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Jorda, J. (author), Cueto Rojas, H.F. (author), Carnicer, M. (author), Wahl, S.A. (author), Ferrer, P. (author), Albiol, J. (author)Pichia pastoris has been recognized as an effective host for recombinant protein production. In this work, we combine metabolomics and instationary 13C metabolic flux analysis (INST 13C-MFA) using GC-MS and LC-MS/MS to evaluate the potential impact of the production of a Rhizopus oryzae lipase (Rol) on P. pastoris central carbon metabolism....journal article 2014