Searched for: mods_note_programme_s%3A%22Technical%255C+Medicine%255C+%257C%255C+Sensing%255C+and%255C+Stimulation%22
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Kolthof, Roos (author)
<b>Background</b><br/>Spasticity is a condition that affects patients who have sustained an upper motor neuron lesion. Such lesions include for example cerebral palsy (CP), of which 35% is affected by spasticity, and stroke, of which 90% is affected by spasticity. Pharmacological therapy often involves the prescription of oral baclofen. However,...
master thesis 2024
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Leenen, Femke (author)
Introduction <br/>Opioids are vital for pain management but are highly addictive and may lead to opioid-induced respiratory depression (OIRD), which is the primary cause of death related to both prescription and illicit opioid use. This study employed unsupervised machine learning (ML) to examine potential changes in cluster patterns post-opioid...
master thesis 2024
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de Bie, Melissa (author)
Introduction<br/>Patient-ventilator asynchrony (PVA) poses a significant challenge in the management of mechanically ventilated patients, contributing to adverse clinical outcomes. Current methods of detecting PVA rely on visual assessment by clinicians, leading to subjectivity and inconsistency. Therefore, there is a need for automated...
master thesis 2024
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Raaijmakers, Gini (author)
Background: Postoperative junctional ectopic tachycardia (JET) is an arrhythmia associated with increased morbidity and mortality rates in children with congenital heart disease. Developing an automated detection algorithm could aid in early identification and timely treatment of JET.<br/><br/>Methods: A retrospective study was conducted using...
master thesis 2024
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Themans, Tamir (author)
Background context: Intraoperative neuromonitoring (IONM) has proven effective in reducing postoperative neurological complications. However, current understanding of IONM is limited and its precise meaning in relation to neurological outcomes remains unclear. Machine learning (ML) is a promising solution to analyze the excessive amount of IONM...
master thesis 2024
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Francovich, Juliette (author)
Many patients in the intensive care unit (ICU) depend on mechanical ventilation due to conditions such as severe lung disease, traumatic brain injury, or postoperative coma. While mechanical ventilation is a potentially life-saving intervention, it also has harmful side effects. Especially in patients with lung disease, such as the acute...
master thesis 2024
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Oerlemans, Carlijn (author)
Study objectives: Conventional sleep scoring is based on the scoring criteria of the American Association of Sleep Medicine (AASM) but may not be suited to describe sleep in critically ill children admitted to the Pediatric Intensive Care Unit (PICU). In this study, an anomaly detection model using Gaussian Models trained on sleep stages in data...
master thesis 2024
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van Marrewijk, Esther (author)
Introduction<br/>Reverberation causes a reduced speech perception in cochlear implant (CI) users. Therefore, a dereverberation method was proposed based on the weighted prediction error (WPE) algorithm with input from a deep neural network. The speech intelligibility for normal and hearing-aided listeners is improved by cancelling the late...
master thesis 2023
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van der Maarel, Merel (author)
The thesis consists of six chapters, including the introduction (Chapter 1), a literature study about the current state of e-health interventions in T2DM care (Chapter 2), the study design of the pilot study (Chapter 3) and the results of the pilot study about the educational care pathway (Chapters 4, 5 and 6). The pathway consists of three...
master thesis 2023
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Bolhuis, Luuk (author)
Neuromuscular blocking agents (NMBAs) are commonly employed in anesthesia to facilitate intubation and improve surgical working conditions. Understanding their pharmacokinetics (PK) and pharmacodynamics (PD) is crucial for optimizing their administration. PK describes drug absorption, distribution, metabolism, and elimination, while PD links...
master thesis 2023
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Josemans, Sabine (author)
Introduction<br/>In the Netherlands, approximately five thousand people are dependent on maintenance hemodialysis (HD) treatment. The one-year mortality of this patient population in 2021 was as high as 18%. A significant contributor to this high mortality and burden on HD patients is the high incidence of intradialytic hypotension (IDH), which...
master thesis 2023
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Zwinkels, Anouk (author)
<b>Introduction</b>: Deep brain stimulation (DBS) is an important therapeutic option for various neurological diseases. For certain indications the optimal target cannot be identified on structural magnetic resonance imaging (MRI), but can be visualized with tractography. A recent improvement for clinical practice is the probabilistic...
master thesis 2023
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Muller, Marjolein (author)
Introduction: Over the past two decades deep brain stimulation (DBS) has emerged as an important therapeutic option for Parkinson’s disease (PD). However, the current DBS programming method, monopolar review (MPR), is time-consuming, requires highly trained personnel and causes discomfort for patients. This study aimed to predict the optimal...
master thesis 2023
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van der Zwaard, Fenne (author)
Models for oxygen transport in preterm infants can aid the development and evaluation of automated oxygen controllers by providing insight into the FiO2-SpO2 response and enabling virtual trials. A computer simulation model of oxygen transport in preterm infants is developed and FiO2-SpO2 responses in preterm infants are investigated. The model...
master thesis 2023
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Hendriks, Manon (author)
Maasstad Hospital is a member of the Santeon hospital group. The ambition of Santeon is to improve healthcare for patients. The project in this internship also aims to improve patients’ health, specifically patients in the Intensive Care Unit (ICU).<br/>The treatment of respiratory insufficient patients in the ICU consists of High Flow Nasal...
master thesis 2023
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van Ravensberg, Annemiek (author)
Background: Solutions targeting early recognition of congestion in heart failure (HF) patients have the potential to prevent readmissions and can thus significantly reduce the burden on HF care. The gold standard measure of congestion is invasively measured pulmonary capillary wedge pressure (PCWP). However, the invasive nature and accessibility...
master thesis 2023
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Schouten, Janno (author)
Patients who are admitted to the Intensive Care Unit (ICU) are extremely ill and at high risk of organ failure and death. Being admitted to the ICU is known to cause long lasting physical, cognitive, and physiological symptoms, which is called Post-Intensive Care syndrome (PICS). To provide better management of PICS, early recognition and...
master thesis 2023
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Ihaddouchen, Imane (author)
Introduction: In intensive care units (ICU), the most significant life support technology for patients with acute respiratory failure is mechanical ventilation. A mismatch between ventilatory support and patient demand is referred to as patient-ventilator asynchrony (PVA), and it is associated with a series of adverse...
master thesis 2023
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Toet, Rowan (author)
Cardiothoracic surgery is a common treatment for cardiovascular diseases. Patients are admitted to the ICU after cardiothoracic surgery for continuous monitoring to prevent or treat postoperative complications as much and as soon as possible. One of these complications is the development of circulatory shock. It is likely caused by one or a...
master thesis 2023
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van der Graaf, Marijn (author)
Background and objectives: Mitochondria require oxygen to generate energy for essential cellular processes. An in-vivo non-invasive technique to monitor mitochondrial oxygen tension (mitoPO2) is the protoporphyrin IX-triplet state lifetime technique. Protoporphyrin IX (PpIX), one of the key components of heme, is naturally present in the...
master thesis 2022
Searched for: mods_note_programme_s%3A%22Technical%255C+Medicine%255C+%257C%255C+Sensing%255C+and%255C+Stimulation%22
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