (author), Bos, P.K. (author), Hermans, J. (author), Van Buul, G.M. (author), Bron, E.E. (author), Klein, S. (author), Verhaar, J.A.N. (author), Krestin, G.P. (author), Bierma-Zeinstra, S.M.A. (author), Weinans, H. (author), Kotek, G. (author), Oei, E.H.G. (author)
journal article 2013
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Poldervaart, M.T. (author), Wang, H. (author), Van der Stok, J. (author), Weinans, H.H. (author), Leeuwenburgh, S.C.G. (author), Cumhur Öner, F. (author), Dhert, W.J.A. (author), Alblas, J. (author)
The design of bioactive three-dimensional (3D) scaffolds is a major focus in bone tissue engineering. Incorporation of growth factors into bioprinted scaffolds offers many new possibilities regarding both biological and architectural properties of the scaffolds. This study investigates whether the sustained release of bone morphogenetic protein...
journal article 2013
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Van der Stok, J. (author), Wang, H. (author), Yavari, S.A. (author), Siebelt, M. (author), Sandker, M. (author), Waarsing, J.H. (author), Verhaar, J.A.N. (author), Jahr, H. (author), Zadpoor, A.A. (author), Leeuwenburgh, S.C.G. (author), Weinans, H. (author)
Porous titanium scaffolds are a promising class of biomaterials for grafting large bone defects, because titanium provides sufficient mechanical support, whereas its porous structure allows bone ingrowth resulting in good osseointegration. To reinforce porous titanium scaffolds with biological cues that enhance and continue bone regeneration,...
journal article 2013
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Van Buul, G. (author), Kotek, G. (author), Wielopolski, P.A. (author), Farrell, E. (author), Bos, P.K. (author), Weinans, H. (author), Grohnert, A.U. (author), Jahr, H. (author), Verhaar, J.A.N. (author), Krestin, G.P. (author), Van Osch, G.J.V.M. (author), Bernsen, M.R. (author)
Background: Articular cartilage has very limited intrinsic regenerative capacity, making cell-based therapy a tempting approach for cartilage repair. Cell tracking can be a major step towards unraveling and improving the repair process of these therapies. We studied superparamagnetic iron oxides (SPIO) for labeling human bone marrow-derived...
journal article 2011
Searched for: department:"Biomechanical%5C%2BEngineering"
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