Foot Progression Angle Estimation: An Algorithm for Foot-based Single-Sensor Application

Background: Knee Osteoarthritis (KOA) is the predominant form of osteoarthritis, and its incidence is anticipated to rise due to an ageing and increasingly overweight population. Altering the Foot Progression Angle (FPA) has demonstrated potential in mitigating the progression of KOA. Wearable feedback methods, especially those utilising single...

Co-Culture of Precision-Cut Liver Slices and Liver-Derived Mesenchymal Stromal Cells: An ex vivo model for mesenchymal stromal cell administration during hypothermic oxygenated machine perfusion of the liver

Due to the limited availability of suitable livers for transplantation and the increasing use of suboptimal donor livers, which are more prone to ischemia-reperfusion injury (IRI), there is an urgent need for novel graft-ameliorating therapies. The promising capacities of (liver-derived) mesenchymal stromal cells ((L-)MSC) in mitigating IRI and...

Using the Recovery Phase in Wheelchair Racing to Estimate the Resistance Forces

Insight into in-field mechanical power estimation in wheelchair racing is useful for athletes and coaches. A non-invasive method to estimate mechanical power is by using inertial measurement units (IMUs) to estimate the power lost to resistive forces during wheelchair propulsion. During the recovery phase, no propulsive force acts on the athlete...

Investigating the Theoretical Feasibility of Longitudinal Motion Control in Indoor Cycling Trainers

As the indoor cycling trainer industry keeps innovating, a cycling trainer that has a similar longitudinal motion to outdoor cycling does not yet exist. Therefore, this thesis aimed to design a simulator controller that can actively simulate longitudinal cycling motion and assess its performance in translating outdoor longitudinal cycling...

How Muscle Stiffness affects Neural Control Parameters: Short-Range Stiffness Improves Stability and Feedback Robustness of Musculoskeletal Models

This paper investigates the effect of intrinsic muscle stiffness on neural control parameters in biological musculoskeletal control of stabilisation or reaching tasks. Current model implementations of intrinsic muscle properties are highly simplified, limiting their accuracy in replicating experimental short-range stiffness (SRS) behaviour,...