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The future of artificial intelligence in intensive care: moving from predictive to actionable AI

Smit, J.M. (author), Krijthe, J.H. (author), van Bommel, Jasper (author), van Genderen, M. E. (author), Labrecque, J. A. (author), Komorowski, M. (author), Gommers, D.A.M.P.J. (author), Reinders, M.J.T. (author)

Artificial intelligence (AI) research in the intensive care unit (ICU) mainly focuses on developing models (from linear regression to deep learning) to predict out-<br/>comes, such as mortality or sepsis [1, 2]. However, there is another important aspect of AI that is typically not framed as AI (although it may be more worthy of the name), which...

journal article 2023

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Biomarker identification for endometriosis as a target for real-time intraoperative fluorescent imaging: A new approach using transcriptomic analysis to broaden the search for potential biomarkers

Tummers, Fokkedien H.M.P. (author), Bazelmans, Maria K. (author), Jansen, F.W. (author), Blikkendaal, Mathijs D. (author), Vahrmeijer, Alexander L. (author), Kuppen, P.J.K. (author)

Intra-operative fluorescent imaging of endometriosis could help to optimize surgical treatment. Potential biomarkers to use as target for endometriosis-binding fluorescent probes were identified using a new five-phase transcriptomics-based approach to broaden the search for biomarkers. Using publicly available datasets, a differentially...

review 2023

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Sex differences in characteristics of atrial fibrillation recurrence post surgical pulmonary vein isolation

Veen, Danny (author), Verbeek, Eva C. (author), Kavousi, Maryam (author), Huigen, Jos (author), Mijnen-Schra, Annet (author), Cocchieri, Riccardo (author), Khan, Muchtiar (author), de Groot, N.M.S. (author)

Background: Prior studies demonstrated that female sex is associated with arrhythmia recurrence after endovascular pulmonary vein isolation (PVI). However, it is unknown if the sexes differ in outcome after video assisted thoracoscopic (VATS) PVI. The aim of this study was therefore to compare characteristics of recurrent AF episodes in a...

journal article 2023

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Spectroscopic optical coherence tomography at 1200 nm for lipid detection

Kuttippurath, Vivek (author), Slijkhuis, Nuria (author), Liu, Shengnan (author), van Soest, G. (author)

Significance: Spectroscopic analysis of optical coherence tomography (OCT) data can yield added information about the sample's chemical composition, along with high-resolution images. Typical commercial OCT systems operate at wavelengths that may not be optimal for identifying lipid-containing samples based on absorption features. Aim: The...

journal article 2023

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Ankle-Foot-Orthosis “Hermes” Compensates Pathological Ankle Stiffness of Chronic Stroke—A Proof of Concept

Rodriguez Hernandez, K.E. (author), de Groot, J.H. (author), Baas, Frank (author), Stijntjes, M. (author), Grootendorst, E.R.M. (author), Schiemanck, S.K. (author), van der Helm, F.C.T. (author), van der Kooij, H. (author), Mugge, W. (author)

Individuals with an upper motor neuron syndrome, e.g., stroke survivors, may have a pathological increase of passive ankle stiffness due to spasticity, that impairs ankle function and activities such as walking. To improve mobility, walking aids such as ankle-foot orthoses and orthopaedic shoes are prescribed. However, these walking aids...

journal article 2023

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Mild Stroke, Serious Problems: Limitations in Balance and Gait Capacity and the Impact on Fall Rate, and Physical Activity

Roelofs, Jolanda M.B. (author), Zandvliet, Sarah B. (author), Schut, I.M. (author), Huisinga, Anouk C.M. (author), Schouten, A.C. (author), Hendricks, Henk T. (author), de Kam, Digna (author), Aerden, Leo A.M. (author), Bussmann, J.B.J. (author), Geurts, Alexander C.H. (author), Weerdesteyn, Vivian (author)

Background: After mild stroke persistent balance limitations may occur, creating a risk factor for fear of falling, falls, and reduced activity levels. Objective. To investigate whether individuals in the chronic phase after mild stroke show balance and gait limitations, elevated fall risk, reduced balance confidence, and physical activity...

