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Fleres, Antonio (author), Veling, Louise (author), Broz, F. (author), Damiano, Luisa (author)This article proposes an integrative approach to robotics research, based on bringing interdisciplinarity into the lab. Such an approach will facilitate researchers across various fields in gaining a more nuanced understanding of technology, how it is developed, and its potential impacts. We describe how a philosopher spent time embedded in...journal article 2023
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Fleres, Antonio (author), Veling, Louise (author), Broz, F. (author), Damiano, Luisa (author)In the original publication of this article, the affiliation information of two authors was inadvertently published incorrectly. Please find the correct affiliation information below: Antonio Fleres 1PhD School for Communication Studies, IULM University, via Carlo Bo 1, 20143 Milan, Italy Luisa Damiano 4Department of Communication, Arts and...journal article 2023
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Zhang, M. (author), Bouland, G.A. (author), Holstege, H. (author), Reinders, M.J.T. (author)Background and Objectives - With age, somatic mutations accumulated in human brain cells can lead to various neurologic disorders and brain tumors. Because the incidence rate of Alzheimer disease (AD) increases exponentially with age, investigating the association between AD and the accumulation of somatic mutation can help understand the...journal article 2023
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Baker, Emily (author), Leonenko, Ganna (author), Schmidt, Karl Michael (author), Hill, Matthew (author), Myers, Amanda J. (author), Shoai, Maryam (author), de Rojas, Itziar (author), Tesi, N. (author), Holstege, H. (author)Introduction Both late-onset Alzheimer’s disease (AD) and ageing have a strong genetic component. In each case, many associated variants have been discovered, but how much missing heritability remains to be discovered is debated. Variability in the estimation of SNP-based heritability could explain the differences in reported heritability....journal article 2023
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Sharma, Bhawana (author), Sharma, Lokesh (author), Lal, C. (author), Roy, Satyabrata (author)Internet of Things (IoT) applications are growing in popularity for being widely used in many real-world services. In an IoT ecosystem, many devices are connected with each other via internet, making IoT networks more vulnerable to various types of cyber attacks, thus a major concern in its deployment is network security and user privacy. To...journal article 2023
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Zou, L. (author), Zhan, Xiu xiu (author), Sun, Jie (author), Hanjalic, A. (author), Wang, H. (author)Temporal networks refer to networks like physical contact networks whose topology changes over time. Predicting future temporal network is crucial e.g., to forecast the epidemics. Existing prediction methods are either relatively accurate but black-box, or white-box but less accurate. The lack of interpretable and accurate prediction methods...journal article 2022
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Fernández Robledo, O. (author), Zhan, X. (author), Hanjalic, A. (author), Wang, H. (author)Multiple network embedding algorithms have been proposed to perform the prediction of missing or future links in complex networks. However, we lack the understanding of how network topology affects their performance, or which algorithms are more likely to perform better given the topological properties of the network. In this paper, we...journal article 2022
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van Bree, Elisabeth J. (author), Guimarães, Rita L.F.P. (author), Lundberg, Mischa (author), Blujdea, Elena R. (author), Rosenkrantz, Jimi L. (author), White, Fred T.G. (author), Reinders, M.J.T. (author), Holstege, H. (author), Jacobs, Frank M.J. (author)Genome-wide association studies (GWAS) have been highly informative in discovering disease-associated loci but are not designed to capture all structural variations in the human genome. Using long-read sequencing data, we discovered widespread structural variation within SINE-VNTR-Alu (SVA) elements, a class of great ape-specific transposable...journal article 2022
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van der Lee, S.J. (author), De Rojas, I. (author), Holstege, H. (author), Hulsman, M. (author), Reinders, M.J.T. (author), Tesi, N. (author), van Rooij, Jeroen (author), Zhao, Y. (author), Zhang, X. (author)Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage<br/>genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found...journal article 2022
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Mol, Merel O. (author), van der Lee, S.J. (author), Hulsman, M. (author), Pijnenburg, Yolande A.L. (author), Scheltens, Phillip (author), Seelaar, Harro (author), van Swieten, John C. (author), Kaat, Laura Donker (author), Holstege, H. (author), van Rooij, Jeroen G.J. (author)Background: Many families with clinical early-onset Alzheimer’s disease (EOAD) remain genetically unexplained. A combination of genetic factors is not standardly investigated. In addition to monogenic causes, we evaluated the possible polygenic architecture in a large series of families, to assess if genetic testing of familial EOAD could be...journal article 2022
