Searched for: faculty%3A%22Applied%255C%252BSciences%22
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Laan, A.C. (author), Santini, C. (author), Jennings, L. (author), De Jong, M. (author), Bernsen, M.R. (author), Denkova, A.G. (author)
Background Single photon emission computed tomography (SPECT) is an indispensable tool in the determination of the in vivo fate of polymeric micelles. However, for this purpose, the micelles need to be radiolabeled, and almost all radiolabeling procedures published to date involve the conjugation of a chelating agent to the constituting polymer,...
journal article 2016
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Peruzzini, D. (author), Viti, J. (author), Tortoli, P. (author), Verweij, M.D. (author), De Jong, N. (author), Vos, H.J. (author)
Currently, in medical ultrasound contrast agent (UCA) imaging the second harmonic scattering of the microbubbles is regularly used. This scattering is in competition with the signal that is caused by nonlinear wave propagation in tissue. It was reported that UCA imaging based on the third or higher harmonics, i.e. “superharmonic” imaging, shows...
conference paper 2015
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De Jong, M. (author)
Photovoltaic devices are a widely available, long lasting means of generating sustainable energy. Unfortunately, the integration of such devices into society is to date still limited. This is in part due to the much less than optimal efficiency of conversion of sunlight to electricity, but also by the physical limitations of integrating...
doctoral thesis 2015
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Camfferman, F.A. (author), Ecury-Goossen, G.M. (author), La Roche, J.E. (author), De Jong, N. (author), Van 't Leven, W. (author), Vos, H.J. (author), Verweij, M.D. (author), Nasserinejad, K. (author), Cools, F. (author), Govaert, P. (author), Dudink, J. (author)
Introduction: Preterm infants are born during critical stages of brain development, in which the adaptive capacity of the fetus to extra-uterine environment is limited. Inadequate brain perfusion has been directly linked to preterm brain damage. Advanced high-frequency ultrasound probes and processing algorithms allow visualization of...
journal article 2015
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Kruizinga, P. (author), Springeling, G. (author), Van Soest, G. (author), Van der Steen, A.F.W. (author), De Jong, N. (author), Robertus, J.L. (author), Van der Lugt, A. (author)
We introduce a method for photoacoustic imaging of the carotid artery, tailored toward detection of lipid-rich atherosclerotic lesions. A common human carotid artery was obtained at autopsy, embedded in a neck mimicking phantom and imaged with a multimodality imaging system using interstitial illumination. Light was delivered through a 1.25-mm...
journal article 2014
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De Luca, G.M.R. (author), Breedijk, R.M.P. (author), Brandt, R.A.J. (author), Zeelenberg, C.H.C. (author), De Jong, B.E. (author), Timmermans, W. (author), Nahidi Azar, L. (author), Hoebe, R.A. (author), Stallinga, S. (author), Manders, E.M.M. (author)
We present a new super-resolution technique, Re-scan Confocal Microscopy (RCM), based on standard confocal microscopy extended with an optical (re-scanning) unit that projects the image directly on a CCD-camera. This new microscope has improved lateral resolution and strongly improved sensitivity while maintaining the sectioning capability of a...
journal article 2013
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Bol, K. (author), Haeck, J.C. (author), Groen, H.C. (author), Niessen, W.J. (author), Bernsen, M.R. (author), De Jong, M. (author), Veenland, J.F. (author)
Although efficient delivery and distribution of treatment agents over the whole tumor is essential for successful tumor treatment, the distribution of most of these agents cannot be visualized. However, with single-photon emission computed tomography (SPECT), both delivery and uptake of radiolabeled peptides can be visualized in a neuroendocrine...
journal article 2013
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Ten Kate, O.M. (author), De Jong, M. (author), Hintzen, H.T. (author), Van der Kolk, E. (author)
Solar cells of which the efficiency is not limited by the Shockley-Queisser limit can be obtained by integrating a luminescent spectral conversion layer into the cell structure. We have calculated the maximum efficiency of state-of-the-art c-Si, pc-Si, a-Si, CdTe, GaAs, CIS, CIGS, CGS, GaSb, and Ge solar cells with and without an integrated...
journal article 2013
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Bult, W. (author), Kroeze, S.G.C. (author), Elschot, M. (author), Seevinck, P.R. (author), Beekman, F.J. (author), De Jong, H.W.A.M. (author), Uges, D.R.A. (author), Kosterink, J.G.W. (author), Luijten, P.R. (author), Hennink, W.E. (author)
The increasing incidence of small renal tumors in an aging population with comorbidities has stimulated the development of minimally invasive treatments. This study aimed to assess the efficacy and demonstrate feasibility of multimodality imaging of intratumoral administration of holmium-166 microspheres (166HoAcAcMS). This new technique locally...