journal article 2023

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Magnitude and variability of individual elbow load in repetitive baseball pitching

van Trigt, B. (author), van Hogerwou, Thomas (author), Leenen, A.J.R. (author), Hoozemans, Marco J.M. (author), van der Helm, F.C.T. (author), Veeger, H.E.J. (author)

In baseball pitchers the elbow is exposed to high and repetitive loads (i.e. external valgus torque), caused by pitching a high number of balls in a practice session or game. This can result in overuse injuries like the ulnar collateral ligament (UCL) injury. To understand injury mechanisms, the effect of repetitive pitching on the elbow load...

journal article 2023

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The relevance of reducing Veress needle overshooting

Horeman, T. (author), Postema, R.R. (author), Fischer, T. (author), Calleja-Agius, J. (author), Camenzuli, C. (author), Alvino, L. (author), Hardon, S.F. (author), Bonjer, H. J. (author)

Safe insertion of the Veress needle during laparoscopy relies on the surgeons’ technical skills in order to stop needle insertion just in time to prevent overshooting in the underlying organs. To reduce this risk, a wide variety of Veress needle systems were developed with safety mechanisms that limit the insertion speed, insertion depth or...

journal article 2023

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Critical appraisal of technologies to assess electrical activity during atrial fibrillation: a position paper from the European Heart Rhythm Association and European Society of Cardiology Working Group on eCardiology in collaboration with the Heart Rhythm Society, Asia Pacific Heart Rhythm Society, Latin American Heart Rhythm Society and Computing in Cardiology

de Groot, N.M.S. (author), Shah, Dipen (author), Boyle, Patrick M. (author), Anter, Elad (author), Clifford, Gari D. (author), Deisenhofer, Isabel (author), van Dessel, Pascal (author), Dilaveris, Polychronis (author), van der Veen, A.J. (author)

We aim to provide a critical appraisal of basic concepts underlying signal recording and processing technologies applied for (i) atrial fibrillation (AF) mapping to unravel AF mechanisms and/or identifying target sites for AF therapy and (ii) AF detection, to optimize usage of technologies, stimulate research aimed at closing knowledge gaps,...

journal article 2022

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Feasibility of a home-based physiotherapy intervention to promote post-stroke mobility: A randomized controlled pilot study

Jarbandhan, Ameerani (author), Toelsie, Jerry (author), Veeger, H.E.J. (author), Bipat, Robbert (author), Vanhees, Luc (author), Buys, Roselien (author)

Objectives Home-based physiotherapy interventions to improve post-stroke mobility are successful in high-income countries. These programs require less resources compared to center-based programs. However, feasibility of such an intervention in a low and middle-income setting remains unknown. Therefore, the SunRISe (Stroke Rehabilitation In...

journal article 2022

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Surface Electrocardiogram Reconstruction Using Intra-operative Electrograms

Moghaddasi, Hanie (author), Hunyadi, Borbala (author), van der Veen, A.J. (author), de Groot, N.M.S. (author), Hendriks, R.C. (author)

Atrial Fibrillation (AF) is the most sustained arrhythmia in the heart. On the surface electrocardiogram (ECG), AF is characterised by the irregular RR intervals and by fibrillatory waves or the absence of a P wave. Since AF is a progressive disease, timely and correct detection is crucial for AF treatment. Detailed insight into the areas of...

conference paper 2022

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Quantifying Within-Individual Elbow Load Variability in Youth Elite Baseball Pitchers and Its Role in Overuse Injuries

van Trigt, B. (author), Bouman, F.F. (author), Leenen, Antonius J. R. (author), Hoozemans, Marco J.M. (author), van der Helm, F.C.T. (author), Veeger, H.E.J. (author)

Medial elbow overuse injuries are rising in baseball. The external valgus torque magnitude is a possible risk factor for medial elbow injuries. The magnitude on its own cannot explain why one pitcher sustains an injury and another does not. Therefore, the aim of this study is to describe the within-individual external valgus torque variability...

journal article 2022

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Shoulder muscle activity after latissimus dorsi transfer in an active elevation

Gurnani, Navin (author), van Deurzen, Derek F.P. (author), Willems, W. Jaap (author), Janssen, Thomas W.J. (author), Veeger, H.E.J. (author)