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Holstege, H. (author), Hulsman, M.J. (author), Charbonnier, Camille (author), Grenier-Boley, Banjamin (author), Quenez, Olivier (author), Grozeva, Detelina (author), van Rooij, Jeroen G.J. (author), Reinders, M.J.T. (author), van der Lee, S.J. (author)Alzheimer’s disease (AD), the leading cause of dementia, has an estimated<br/>heritability of approximately 70%1. The genetic component of AD has been mainly assessed using genome-wide association studies, which do not capture the risk contributed by rare variants2. Here, we compared the gene-based burden of rare damaging variants in exome...journal article 2022
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Zhang, Jian (author), Hanjalic, A. (author), Jain, Ramesh (author), Hua, Xiansheng (author), Satoh, Shin'ichi (author), Yao, Yazhou (author), Zeng, Dan (author)This special issue provides a premier forum for researchers in multimedia big data to share challenges and recent advancements in learning from noisy multimedia data. The multimedia age and its proliferation of devices and platforms is fueling exponential data growth. As computational power and deep learning algorithms rapidly evolve, the web...review 2022
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Xu, Xing (author), Lin, Kaiyi (author), Yang, Yang (author), Hanjalic, A. (author), Shen, Heng Tao (author)Recently, generative adversarial network (GAN) has shown its strong ability on modeling data distribution via adversarial learning. Cross-modal GAN, which attempts to utilize the power of GAN to model the cross-modal joint distribution and to learn compatible cross-modal features, is becoming the research hotspot. However, the existing cross...journal article 2022
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Subramanyam, S. (author), Viola, Irene (author), Jansen, Jack (author), Alexiou, Evangelos (author), Hanjalic, A. (author), Cesar, Pablo (author)Technological advances in head-mounted displays and novel real-time 3D acquisition and reconstruction solutions have fostered the development of 6 Degrees of Freedom (6DoF) teleimmersive systems for social VR applications. Point clouds have emerged as a popular format for such applications, owing to their simplicity and versatility; yet,...conference paper 2022
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Das, B. (author), Hanjalic, A. (author), Isufi, E. (author)Data processing over graphs is usually done on graphs of fixed size. However, graphs often grow with new nodes arriving over time. Knowing the connectivity information of these nodes, and thus, the expanded graph is crucial for processing data over the expanded graph. In its absence, its inference and the subsequent data processing become...journal article 2022
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Li, Meng (author), Chen, Yifei (author), Lal, C. (author), Conti, M. (author), Martinelli, Fabio (author), Alazab, Mamoun (author)Security and privacy issues have become a major hindrance to the broad adoption of Ride-Hailing Services (RHSs). In this article, we introduce a new collusion attack initiated by the Ride-Hailing Service Provider (RHSP) and a driver that could easily link the real riders and their anonymous requests (credentials). Besides this attack,...journal article 2022
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Zhang, M. (author), Ganz, Andrea B. (author), Rohde, Susan (author), Rozemuller, Annemieke J.M. (author), Bank, Netherlands Brain (author), Reinders, M.J.T. (author), Scheltens, Philip (author), Hulsman, M. (author), Hoozemans, Jeroen J.M. (author), Holstege, H. (author)Introduction: With increasing age, neuropathological substrates associated with Alzheimer's disease (AD) accumulate in brains of cognitively healthy individuals—are they resilient, or resistant to AD-associated neuropathologies?. Methods: In 85 centenarian brains, we correlated NIA (amyloid) stages, Braak (neurofibrillary tangle) stages, and...journal article 2022
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Li, Roger Zhe (author), Urbano, Julián (author), Hanjalic, A. (author)Direct optimization of IR metrics has often been adopted as an approach to devise and develop ranking-based recommender systems. Most methods following this approach (e.g. TFMAP, CLiMF, Top-N-Rank) aim at optimizing the same metric being used for evaluation, under the assumption that this will lead to the best performance. A number of studies...conference paper 2021
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Urbano, Julián (author), Corsi, M. (author), Hanjalic, A. (author)Statistical significance tests are the main tool that IR practitioners use to determine the reliability of their experimental evaluation results. The question of which test behaves best with IR evaluation data has been around for decades, and has seen all kinds of results and recommendations. Definitive answer to this question has recently...conference paper 2021
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Slokom, M. (author), Hanjalic, A. (author), Larson, M.A. (author)In this paper, we propose a new privacy solution for the data used to train a recommender system, i.e., the user–item matrix. The user–item matrix contains implicit information, which can be inferred using a classifier, leading to potential privacy violations. Our solution, called Personalized Blurring (PerBlur), is a simple, yet effective,...journal article 2021