journal article 2013
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Marciniak, B.C. (author), Pabijaniak, M. (author), De Jong, A. (author), Dühring, R. (author), Seidel, G. (author), Hillen, W. (author), Kuipers, O.P. (author)
Background: In Bacillus subtilis and its relatives carbon catabolite control, a mechanism enabling to reach maximal efficiency of carbon and energy sources metabolism, is achieved by the global regulator CcpA (carbon catabolite protein A). CcpA in a complex with HPr-Ser-P (seryl-phosphorylated form of histidine-containing protein, HPr) binds to...
journal article 2012
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De Jong, A. (author), Pietersma, H. (author), Cordes, M. (author), Kuipers, O.P. (author), Kok, J. (author)
Background: Accurate prediction of DNA motifs that are targets of RNA polymerases, sigma factors and transcription factors (TFs) in prokaryotes is a difficult mission mainly due to as yet undiscovered features in DNA sequences or structures in promoter regions. Improved prediction and comparison algorithms are currently available for identifying...
journal article 2012
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Maresca, D. (author), Jansen, K. (author), Renaud, G. (author), Van Soest, G. (author), Li, X. (author), Zhou, Q. (author), De Jong, N. (author), Shung, K.K. (author), Van der Steen, A.F.W. (author)
We demonstrate the feasibility of intravascular ultrasound (IVUS) chirp imaging as well as chirp reversal ultrasound contrast imaging at intravascular ultrasound frequency. Chirp excitations were emitted with a 34?MHz single crystal intravascular transducer and compared to conventional Gaussian-shaped pulses of equal acoustic pressure. The...
journal article 2012
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Alic, L. (author), Haeck, J.C. (author), Bol, K. (author), Klein, S. (author), Van Tiel, S.T. (author), Wielepolski, P.A. (author), De Jong, M. (author), Niessen, W.J. (author), Bernsen, M. (author), Veenland, J.F. (author)
Background Magnetic resonance imaging (MRI), together with histology, is widely used to diagnose and to monitor treatment in oncology. Spatial correspondence between these modalities provides information about the ability of MRI to characterize cancerous tissue. However, registration is complicated by deformations during pathological processing,...
journal article 2011
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Zhao, Q. (author), Young, I.T. (author), De Jong, J.G.S. (author)
We have constructed a mathematical model to analyze the photon efficiency of frequency-domain fluorescence lifetime imaging microscopy (FLIM). The power of the light source needed for illumination in a FLIM system and the signal-to-noise ratio of the detector have led us to a photon “budget.” These measures are relevant to many fluorescence...
journal article 2011
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Danilouchkine, M.G. (author), Van Neer, P.L.M.J. (author), Matte, G.M. (author), Verwey, M.D. (author), De Jong, N. (author)
Second harmonic imaging is currently adopted as standard in commercial echographic systems. A new imaging technique, coined as superharmonic imaging (SHI), combines the 3rd till the 5th harmonics, arising during nonlinear sound propagation. It could further enhance resolution and quality of echographic images. To meet the bandwidth requirement...
conference paper 2011
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Bol, K. (author), Haeck, J.C. (author), Alic, L. (author), Bernsen, M. (author), De Jong, M. (author), Niessen, W.J. (author), Veenland, J.F. (author)
Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) is becoming an indispensable tool to noninvasively study tumor characteristics. However, many different DCE-analysis methods are currently being used. To compare and validate different methods, histology is the gold standard. For this purpose, exact co-localization between histology...
conference paper 2011
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Van Neer, P. (author), Danilouchkine, M.G. (author), Matte, G. (author), Voormolen, M.M. (author), Verweij, M.D. (author), De Jong, N. (author)
Superharmonic imaging (SHI) targets a combination of the 3rd to 5th harmonics. It was proven to have certain advantages in comparison with the established imaging standards in medical utrasound. SHI enhances the spatial resolution and improves the quality of echographic images, mainly by eliminating reverberation artifacts at the chest wall....
conference paper 2010
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Alic, L. (author), Haeck, J.C. (author), Klein, S. (author), Bol, K. (author), Van Tiel, S.T. (author), Wielepolski, P.A. (author), Bijster, M. (author), Niessen, W.J. (author), Bernsen, M. (author), Veenland, J.F. (author), De Jong, M. (author)
conference paper 2010
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Van Zutphen, T. (author), Baerends, R.J.S. (author), Susanna, K.A. (author), De Jong, A. (author), Kuipers, O.P. (author), Veenhuis, M. (author), Van der Klei, I.J. (author)
Background: Methylotrophic yeast species (e.g. Hansenula polymorpha, Pichia pastoris) can grow on methanol as sole source of carbon and energy. These organisms are important cell factories for the production of recombinant proteins, but are also used in fundamental research as model organisms to study peroxisome biology. During exponential...
journal article 2010
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Vente, M.A.D. (author), De Wit, T.C. (author), Van den Bosch, M.A.A.J. (author), Bult, W. (author), Seevinck, P.R. (author), Zonnenberg, B.A. (author), De Jong, H.W.A.M. (author), Krijger, G.C. (author), Bakker, C.J.G. (author), Van Het Schip, A.D. (author), Nijsen, J.F.W. (author)
journal article 2009
Searched for: faculty%3A%22Applied%255C%252BSciences%22
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