Background: After latissimus dorsi transfer (LDT), an increase in scapulothoracic (ST) contribution in thoracohumeral (TH) elevation is observed when compared to the asymptomatic shoulder. It is not known which shoulder muscles contribute to this change in shoulder kinematics, and whether the timing of muscle recruitment has altered after LDT...

journal article 2022

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Energy flow through the lower extremities in high school baseball pitching

de Swart, A.F.M.J. (author), van Trigt, B. (author), Wasserberger, Kyle (author), Hoozemans, Marco J.M. (author), Veeger, H.E.J. (author), Oliver, Gretchen D. (author)

It is generally accepted that most of the energy transferred to the ball during a baseball pitch is generated in the trunk and lower extremities. Therefore, purpose of this study was to assess the energy flow through the lower extremities during a baseball pitch. It was hypothesised that the (stabilising) leading leg mainly transfers energy...

journal article 2022

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Using Wearable Sensors to Estimate Mechanical Power Output in Cyclical Sports Other than Cycling: A Review

De Vette, V.G. (author), Veeger, H.E.J. (author), van Dijk, M.P. (author)

More insight into in-field mechanical power in cyclical sports is useful for coaches, sport scientists, and athletes for various reasons. To estimate in-field mechanical power, the use of wearable sensors can be a convenient solution. However, as many model options and approaches for mechanical power estimation using wearable sensors exist, and...

review 2022

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Unperceived motor actions of the balance system interfere with the causal attribution of self-motion

Tisserand, Romain (author), Rasman, Brandon G. (author), Omerovic, Nina (author), Peters, Ryan M. (author), Forbes, P.A. (author), Blouin, Jean Sébastien (author)

The instability of human bipedalism demands that the brain accurately senses balancing self-motion and determines whether movements originate from self-generated actions or external disturbances. Here, we challenge the longstanding notion that this process relies on a single representation of the body and world to accurately perceive postural...

journal article 2022

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Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro and in vivo biofilm

de Vor, Lisanne (author), van Dijk, Bruce (author), van Kessel, Kok (author), Kavanaugh, Jeffrey S. (author), de Haas, Carla (author), Aerts, Piet C. (author), Ramakers, R.M. (author), Beekman, F.J. (author), Weinans, Harrie (author)

Implant-associated Staphylococcus aureus infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. Monoclonal antibodies (mAbs) could provide an alternative approach to improve the diagnosis and potential treatment of biofilm-related infections. Here, we show...

journal article 2022

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Obtaining wheelchair kinematics with one sensor only? The trade-off between number of inertial sensors and accuracy for measuring wheelchair mobility performance in sports

van Dijk, M.P. (author), van der Slikke, R.M.A. (author), Rupf, Rob (author), Hoozemans, Marco J.M. (author), Berger, Monique A.M. (author), Veeger, H.E.J. (author)

In wheelchair sports, the use of Inertial Measurement Units (IMUs) has proven to be one of the most accessible ways for ambulatory measurement of wheelchair kinematics. A three-IMU configuration, with one IMU attached to the wheelchair frame and two IMUs on each wheel axle, has previously shown accurate results and is considered optimal for...

journal article 2022

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Fastball pitching performance only slightly decreases after mobility impediment of the pelvis and trunk—Do (catch-up) compensation strategies come into play?

Leenen, A.J.R. (author), van Trigt, B. (author), Hoozemans, M. J.M. (author), Veeger, H.E.J. (author)

Background: Baseball pitching performance can be mechanically explained by the summation of speed principle and the principle of optimal coordination of partial momenta. Impeding optimal energy generation or transfer by or between the pelvis and trunk segments could provide valuable insight into possible compensation or catch-up mechanisms...

journal article 2022

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The effect of an occlusion-induced delay on braking behavior in critical situations: A driving simulator study

de Winter, J.C.F. (author), Saffarian, M (author), Senders, John W. (author)

Objective: To share results of an experiment that used visual occlusion for a new purpose: inducing a waiting time. Background: Senders was a leading figure in human factors. In his research on the visual demands of driving, he used occlusion techniques. Methods: In a simulator experiment, we examined how drivers brake for different levels of...

journal article 2022